Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

Αρχειοθήκη ιστολογίου

! # Ola via Alexandros G.Sfakianakis on Inoreader

Η λίστα ιστολογίων μου

Σάββατο 9 Ιουνίου 2018

Atypical Auditory Language Processing in Adolescents with Autism Spectrum Disorders

S13882457.gif

Publication date: Available online 8 June 2018
Source:Clinical Neurophysiology
Author(s): Junpei Tanigawa, Kuriko Kagitani-Shimono, Junko Matsuzaki, Rei Ogawa, Ryuzo Hanaie, Tomoka Yamamoto, Koji Tominaga, Shin Nabatame, Ikuko Mohri, Masako Taniike, Keiichi Ozono
ObjectiveIndividuals with autism spectrum disorder (ASD) often show characteristic differences in auditory processing. To clarify the mechanisms underlying communication impairment in ASD, we examined auditory language processing with both anatomical and functional methods.MethodsWe assessed the language abilities of adolescents with ASD and typically developing (TD) adolescents, and analyzed the surface-based morphometric structure between the groups using magnetic resonance imaging. Furthermore, we measured cortical responses to an auditory word comprehension task with magnetoencephalography and performed network-based statistics using the phase locking values.ResultsWe observed no structural differences between the groups. However, the volume of the left ventral central sulcus (vCS) showed a significant correlation with linguistic scores in ASD. Moreover, adolescents with ASD showed weaker cortical activation in the left vCS and superior temporal sulcus. Furthermore, these regions showed differential correlations with linguistic scores between the groups. Moreover, the ASD group had an atypical gamma band (25–40 Hz) network centered on the left vCS.ConclusionsAdolescents with ASD showed atypical responses on the auditory word comprehension task and functional brain differences.SignificanceOur results suggest that phonological processing and gamma band cortical activity play a critical role in auditory language processing-related pathophysiology in adolescents with ASD.



https://ift.tt/2kX7eWi

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αρχειοθήκη ιστολογίου