Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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! # Ola via Alexandros G.Sfakianakis on Inoreader

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Δευτέρα 13 Ιουλίου 2020


Quantum aspects of evolution: a contribution toward evolutionary explorations of genotype networks via quantum walks [NEW RESULTS]
Quantum biology seeks to explain biological phenomena via quantum mechanisms, such as enzyme reaction rates via tunneling and photosynthesis energy efficiency via coherent superposition of states. However, less effort has been devoted to study the role of quantum mechanisms in biological evolution. In this paper, we used transcription factor networks with two and four different phenotypes, and used classical random walks (CRW) and quantum walks (QW) to compare network search behavior and efficiency...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
Whole-Proteome Tree of Arthropods: An "alignment-free" phylogeny of proteome "books" [NEW RESULTS]
Background: An organism tree of a group of extant-organisms can be considered as a conceptual tree to capture a simplified narrative of the evolutionary course among the organisms. Due to the difficulties of whole-genome sequencing for many organisms, the most common approach has been to construct a gene tree by selecting a group of genes common among the organisms, align each gene family and estimate evolutionary distances. Despite broad acceptance of the gene trees as the surrogates for the organism...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
Genomic Evidences Support an Independent History of Grapevine Domestication in the Levant [NEW RESULTS]
The ancient grapevines of the Levant have inspired beliefs and rituals in human societies which are still practiced today in religious and traditional ceremonies around the world. Despite their importance, the original Levantine wine-grapes varieties were lost due to cultural turnovers commencing in the 7th century CE, which lead to the collapse of a flourishing winemaking industry in this region. Recently, a comprehensive survey of feral grapevines was conducted in Israel in an attempt to identify...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
A framework to quantify phenotypic and genotypic parallel evolution [NEW RESULTS]
The independent and repeated adaptation of populations to similar environments often results in the evolution of similar forms. This phenomenon creates a strong correlation between phenotype and environment and is referred to as parallel evolution. However, there is ongoing debate as to when we should call a system either phenotypically or genotypically 'parallel.' Here, we suggest a novel and simple framework to quantify parallel evolution at the genotypic and phenotypic levels. Our framework combines...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
Geography is more important than life history in the recent diversification of the tiger salamander complex [NEW RESULTS]
The North American tiger salamander species complex, including its flagship species the axolotl, has long been a source of biological fascination. The complex exhibits a wide range of variation in developmental life history strategies, including populations and individuals that undergo metamorphosis and those able to forego metamorphosis and retain a larval, aquatic lifestyle (i.e., paedomorphosis). Such disparate life history strategies are assumed to cause populations to become reproductively isolated,...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
Constrained non-coding sequence provides insights into regulatory elements and loss of gene expression in maize [NEW RESULTS]
DNA sequencing technology has advanced so quickly, identifying key functional regions using evolutionary approaches is required to understand how those genomes work. This research develops a sensitive sequence alignment approach to identify functional constrained non-coding sequences in the Andropogoneae tribe. The grass tribe Andropogoneae contains several crop species descended from a common ancestor ~18 million years ago. Despite broadly similar phenotypes, they have tremendous genomic diversity...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
TAXON INCOMPLETENESS AND DISCRETE TIME BINS AFFECT CHARACTER CHANGE RATES IN SIMULATED DATA [CONFIRMATORY RESULTS]
Estimating how fast or slow morphology evolves through time (phenotypic change rate; PR) has become common in macroevolutionary studies, and has been important for clarifying key evolutionary events. However, the inclusion of incompletely scored taxa (e.g., fossils) could affect PR estimates and potentially mask real PR patterns. This effect being also affected by the usage of arbitrary discrete time bins. Here, the impact of taxon incompleteness (unscored data) on PR estimates is assessed in simulated...
bioRxiv Subject Collection: Evolutionary Biology
Sun Jul 12, 2020 03:00
Communication Skills Training for Internal Medicine Residents Using a Brief Animated Video
Abstract Patient communication courses are time-intensive, making incorporation into residency curricula challenging. Using a short video could be an efficient means to teach residents communication skills. We created a 4-min animated video focused on the “ask more and summarize technique”. Residents rotating on the inpatient oncology and palliative care service received a video link with a survey (S1) on the tool and its projected utility. A second survey (S2) was sent upon rotation...
Journal of Cancer Education
Mon Jul 13, 2020 03:00
[ASAP] Catalyzed Kinetic Growth in Two-Dimensional MoS<sub>2</sub>
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05057
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Asymmetric Total Synthesis of Bufospirostenin A
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05479
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] An Expandable Hydrogen-Bonded Organic Framework Characterized by Three-Dimensional Electron Diffraction
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04885
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] A W/Cu Synthetic Model for the Mo/Cu Cofactor of Aerobic CODH Indicates That Biochemical CO Oxidation Requires a Frustrated Lewis Acid/Base Pair
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03343
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Metal-Free Direct Deoxygenative Borylation of Aldehydes and Ketones
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03813
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Unifying Mechanism for Thiol-Induced Photoswitching and Photostability of Cyanine Dyes
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03786
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Molecular Origin of the Odd–Even Effect of Macroscopic Properties of <italic toggle="yes">n</italic>-Alkanethiolate Self-Assembled Monolayers: Bulk or Interface?
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04288
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Nanoscale Metal–Organic Framework Co-delivers TLR-7 Agonists and Anti-CD47 Antibodies to Modulate Macrophages and Orchestrate Cancer Immunotherapy
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05039
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04722
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] ZnMe<sub>2</sub>-Mediated, Direct Alkylation of Electron-Deficient N-Heteroarenes with 1,1-Diborylalkanes: Scope and Mechanism
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06827
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Enhanced Stabilization and Easy Phase Transfer of CsPbBr<sub>3</sub> Perovskite Quantum Dots Promoted by High-Affinity Polyzwitterionic Ligands
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03682
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Redox Noninnocent Monoatomic Silicon(0) Complex (“Silylone”): Its One-Electron-Reduction Induces an Intramolecular One-Electron-Oxidation of Silicon(0) to Silicon(I)
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06238
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Mon Jul 13, 2020 07:00
[ASAP] Solvation Dynamics and the Nature of Reaction Barriers and Ion-Pair Intermediates in Carbocation Reactions
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06295
Journal of the American Chemical Society: Latest Articles (ACS Publications)
Sun Jul 12, 2020 07:00
Head errors of syntactic dependency increase neuromagnetic mismatch intensities
Abstract Mismatch-related brain activation in healthy individuals is an important area of neural investigation. Previously, we evaluated sentence-level syntactic dependencies, composed of a head and a dependent between two syntactically related words in head-initial English structures. We demonstrated that prominent mismatch effects were induced by within-category dependent errors when semantic interpretation was preserved. However, the following issues were not addressed: (1)...
Experimental Brain Research
Mon Jul 13, 2020 03:00
Special issue in honor of John C. Rothwell
Experimental Brain Research
Mon Jul 13, 2020 03:00
Dissecting two distinct interneuronal networks in M1 with transcranial magnetic stimulation
Abstract Interactions from both inhibitory and excitatory interneurons are necessary components of cortical processing that contribute to the vast amount of motor actions executed by humans daily. As transcranial magnetic stimulation (TMS) over primary motor cortex is capable of activating corticospinal neurons trans-synaptically, studies over the past 30 years have provided how subtle changes in stimulation parameters (i.e., current direction, pulse width, and paired-pulse) can...
Experimental Brain Research
Mon Jul 13, 2020 03:00
Body illusion and affordances: the influence of body representation on a walking imagery task in virtual reality
Abstract It is well known that our body works as a fundamental reference when we perform visuo-perceptual judgements in spatial surroundings, and that body illusions can modify our perception of size and distance of objects in space. To date, however, few studies have evaluated whether or not a body illusion could have a significant impact on the way individuals perceive to move within the environment. Here, we used a full-body illusion paradigm to verify the hypothesis that an...
Experimental Brain Research
Mon Jul 13, 2020 03:00
Effects of force level and task difficulty on force control performance in elderly people
Abstract As the proportion of people over 60 years of age rises continuously in westernized societies, it becomes increasingly important to better understand aging processes and how to maintain independence in old age. Fine motor tasks are essential in daily living and, therefore, necessary to maintain. This paper extends the existing literature on fine motor control by manipulating the difficulty of a force maintenance task to characterize performance optima for elderly. Thirty-seven...
Experimental Brain Research
Mon Jul 13, 2020 03:00
Effects of aging on rapid grip force responses during bimanual manipulation of an active object
Abstract Rapid grip force responses to unexpected pulling loads on the fingertips are deteriorated in older adults due to, in part, age-related declines in somatosensory function. Such reports are limited to one-hand conditions despite the higher frequency of using two hands together in daily living activities of older adults. Unexpected perturbations during bimanual movements elicit goal-oriented and cortically-meditated bilateral rapid motor responses. Since aging is associated...
Experimental Brain Research
Mon Jul 13, 2020 03:00
DGUOK-AS1 promotes the proliferation cervical cancer through regulating miR-653-5p/EMSY
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Cancer Biology & Therapy: Table of Contents: Taylor and Francis
Mon Jul 13, 2020 10:50
[ASAP] Fluorescent Probe for Simultaneous Discrimination of GSH, Cys, and SO<sub>2</sub> Derivatives
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02255
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Amplification and Preparation of Cellular O-Glycomes for Functional Glycomics
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00632
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] AFM-Based High-Throughput Nanomechanical Screening of Single Extracellular Vesicles
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05716
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Quantifying Interferent Effects on Molecularly Imprinted Polymer Sensors for Per- and Polyfluoroalkyl Substances (PFAS)
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01565
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] In-Depth Cannabis Multiclass Metabolite Profiling Using Sorptive Extraction and Multidimensional Gas Chromatography with Low- and High-Resolution Mass Spectrometry
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01301
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Absolute Cross Sections of Liquids from Broadband Stimulated Raman Scattering with Femtosecond and Picosecond Pulses
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01785
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Recessed Ag/AgCl Microelectrode-Supported Lipid Bilayer for Nanopore Sensing
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02720
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] The Next Generation of IR Spectroscopy: EC-QCL-Based Mid-IR Transmission Spectroscopy of Proteins with Balanced Detection
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01406
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Evaluation of the Deterioration State of Archaeological Wooden Artifacts: A Nondestructive Protocol based on Direct Analysis in Real Time – Mass Spectrometry (DART-MS) Coupled to Chemometrics
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01429
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Single-Cell Mass Spectrometry Analysis of Metabolites Facilitated by Cell Electro-Migration and Electroporation
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02147
Analytical Chemistry
Mon Jul 13, 2020 07:00
[ASAP] Conformational Conversion Enhances Cellular Uptake of F Base Double-Strand-Conjugated Oligonucleotides
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00614
Analytical Chemistry
Mon Jul 13, 2020 07:00

[ASAP] Sequencing a Bispecific Antibody by Controlling Chain Concentration Effects When Using an Immobilized Nonspecific Protease
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01126
Analytical Chemistry
Mon Jul 13, 2020 07:00

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