Proliferative verrucous leukoplakia: diagnosis, management and current advances.

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Proliferative verrucous leukoplakia: diagnosis, management and current advances.

Braz J Otorhinolaryngol. 2017 Jan 24;:

Authors: Capella DL, Gonçalves JM, Abrantes AA, Grando LJ, Daniel FI

Abstract
INTRODUCTION: Proliferative verrucous leukoplakia is a multifocal and progressive lesion of the oral mucosa, with unknown etiology, and commonly resistant to all therapy attempts with frequent recurrences. It is characterized by a high rate of oral squamous cell carcinoma and verrucou carcinoma transformations.
OBJECTIVE: To analyze the studies about Proliferative verrucous leukoplakia and develop a concise update.
METHODS: A Pubmed search identifying studies (laboratory research, case series and reviews of literature) that examined patients with Proliferative verrucous leukoplakia was realized.
RESULTS: There are not enough studies about Proliferative verrucous leukoplakia in the literature. The few found studies not present a consensus about its etiology and diagnosis criteria. Although several treatment strategies have been proposed, most of them still show a high recurrence rate.
CONCLUSION: More research about Proliferative verrucous leukoplakia is necessary to understand and treat this disease.

PMID: 28209441 [PubMed - as supplied by publisher]

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