Publication date: Available online 1 July 2017
Source:Seminars in Cancer Biology
Author(s): Cornelia Braicu, Nikolay Mehterov, Boyan Vladimirov, Victoria Sarafian, Seyed Nabavi, Atanas G. Atanasov, Ioana Berindan-Neagoe
Nutrigenomics effects have an important role in the manipulation of dietary components for human benefit, particularly in cancer prevention or treatment. The impact of dietary components, including phytochemicals, is largely studied by nutrigenomics, looking at the gene expression and molecular mechanisms interacting with bioactive compounds and nutrients, based on new 'omics' technologies. The high number of preclinical studies proves the relevant role of nutrigenomics in cancer management. By deciphering the network of nutrient-gene connections associated with cancer, relevant data will be transposed as therapeutic interventions for this devastating pathology and for fulfilling the concept of personalized nutrition. All these are presented under the nutrigenomics canopy for a better comprehension of the relation between ingested phytochemicals and chemoprevention or chemotherapy. The profits from the nutrigenomics progress, with a particular focus on the coding and noncoding genes related to the exposure of natural compounds need to be validated. A precise attention receives the evaluation of the role of natural compounds in tandem with conventional therapy using genomic approaches, with emphasis on the capacity to inhibit drug resistance mechanisms. All these relevant nutrigenomics aspects are summarized in the present review paper. It is concluded that further nutrigenomics studies are required to improve our understanding related to the complex mechanisms of action of the natural compounds and for their appropriate application as gears in cancer therapy.
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- Consecutive occurrence of isotopic and isomorphic ...
- Superficial plantar angiomyxoma in a young man
- Consecutive occurrence of isotopic and isomorphic ...
- Superficial plantar angiomyxoma in a young man
- The dog days or dog days of summer are the hot, su...
- Brassica rapa hairy root extracts promote skin dep...
- Brassica rapa hairy root extracts promote skin dep...
- Measurement of Pharyngo-laryngeal Volume During Sw...
- Subcutaneous mycoses in Peru: a systematic review ...
- Burden and health-related quality of life of eatin...
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- CIK as therapeutic agents against tumors
- A Case of Atopic Myelitis with Cervical Cavernous ...
- A call to arms of specialty societies to review th...
- The atopic disorders and atopy … “strange diseases...
- Atopic dermatitis treatment: Current state of the ...
- Efficacy and safety of omalizumab in children and ...
- A 6-month safety and efficacy study of fluticasone...
- Asthma in older people hospitalized with influenza...
- Prevalence and triggers of anaphylactic events in ...
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- Prevalence and triggers of anaphylactic events in ...
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- A 10-year experience of a novel and safe modified ...
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- For the Patient: Prevalence and triggers of anaphy...
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- Can Residents Be Trained and Safety Maintained?
- Multiple Non-Syndromic Bilaterally Erupted Para Pr...
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- Eltrombopag for People With Fanconi Anemia
- NCI UNC Project ESCC
- Eltrombopag for People With Fanconi Anemia
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- Facial Reconstruction Post-Mohs Surgery
- Reconstruction of Mohs Defects of the Lips and Chin
- Reconstruction of Cheek Defects Secondary to Mohs ...
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- Contents
- Skin and Composite Grafting Techniques in Facial R...
- Defect of the Eyelids
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- Repair of Auricular Defects
- Facial Reconstruction Post-Mohs Surgery
- Reconstruction of Mohs Defects of the Lips and Chin
- Reconstruction of Cheek Defects Secondary to Mohs ...
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- In Pursuit of Perfection: The Art of Facial Restor...
- Personality predicts the vibrancy of colour imager...
- Emergency Department Flow Measures for Adult and P...
- Autophagy inhibition enabled efficient phototherma...
- Editorial board
- Macrophages with cellular backpacks for targeted d...
- Effects of allergen sensitization on response to t...
- Epinephrine use for anaphylaxis: Too seldom, too late
- Corrigendum to “Management Challenges in a Child w...
- Efficacy of oral immunotherapy with a rice-based e...
- Prodrugs in medicinal chemistry and enzyme prodrug...
- Serum Wisteria floribunda agglutinin-positive Mac-...
- Acceleration of skin wound healing by low-dose ind...
- High frequencies of a favorable IL-28B rs8099917 p...
- Evaluation of Sedation-Related Medication Errors i...
- Synthesis and biological evaluation of novel stero...
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