Publication date: Available online 27 June 2017
Source:Trends in Immunology
Author(s): Adriana Forero, Lomon So, Ram Savan
miRNAs play an important role in fine-tuning host immune homeostasis and responses through the regulation of mRNA stability and translation. Studies have demonstrated that miRNA-mediated regulation of gene expression has a profound impact on immune cell development, function, and response to invading pathogens. As we continue to examine the mechanisms by which miRNAs maintain the balance between robust protective host immune responses and dysregulated responses that promote immune pathology, careful consideration of the complexity of post-transcriptional immune regulation is needed. Distinct tissue- and stimulus-specific RNA–RNA and RNA–protein interactions can modulate the functions of a given miRNA. Thus, new challenges emerge in the identification of post-transcriptional coregulatory modules and the genetic factors that impact miRNA function.
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ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
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00302841026182
00306932607174
alsfakia@gmail.com
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Re-evaluating Strategies to Define the Immunoregulatory Roles of miRNAs
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- Head and Neck Diseases
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- Host Genetics and Gut Microbiome: Challenges and P...
- Re-evaluating Strategies to Define the Immunoregul...
- Molecular Dissection of CD8+ T-Cell Dysfunction
- Consecutive occurrence of isotopic and isomorphic ...
- Superficial plantar angiomyxoma in a young man
- Consecutive occurrence of isotopic and isomorphic ...
- Superficial plantar angiomyxoma in a young man
- The dog days or dog days of summer are the hot, su...
- Brassica rapa hairy root extracts promote skin dep...
- Brassica rapa hairy root extracts promote skin dep...
- Measurement of Pharyngo-laryngeal Volume During Sw...
- Subcutaneous mycoses in Peru: a systematic review ...
- Burden and health-related quality of life of eatin...
- Issue Information
- CIK as therapeutic agents against tumors
- A Case of Atopic Myelitis with Cervical Cavernous ...
- A call to arms of specialty societies to review th...
- The atopic disorders and atopy … “strange diseases...
- Atopic dermatitis treatment: Current state of the ...
- Efficacy and safety of omalizumab in children and ...
- A 6-month safety and efficacy study of fluticasone...
- Asthma in older people hospitalized with influenza...
- Prevalence and triggers of anaphylactic events in ...
- Seasonal variation and monthly patterns of skin sy...
- Association of maternal depression and allergic di...
- A 10-year experience of a novel and safe modified ...
- Pearls and pitfalls: Autoimmune lymphoproliferativ...
- A 28-year-old woman with fever, rash, and pancytop...
- For the Patient: Prevalence and triggers of anaphy...
- Abstracts from the New England Society of Allergy ...
- A call to arms of specialty societies to review th...
- The atopic disorders and atopy … “strange diseases...
- Atopic dermatitis treatment: Current state of the ...
- Efficacy and safety of omalizumab in children and ...
- A 6-month safety and efficacy study of fluticasone...
- Asthma in older people hospitalized with influenza...
- Prevalence and triggers of anaphylactic events in ...
- Seasonal variation and monthly patterns of skin sy...
- Association of maternal depression and allergic di...
- A 10-year experience of a novel and safe modified ...
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- A 28-year-old woman with fever, rash, and pancytop...
- For the Patient: Prevalence and triggers of anaphy...
- Abstracts from the New England Society of Allergy ...
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- Defect of the Eyelids
- Flap Basics III
- Forthcoming Issues
- Flap Basics II
- Index
- Repair of Auricular Defects
- Facial Reconstruction Post-Mohs Surgery
- Reconstruction of Mohs Defects of the Lips and Chin
- Reconstruction of Cheek Defects Secondary to Mohs ...
- Copyright
- In Pursuit of Perfection: The Art of Facial Restor...
- Contributors
- Contents
- Skin and Composite Grafting Techniques in Facial R...
- Defect of the Eyelids
- Flap Basics III
- Forthcoming Issues
- Flap Basics II
- Index
- Repair of Auricular Defects
- Facial Reconstruction Post-Mohs Surgery
- Reconstruction of Mohs Defects of the Lips and Chin
- Reconstruction of Cheek Defects Secondary to Mohs ...
- Copyright
- In Pursuit of Perfection: The Art of Facial Restor...
- Personality predicts the vibrancy of colour imager...
- Emergency Department Flow Measures for Adult and P...
- Autophagy inhibition enabled efficient phototherma...
- Editorial board
- Macrophages with cellular backpacks for targeted d...
- Effects of allergen sensitization on response to t...
- Epinephrine use for anaphylaxis: Too seldom, too late
- Corrigendum to “Management Challenges in a Child w...
- Efficacy of oral immunotherapy with a rice-based e...
- Prodrugs in medicinal chemistry and enzyme prodrug...
- Serum Wisteria floribunda agglutinin-positive Mac-...
- Acceleration of skin wound healing by low-dose ind...
- High frequencies of a favorable IL-28B rs8099917 p...
- Evaluation of Sedation-Related Medication Errors i...
- Synthesis and biological evaluation of novel stero...
- Staged definitive repair after carotid blowout: a ...
- Joint Attention and Oromotor Abilities in Young Ch...
- Geospatial analysis of dissolved nutrients dataset...
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