Ultrasensitive detection of ochratoxin A using aptasensors

Publication date: 15 December 2017
Source:Biosensors and Bioelectronics, Volume 98
Author(s): Hasan Badie Bostan, Noor Mohammad Danesh, Gholamreza Karimi, Mohammad Ramezani, Seyed Ali Mousavi Shaegh, Kazem Youssefi, Fahimeh Charbgoo, Khalil Abnous, Seyed Mohammad Taghdisi
Regarding teratogenic, carcinogenic, and immunotoxic nature of ochratoxin A (OTA), selective and sensitive monitoring of this molecule in food samples is of great importance. In recent years, various methods have been introduced for detection of OTA. However, they are usually time-consuming, labor-intensive and expensive. Therefore, these parameters limited their usage. The emerging method of detection, aptasensor, has attracted more attention for OTA detection, due to distinctive advantages including high sensitivity, selectivity and simplicity. In this review, the new developed aptasensors for detection of OTA have been investigated. We also highlighted advantages and disadvantages of different types of OTA aptasensors. This review also takes into consideration the goal to find out which designs are the most rational ones for highly sensitive detection of OTA.



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