Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Δευτέρα 3 Αυγούστου 2020


Efficacy of toluidine blue in the diagnosis and screening of oral cancer and precancer: A systematic review and meta-analysis.
Efficacy of toluidine blue in the diagnosis and screening of oral cancer and precancer: A systematic review and meta-analysis. Clin Otolaryngol. 2020 Aug 01;: Authors: Kim DH, Song EA, Kim SW, Hwang SH Abstract AIMS: The accuracy of toluidine blue (TB) and chemiluminescence for diagnosing oral cancer and precancer was evaluated. METHODS: Two authors (working independently) comprehensively reviewed six databases (PubMed, Cochrane...
Head and Neck
Mon Aug 03, 2020 13:22
Concurrent chemoradiotherapy with low-dose weekly platinum agent for head and neck carcinoma.
Concurrent chemoradiotherapy with low-dose weekly platinum agent for head and neck carcinoma. Clin Otolaryngol. 2020 Aug 01;: Authors: Kitano M, Kojima T, Okanoue Y, Fujimura S, Oyagi S, Shoji K, Hori R Abstract 1. Combined radiation therapy and every-3-weeks high-dose cisplatin has been often reported for head and neck cancer. However, this regimen can cause both severe acute complications and late complications. 2. The objective of this...
Head and Neck
Mon Aug 03, 2020 13:22
Altered expression of CCN1 in oral lichen planus associated with keratinocyte activation and IL-1β, ICAM1 and CCL5 up-regulation.
Altered expression of CCN1 in oral lichen planus associated with keratinocyte activation and IL-1β, ICAM1 and CCL5 up-regulation. J Oral Pathol Med. 2020 Aug 02;: Authors: Wang Y, Du G, Shi L, Shen X, Shen Z, Liu W Abstract BACKGROUND: Emerging evidence indicates that CCN1 is a novel inflammation-regulated mediator involved in the pathogenesis of some immune-mediated inflammatory diseases. The objective of this study was to investigate...
Head and Neck
Mon Aug 03, 2020 13:22
Artemisia annua- sublingual immunotherapy: first step to cross the chasm.
Artemisia annua- sublingual immunotherapy: first step to cross the chasm. Allergy. 2020 Aug 02;: Authors: Xian M, Zhang L Abstract The prevalence of allergic rhinitis (AR) has witnessed a progressive increase in China. A survey of self-reported AR using validated questionnaire-based telephone interviews in adult subjects conducted between 2004 and 2005 demonstrated that the prevalence of AR in 11 major cities across China was 11.1%1 ....
Head and Neck
Mon Aug 03, 2020 13:22
Telemedicine in Otolaryngology in the COVID-19 Era: Initial Lessons Learned.
Telemedicine in Otolaryngology in the COVID-19 Era: Initial Lessons Learned. Laryngoscope. 2020 Aug 02;: Authors: Ohlstein JF, Garner J, Takashima M Abstract OBJECTIVES: The COVID-19 pandemic has led to unprecedented global changes in the delivery of healthcare over a short period of time. With the implementation of "shelter in place" orders, otolaryngology clinic visits at our institution were transitioned to Telemedicine. This change...
Head and Neck
Mon Aug 03, 2020 13:22
The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy.
The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy. Support Care Cancer. 2020 Aug 01;: Authors: Jovanovic N, Dreyer C, Hawkins S, Thouless K, Palma D, Doyle PC, Theurer JA Abstract PURPOSE: Patients treated for oropharyngeal cancer (OPC) are at increased risk for functional decline due to cancer-related impairments and treatment toxicities, often...
Head and Neck
Mon Aug 03, 2020 13:22
Correction to: Two different therapies for the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis.
Correction to: Two different therapies for the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis. Eur Arch Otorhinolaryngol. 2020 Aug 01;: Authors: Zhu M, Yan Y, Gong H, Wu Y, Tan G Abstract In the original publication of the article, Fig. 1a was missing and caption of Fig. 1a was published as caption of Fig. 1b. The correct Fig. 1 and captions are provided below. PMID: 32740719 [PubMed - as supplied...
Head and Neck
Mon Aug 03, 2020 13:22
Granular cell tumors of the sellar region: what should be done after subtotal resection? A systematic review.
Granular cell tumors of the sellar region: what should be done after subtotal resection? A systematic review. Pituitary. 2020 Aug 01;: Authors: Rubino F, Martinez-Perez R, Vieira S, Voscoboinik DS, Mural M, Orr AJ, Hardesty DA, Carrau RL, Prevedello DM Abstract PURPOSE: Granular cell tumors (GCT) are highly vascularized and adherent to adjacent structures, and so, complete resection represents a challenge. Adjuvant therapy decisions for...
Head and Neck
Mon Aug 03, 2020 13:22
Failure of Free Flaps in Head and Neck Oncology Surgery in COVID-19 Patients.
Failure of Free Flaps in Head and Neck Oncology Surgery in COVID-19 Patients. Plast Reconstr Surg. 2020 Aug;146(2):251e-252e Authors: Benmoussa N, de Kerangal Q, Leymarie N, Breuskin I, Rigal T, Alkhashnam H, Tendron A PMID: 32740633 [PubMed - as supplied by publisher]
Head and Neck
Mon Aug 03, 2020 13:22
The Clinical Spectrum of Dizziness in Sleep Apnea.
The Clinical Spectrum of Dizziness in Sleep Apnea. Otol Neurotol. 2020 Jul 27;: Authors: Foster CA, Machala M Abstract OBJECTIVE: Sleep apnea has been associated with dizziness, but the clinical characteristics of this dizziness have not been fully described. This study evaluated clinical descriptions of dizziness, vestibular diagnoses, and the response to treatment of dizzy patients with sleep apnea. PATIENTS: All subjects had...
Head and Neck
Mon Aug 03, 2020 13:22
MITF Is Mutated in Type 1 Waardenburg Syndrome With Unusual Phenotype.
MITF Is Mutated in Type 1 Waardenburg Syndrome With Unusual Phenotype. Otol Neurotol. 2020 Jul 27;: Authors: Li W, Feng Y, Chen H, He C, Mei L, Liu XZ, Men M Abstract BACKGROUND: Waardenburg syndrome (WS) is a rare disorder characterized by varying combinations of sensorineural hearing loss and abnormal pigmentation of the hair and skin. WS is classified into four subtypes (WS1-WS4) based on additional symptoms. Dystopia canthorum is a...
Head and Neck
Mon Aug 03, 2020 13:22
Changes in Bone Conduction Implant Geometry Improve the Bone Fit in Mastoids of Children and Young Adults.
Changes in Bone Conduction Implant Geometry Improve the Bone Fit in Mastoids of Children and Young Adults. Otol Neurotol. 2020 Jul 27;: Authors: Wenzel C, Schilde S, Plontke SK, Rahne T Abstract OBJECTIVES: In 2012 the first active bone conduction implant was introduced, but did not fit into the mastoids of some adults and many children. Thus, a geometry change of the transducer was proposed (BCI 602). In this study, we aimed to determine...
Head and Neck
Mon Aug 03, 2020 13:22
Pentoxifylline and Tocopherol in the Management of Temporal Bone Osteoradionecrosis: A Case Series.
Pentoxifylline and Tocopherol in the Management of Temporal Bone Osteoradionecrosis: A Case Series. Otol Neurotol. 2020 Jul 27;: Authors: Lovin BD, Choi JS, Lindquist NR, Phan J, Gidley PW, Nader ME Abstract OBJECTIVE: Temporal bone osteoradionecrosis (TBORN) is a rare, chronic complication of head and neck radiation. Initial treatment consists of conservative management, with surgical resection of necrotic bone indicated for cases of...
Head and Neck
Mon Aug 03, 2020 13:22
When Opposites Attract: Pediatric Cochlear Implantation in the Setting of Cerebrospinal Fluid Shunts.
When Opposites Attract: Pediatric Cochlear Implantation in the Setting of Cerebrospinal Fluid Shunts. Otol Neurotol. 2020 Jul 27;: Authors: Selleck AM, Park LR, Brown KD Abstract OBJECTIVE: The Food and Drug Administration (FDA) has recently raised concern regarding the safety of cochlear implantation in the setting of programmable cerebrospinal fluid shunts. The purpose of this study was to evaluate the outcomes and complications of cochlear...
Head and Neck
Mon Aug 03, 2020 13:22
Comparing Cochlear Duct Lengths Between CT and MR Images Using an Otological Surgical Planning Software.
Comparing Cochlear Duct Lengths Between CT and MR Images Using an Otological Surgical Planning Software. Otol Neurotol. 2020 Jul 27;: Authors: George-Jones NA, Tolisano AM, Kutz JW, Isaacson B, Hunter JB Abstract OBJECTIVE: We sought to examine the intra- and interobserver variability in measuring the cochlear duct length (CDL) from magnetic resonance imaging (MRI) images versus computed tomography (CT) images using an otological surgical...
Head and Neck
Mon Aug 03, 2020 13:22
Congenital Hearing Loss Is Associated With a High Incidence of Central Nervous System Abnormalities.
Congenital Hearing Loss Is Associated With a High Incidence of Central Nervous System Abnormalities. Otol Neurotol. 2020 Jul 27;: Authors: Sayyid ZN, Boldt B, Mokhtari TE, Schoppy K, Yeom KW, Cheng AG Abstract OBJECTIVE(S): To assess the incidence of central nervous system abnormalities in pediatric subjects with sensorineural hearing loss (SNHL). METHODS: One hundred forty-three pediatric subjects evaluated for SNHL at a single...
Head and Neck
Mon Aug 03, 2020 13:22
Are There Real-world Benefits to Bimodal Listening?
Are There Real-world Benefits to Bimodal Listening? Otol Neurotol. 2020 Jul 27;: Authors: Nyirjesy S, Rodman C, Tamati TN, Moberly AC Abstract OBJECTIVE: To assess the benefits of bimodal listening (i.e., addition of contralateral hearing aid) for cochlear implant (CI) users on real-world tasks involving high-talker variability speech materials, environmental sounds, and self-reported quality of life (quality of hearing) in listeners'...
Head and Neck
Mon Aug 03, 2020 13:22
Hearing Outcomes of Treatment for Acute Noise-Induced Hearing Loss: A Systematic Review and Meta-Analysis.
Hearing Outcomes of Treatment for Acute Noise-Induced Hearing Loss: A Systematic Review and Meta-Analysis. Otol Neurotol. 2020 Jul 27;: Authors: Koochakzadeh S, Gupta A, Nguyen SA, McRackan TR, Kil J, Bhenswala PN, Lambert PR Abstract OBJECTIVE: To determine the efficacy of various treatment modalities used for acute noise-induced hearing loss (aNIHL) from acute acoustic trauma (AAT) via a systematic review and meta-analysis. ...
Head and Neck
Mon Aug 03, 2020 13:22
Endoscopic Stapedectomy: Collective Experience From a Large Australian Center.
Endoscopic Stapedectomy: Collective Experience From a Large Australian Center. Otol Neurotol. 2020 Jul 27;: Authors: Vaughan C, Fox R, Jufas N, Kong JHK, Patel NP, Saxby AJ Abstract INTRODUCTION: Endoscopic stapes surgery is a technically demanding procedure that is increasing in popularity. Surgical outcomes and complication rates have been demonstrated to be comparable to traditional microscopic techniques. The surgical outcomes for...
Head and Neck
Mon Aug 03, 2020 13:22
Clinical and Economic Impact of The Global Smile Foundation Surgical Program.
Clinical and Economic Impact of The Global Smile Foundation Surgical Program. J Craniofac Surg. 2020 Jul 27;: Authors: Kantar RS, Chahine EM, Ghotmi LH, McAleer CM, Mera DF, Annan B, Haddad AG, Johnson AB, Hamdan US PMID: 32740315 [PubMed - as supplied by publisher]
Head and Neck
Mon Aug 03, 2020 13:22
Loss to Follow-Up After Newborn Hearing Screening: Analysis of Risk Factors at a Massachusetts Urban Safety-Net Hospital.
Loss to Follow-Up After Newborn Hearing Screening: Analysis of Risk Factors at a Massachusetts Urban Safety-Net Hospital. Ear Hear. 2020 Jul 23;: Authors: Razak A, Fard D, Hubbell R, Cohen M, Hartman-Joshi K, Levi JR Abstract OBJECTIVES: This study examines the unique factors that influence loss to follow-up after newborn hearing screening for patients at a Massachusetts urban safety-net hospital. We seek to characterize our patient population,...
Head and Neck
Mon Aug 03, 2020 13:22
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection.
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection. EBioMedicine. 2020 Jul 30;58:102905 Authors: Klinakis A, Rampias T Abstract BACKGROUND: Head and neck squamous cell carcinoma is a heterogeneous disease with respect to the anatomic site of the primary tumor. On the other hand, it is highly recurrent, and once metastatic, it is associated with poor prognosis. TP53 is the most commonly mutated...
Head and Neck
Mon Aug 03, 2020 13:22
Optimum surgical margins in squamous cell carcinoma of the oral tongue: Is the current definition adequate?
Optimum surgical margins in squamous cell carcinoma of the oral tongue: Is the current definition adequate? Oral Oncol. 2020 Jul 30;111:104938 Authors: Singh A, Mishra A, Singhvi H, Sharin F, Bal M, Laskar SG, Prabhash K, Chaturvedi P Abstract OBJECTIVES: To evaluate the impact of progressively increasing margin distances on locoregional recurrence-free survival (LFRS) and determine an optimum margin distance for tongue cancers. ...
Head and Neck
Mon Aug 03, 2020 13:22
Assessment of PIV performance in validating CFD models from nasal cavity CBCT scans.
Assessment of PIV performance in validating CFD models from nasal cavity CBCT scans. Respir Physiol Neurobiol. 2020 Jul 30;:103508 Authors: Ormiskangas J, Olli V, Kivekäs I, Dean M, Poe D, Järnstedt J, Lekkala J, Harju T, Saarenrinne P, Rautiainen M Abstract OBJECTIVE: The aim of our study was to investigate how well Particle Image Velocimetry (PIV) measurements could serve Computational Fluid Dynamics (CFD) model validation for nasal...
Head and Neck
Mon Aug 03, 2020 13:22
The diagnostic performance of ultrasound-guided core biopsy in the diagnosis of head and neck lymphoma: results in 226 patients.
The diagnostic performance of ultrasound-guided core biopsy in the diagnosis of head and neck lymphoma: results in 226 patients. Int J Oral Maxillofac Surg. 2020 Jul 29;: Authors: Cuenca-Jimenez T, Chia Z, Desai A, Moody A, Ramesar K, Grace R, Howlett DC Abstract Many clinical guidelines for investigating lymphomas advise that surgical excision biopsy (SEB) should be performed for a confident diagnosis. It is increasingly recognized in...
Head and Neck
Mon Aug 03, 2020 13:22
Transcervical dissection of metastatic suprahyoid retropharyngeal lymph nodes from papillary thyroid carcinoma through three anatomical barriers.
Transcervical dissection of metastatic suprahyoid retropharyngeal lymph nodes from papillary thyroid carcinoma through three anatomical barriers. Int J Oral Maxillofac Surg. 2020 Jul 29;: Authors: Chen S, Yang H, Su X, Yang A, Liu W Abstract Papillary thyroid carcinoma (PTC) rarely metastasizes to the suprahyoid retropharyngeal lymph nodes (SRPLNs). Studies on SRPLN metastasis from PTC and a description of the dissection of the SRPLNs...
Head and Neck
Mon Aug 03, 2020 13:22
Comparison of contrast-enhanced ultrasound and contrast-enhanced computed tomography for the diagnosis of cervical lymph node metastasis in squamous cell carcinoma of the oral cavity.
Comparison of contrast-enhanced ultrasound and contrast-enhanced computed tomography for the diagnosis of cervical lymph node metastasis in squamous cell carcinoma of the oral cavity. Int J Oral Maxillofac Surg. 2020 Jul 29;: Authors: Ding Z, Deng C, Wang Z, Liu L, Ma X, Huang J, Wang X, Xuan M, Xie H Abstract Early detection of cervical lymph node metastasis (CLNM) from squamous cell carcinoma (SCC) of the oral cavity remains challenging....
Head and Neck
Mon Aug 03, 2020 13:22
Non-recovery animal model of severe facial paralysis induced by freezing the facial canal.
Non-recovery animal model of severe facial paralysis induced by freezing the facial canal. Auris Nasus Larynx. 2020 Jul 29;: Authors: Joko T, Yamada H, Kimura T, Teraoka M, Hato N Abstract OBJECTIVE: Some cases of peripheral facial paralysis are resistant to treatment, thus, a non-recovery model of facial paralysis is needed to develop new treatment strategies for this condition. The purpose of the current study was to develop an animal...
Head and Neck
Mon Aug 03, 2020 13:22
Diving-related otological injuries: Initial assessment and management.
Diving-related otological injuries: Initial assessment and management. Aust J Gen Pract. 2020 08;49(8):500-504 Authors: Nofz L, Porrett J, Yii N, De Alwis N Abstract BACKGROUND: Scuba diving-related otological injuries comprise the majority of diving-related incidents that present to general practitioners (GPs). Correct diagnosis and management are key to prevent permanent hearing loss and vertigo. OBJECTIVE: The aim of this...
Head and Neck
Mon Aug 03, 2020 13:22
To Study the Role of Absolute Lymphocyte Count and RDW in COVID 19 Patients and their Association with Appearance of Symptoms and Severity.
To Study the Role of Absolute Lymphocyte Count and RDW in COVID 19 Patients and their Association with Appearance of Symptoms and Severity. J Assoc Physicians India. 2020 Aug;68(8):39-42 Authors: Sharma D, Dayama A, Banerjee S, Bhandhari S, Chatterjee A, Chatterjee D Abstract Objective: The present study was undertaken to evaluate prognostic relevance of select circulating immune mechanistic biomarkers in COVID-19 positive patients for...
Head and Neck
Mon Aug 03, 2020 13:22

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