Publication date: Available online 2 August 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Renato Luiz Maia Nogueira, Rafael Lima Verde Osterne, Renata de Matos Brito Lima Verde, Nayana Oliveira Azevedo, Renata Cordeiro Teixeira, Roberta Barroso Cavalcante
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We have read with interest various recent papers published on working from home and how productive one can try to be or how to preserve health.1 2 Although we very much appreciate how the healthcare service has embraced innovation to continue to deliver patient care throughout a pandemic, we wish to highlight some of the challenges faced by many working from home.As the COVID-19 pandemic took hold, we acquired laptops with access to laboratory results, electronic patient notes, radiology and various...
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Publication date: Available online 2 August 2020Source: Pathology - Research and PracticeAuthor(s): Raima A. Memon, Carlos N Prieto Granada, Shi Wei
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By Nala RogersResearchers have long debated why so many people lose their hearing as they age. Some have argued that the problem lies mainly with the stria vascularis, a sort of battery in the inner ear that powers the transformation of sound energy into nerve impulses. But a new study places the blame largely with hair cells -- the same sensory organs that are damaged by loud noises.Most details of the inner ear are impossible to examine while people are alive. To really see what’s going on, researchers...
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Publication date: Available online 2 August 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Jean Sénémaud, Raphael Coscas, Jean-Marc Alsac, Yves Castier, Quentin Pellenc, Jean-Baptiste Michel
Mon Aug 03, 2020 18:33
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Publication date: Available online 2 August 2020Source: TalantaAuthor(s): Dapeng Sun, Yi Wu, Shwu-Jen Chang, Ching-Jung Chen, Jen-Tsai Liu
Publication date: Available online 2 August 2020Source: TalantaAuthor(s): Elham Sadat Hosseini, Kourosh Tabar Heydar
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Publication date: Available online 2 August 2020Source: Clinical ImagingAuthor(s): Mayur Virarkar, Mohammed Saleh, Nisha Subhashchandra Ramani, Ajaykumar C. Morani, Priya Bhosale
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Publication date: September 2020Source: Journal of Human Evolution, Volume 146Author(s): W. Andrew Barr, Maryse Biernat
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The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy. Support Care Cancer. 2020 Aug 01;: Authors: Jovanovic N, Dreyer C, Hawkins S, Thouless K, Palma D, Doyle PC, Theurer JA Abstract PURPOSE: Patients treated for oropharyngeal cancer (OPC) are at increased risk for functional decline due to cancer-related impairments and treatment toxicities, often leading...
Psychometrics of the Functional Oral Intake Scale for Children with Dysphagia. J Pediatr Gastroenterol Nutr. 2020 Jul 28;: Authors: Yi YG, Shin HI Abstract OBJECTIVES: The functional oral intake scale (FOIS), developed for adults based on the categories of consumable food, has been adapted for infants. A FOIS for children is necessary, since oral motor development continues after one year of age. This study proposed a FOIS for children and...
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Here is a case of 35 year Indian origin male with backache with MRI revealed marrow edema in the sacral vertebral bodies along with presacral abscess noted on sagittal fat suppressed images. Interestingly before the MRI Xray didnot show much changes. In patients with osteomyelitis, MRI will pick up the changes earlier than plain xray.MRI SHOWING SARCAL EDEMA & PRESACRAL ABSCESS XRAY LS SPINE LATERAL VIEW Famous Radiology Blog http://www.sumerdoc.blogspot.com...
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Publication date: Available online 2 August 2020Source: Gene Expression PatternsAuthor(s): Jennifer L. Giffin, Tamara A. Franz-Odendaal
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Publication date: Available online 2 August 2020Source: Behavioural Brain ResearchAuthor(s): Jeffrey S. Darling, Daniel W. Bayless, Lauren R. Dartez, Joshua J. Taylor, Arjun Mehrotra, William L. Smith, Jill M. Daniel
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Body Dysmorphic Disorder (BDD) is a psychiatric disorder with delusions about defects in appearance for which patients seek various treatments. Patients with BDD often seek cosmetic procedures, and orthodontic...
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OBJECTIVE: Autism Spectrum Disorder is a complex brain disorder and has multiple causes that occur in diverse combinations. There is a need to classify children with ASD at a very young age so that they can access evidence-based intervention that can significantly improve their outcomes. CASE REPORT: In this report we present a case of autism, which underwent intrathecal autologous bone marrow mononuclear cells transplantation along with neurorehabilitation. The primary goal of the treatment is...
OBJECTIVE: Intensive care unit-acquired weakness (ICUAW) is common, and so far, there is no digital technology with a standard procedure to estimate the muscle strength of these patients. Quadriceps maximal isometric voluntary contraction (QMVC) is a precise and reliable procedure to detect quadriceps muscle strength. Therefore, this research aimed to explore whether QMVC measurements can be used in critically ill patients at the bedside as a potential diagnostic method. PATIENTS AND METHODS: Tailor-made...
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Publication date: Available online 2 August 2020Source: Clinical TherapeuticsAuthor(s): Sherin M. Pathickal, Tae Eun Park, Roopali Sharma
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OBJECTIVE: Determination of lipoprotein size and subclasses distribution can provide more significant information on cardiovascular disease risk than measurement of traditional lipid parameters alone. Accordingly, we aimed to examine their potential relationship with the novel biomarker of endothelial dysfunction, such as endocan in patients with type 2 diabetes mellitus (T2D), since there are no studies concerning this issue. PATIENTS AND METHODS: This case-control study included a total of 42...
OBJECTIVE: PCOS is the most common endocrinopathy among reproductive age women. Approximately 60% of PCOS women have insulin resistance. While the efficacy of metformin in reducing insulin resistance and decreasing androgen level has been widely validated, there is no agreement on the dose of metformin to be used. PATIENTS AND METHODS: Prospective non-randomized cohort study of 108 insulin resistant, overweight and obese PCOS women, aged between 22 and 35 years. All patients received 1500 mg of...
OBJECTIVE: Diabetic foot ulcer (DFU) is a serious chronic complication leading to disability and death in patients suffering from diabetes. Currently, there is no effective marker for its early diagnosis. The aim of this study is to analyze the difference of circRNA expression profiles between DFU and normal human wounds (NHW) and to screen serum biomarkers for the early diagnosis of DFU. MATERIALS AND METHODS: Differentially expressed circRNAs were screened by bioinformatics analysis, using GSE114248...
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Spontaneous Regression of HCC- When the Immune System Stands Up to Cancer. Hepatology. 2020 Aug 02;: Authors: Arjunan V, Hansen A, Deutzmann A, Sze DY, Dhanasekaran R Abstract Spontaneous regression of cancer is rare and has been observed mostly in immunogenic cancers like melanoma. A few cases of spontaneous regression of hepatocellular carcinoma (HCC) have been reported, but the mechanisms of regression have not been elucidated. Here, we...
A Rare Case of Vulvar Superficial Angiomyxoma in a Pediatric Patient. J Pediatr Adolesc Gynecol. 2020 Jul 30;: Authors: O'Flynn O'Brien KL, Cortes-Santiago N, Patil NM, Bercaw-Pratt JL Abstract BACKGROUND: Superficial angiomyxoma (SAM) is a rare, benign cutaneous tumor. Originally described as a component of Carney Complex, it is now recognized as a sporadic condition. CASE: A 7-year-old female was referred for management of a 2.5...
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Abstract Introduction The aim of this study was to assess the qualitative and MRI findings of renal tumours, to determine which lesions contain microscopic fat, one of the potential differentiating factors between tumour types. Methods 73 patients who underwent 3 Tesla MRI including chemical shift imaging, with subsequent biopsy or excision for histopathological diagnosis, were included in the study. The images were reviewed for a decrease in signal intensity (SI) on the opposed phase compared...
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Antiviral Chemistry and Chemotherapy, Volume 28, Issue , January-December 2020. Respiratory Syncytial Virus is a yearly respiratory virus that causes significant frequencies of morbidities, particularly in the young and elderly populations. However, preventive vaccines and/or treatment therapies are generally lacking, although much attention is now being placed on this virus. Moreover, there are now multiple strategies currently being explored in a race to the first licensed vaccine. While vaccines...
Sun Aug 02, 2020 14:01
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Abstract Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischemic stroke. Methods 664 home‐dwelling participants in the Norwegian Cognitive Impairment After Stroke study, a multicenter observational study, were evaluated 3 and 18 months post‐stroke. We assessed medication adherence by self‐reporting (4‐item Morisky Medication Adherence...
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This study recruited 15 patients with gastroparesis (13 diabetic) who were given prucalopride 4 mg daily or placebo for 4 weeks in a randomized, double‐blind, placebo‐controlled crossover design. The primary outcome measures of symptoms were not different between groups. However, gastric emptying and bowel movement frequency were accelerated with prucalopride. The medication was well tolerated. Further study with larger sample sizes, and/or dose adjustment, is warranted. Abstract Background...
Chronic stress increases levels of pro‐inflammatory cytokines, decreases GR transcriptional binding at epithelia cell tight junction gene promoters reducing tight junction gene expression, culminating in increased paracellular permeability and enhanced visceral pain sensation. Methylation of the repressive histone H3K9me2/me3 plays a central role in this process. Abstract Background Chronic stress is associated with activation of the HPA axis, elevation in pro‐inflammatory cytokines,...
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Abstract Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by rapidly progressing necrolytic ulceration of the skin. Proper treatment is crucial since it can result in devastating consequences. First‐line treatments include systemic corticosteroids or cyclosporine. However, no standardized treatment regimens for refractory cases exist and treatment outcomes are affected by underlying conditions. PG after cesarean section, which is believed to occur in association with underlying...
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Abstract To observe the inflammatory response, differentiation of Th17/Treg subsets and apoptosis of lymphocytes, by regulating miR-126 in lymphocytes of septic rats. After using cecal ligation and puncture to establish sepsis model, miR-126 mimic and miR-126 inhibitor were used to transfect lymphocytes of septic rats in vitro and in vivo. ELISA was used to detect TNF-α, IL-6, IL-17, and IL-10, the differentiation of Th17 and Treg was...
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Summary The current SARS‐CoV‐2 pandemic particularly endangers older people with pre‐existing cardiopulmonary and metabolic conditions. However, it is also currently under discussion whether patients under immunosuppressive therapy also have a higher risk of suffering a severe course of the COVID‐19 disease. In principle though, there is currently no data available for a general reduction or pause of immunosuppression in patients with autoimmune diseases because of the SARS‐CoV‐2 pandemic. However,...
Sun Aug 02, 2020 21:26
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Abstract Purpose There is no enough evidence present on the success of single implant‐retained mandibular overdentures (SIMO) with Dalla Bona and Locator attachments. This study aims to compare crestal bone loss and patient satisfaction with SIMO with Dalla Bona and Locator attachment following immediate loading protocols. Material and Methods Twelve patients included in Group 1 received immediate SIMO with Dalla Bona attachments, and another twelve patients in Group 2 received immediate...
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Abstract Sleep and depression are interlinked throughout the lifespan, but very few studies have examined the directionality of the sleep–depression link in children. The aim of the current study was to prospectively examine the bidirectional association between sleep problems and internalizing problems and depressive symptoms in toddlers and children aged 1.5 and 8 years. Data stem from the large ongoing population‐based longitudinal study, the Norwegian Mother, Father and Child Cohort Study, recruited...
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