Cancers, Vol. 12, Pages 2149: Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo Cancers doi: 10.3390/cancers12082149 Authors: Kimberley C. Clark Duncan R. Hewett Vasilios Panagopoulos Natalya Plakhova Khatora S. Opperman Alanah L. Bradey Krzysztof M. Mrozik Kate Vandyke Siddhartha Mukherjee Gareth C.G. Davies Daniel L. Worthley Andrew C.W. Zannettino In most instances, multiple myeloma...
Cancers, Vol. 12, Pages 2148: lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System Cancers doi: 10.3390/cancers12082148 Authors: Dominik A. Barth Jaroslav Juracek Ondrej Slaby Martin Pichler George A. Calin Available systemic treatment options for cancers of the genitourinary system have experienced great progress in the last decade. However, a large proportion of patients eventually develop resistance to treatment, resulting in disease progression...
Cancers, Vol. 12, Pages 2150: The Perfect Combination: Enhancing Patient Response to PD-1-Based Therapies in Epithelial Ovarian Cancer Cancers doi: 10.3390/cancers12082150 Authors: Nicole E. James Morgan Woodman Paul A. DiSilvestro Jennifer R. Ribeiro Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, with an overall 5-year survival of only 47%. As the development of novel targeted therapies is drastically necessary in order to improve patient survival,...
Cancers, Vol. 12, Pages 2146: Impact of Grip Strength in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib Cancers doi: 10.3390/cancers12082146 Authors: Kei Endo Hidekatsu Kuroda Jo Kanazawa Takuro Sato Yudai Fujiwara Tamami Abe Hiroki Sato Youhei Kooka Takayoshi Oikawa Kei Sawara Yasuhiro Takikawa Although sarcopenia is characterized by a loss of muscle strength and skeletal muscle mass, few studies have evaluated the effect of...
Cancers, Vol. 12, Pages 2147: Stable Isotope Tracing Metabolomics to Investigate the Metabolic Activity of Bioactive Compounds for Cancer Prevention and Treatment Cancers doi: 10.3390/cancers12082147 Authors: Feroza K. Choudhury G. Lavender Hackman Alessia Lodi Stefano Tiziani A major hallmark of cancer is the metabolic reprogramming of cancer cells to fuel tumor growth and proliferation. Various plant-derived bioactive compounds efficiently target the metabolic vulnerabilities...
Cancers, Vol. 12, Pages 2145: MR1-Restricted T Cells in Cancer Immunotherapy Cancers doi: 10.3390/cancers12082145 Authors: Pedro Flores-Villanueva Navid Sobhani Xu Wang Yong Li Major histocompatibility complex class I-related (MR1) was first identified as a cell membrane protein involved in the development and expansion of a unique set of T cells expressing an invariant T-cell receptor (TCR) α-chain. These cells were initially discovered in mucosal tissues, such as...
Cancers, Vol. 12, Pages 2144: Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death Cancers doi: 10.3390/cancers12082144 Authors: Anna-Luisa Luger Nadja I. Lorenz Hans Urban Iris Divé Anna L. Engel Florian Strassheimer Katja Dettmer Pia S. Zeiner Shabnam Shaid Nina Struve Malte Kriegs Ute Hofmann Peter J. Oefner Patrick N. Harter Joachim P. Steinbach Michael W. Ronellenfitsch Background:...
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Cells, Vol. 9, Pages 1830: NDAT Targets PI3K-Mediated PD-L1 Upregulation to Reduce Proliferation in Gefitinib-Resistant Colorectal Cancer Cells doi: 10.3390/cells9081830 Authors: Tung-Yung Huang Tung-Cheng Chang Yu-Tang Chin Yi-Shin Pan Wong-Jin Chang Feng-Cheng Liu Ema Dwi Hastuti Shih-Jiuan Chiu Shwu-Huey Wang Chun A. Changou Zi-Lin Li Yi-Ru Chen Hung-Ru Chu Ya-Jung Shih R. Holland Cheng Alexander Wu Hung-Yun Lin Kuan Wang Jacqueline...
Cells, Vol. 9, Pages 1827: Tat-Cannabinoid Receptor Interacting Protein Reduces Ischemia-Induced Neuronal Damage and Its Possible Relationship with 14-3-3η Cells doi: 10.3390/cells9081827 Authors: Hyun Jung Kwon Duk-Soo Kim Woosuk Kim Hyo Young Jung Yeon Hee Yu Young In Ju Dae-Kyoon Park In Koo Hwang Dae Won Kim Dae Young Yoo Cannabinoid receptor-interacting protein 1a (CRIP1a) binds to the C-terminal domain of cannabinoid 1 receptor (CB1R) and regulates CB1R...
Cells, Vol. 9, Pages 1828: Gene Expression Clustering and Selected Head and Neck Cancer Gene Signatures Highlight Risk Probability Differences in Oral Premalignant Lesions Cells doi: 10.3390/cells9081828 Authors: Andrea Carenzo Mara S. Serafini Elisa Roca Alberto Paderno Davide Mattavelli Chiara Romani Pierre Saintigny Senada Koljenović Lisa Licitra Loris De Cecco Paolo Bossi Background: Oral premalignant lesions (OPLs) represent the most common oral precancerous...
Cells, Vol. 9, Pages 1826: Overexpression of Extradomain-B Fibronectin is Associated with Invasion of Breast Cancer Cells Cells doi: 10.3390/cells9081826 Authors: Amita Vaidya Helen Wang Victoria Qian Hannah Gilmore Zheng-Rong Lu Breast tumor heterogeneity is a major impediment to oncotherapy. Cancer cells undergo rapid clonal evolution, thereby acquiring significant growth and invasive advantages. The absence of specific markers of these high-risk populations precludes efficient...
Cells, Vol. 9, Pages 1829: Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells Cells doi: 10.3390/cells9081829 Authors: Nazli Güllü Dennis Kobelt Hassan Brim Shaman Rahman Lena Timm Janice Smith Akbar Soleimani Stefano Di Marco Silvia Bisti Hassan Ashktorab Ulrike Stein The high mortality rate of colorectal cancer (CRC) patients is directly associated with metastatic dissemination. However, therapeutic...
Cells, Vol. 9, Pages 1825: Cardiomyocyte Transplantation after Myocardial Infarction Alters the Immune Response in the Heart Cells doi: 10.3390/cells9081825 Authors: Praveen Vasudevan Markus Wolfien Heiko Lemcke Cajetan Immanuel Lang Anna Skorska Ralf Gaebel Dirk Koczan Tobias Lindner Robby Engelmann Brigitte Vollmar Bernd Joachim Krause Olaf Wolkenhauer Hermann Lang Gustav Steinhoff Robert David We investigated the influence of syngeneic cardiomyocyte...
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Challenges, Vol. 11, Pages 17: Operating Small Hydropower Plants in Greece under Intermittent Flow Uncertainty: The Case of Tsiknias River (Lesvos) Challenges doi: 10.3390/challe11020017 Authors: Ourania Tzoraki In arid and semi-arid parts of the world, river exploitation is intensive, involving water storage for irrigation or hydropower generation. In Greece, 100 small hydropower plants (SHPs) take advantage of less than 10% of the hydropower potential of low flow streams (<2...
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Chemosensors, Vol. 8, Pages 62: Study on Ultrasonic Assisted Electrochemical Drill-Grinding of Superalloy Chemosensors doi: 10.3390/chemosensors8030062 Authors: Huanghai Kong Yong Liu Xiangming Zhu Tengfei Peng Electrochemical grinding (ECG) technique composed of electrochemical machining (ECM) and mechanical grinding is a proper method for machining of difficult-to-cut alloys. This paper presents a new ultrasonic assisted electrochemical drill-grinding (UAECDG) technique which...
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Children, Vol. 7, Pages 88: Large Splenic Abscess Caused by Non-Typhoidal Salmonella in a Healthy Child Treated with Percutaneous Drainage Children doi: 10.3390/children7080088 Authors: Hyun Woo Lee Seung Beom Han Splenic abscess occurs very rarely in healthy children. Although typhoid fever was the leading cause of splenic abscess in the pre-antibiotic era, Salmonella spp. remain to be the major pathogens causing splenic abscess, with an increasing worldwide frequency of splenic...
Children, Vol. 7, Pages 87: Neonatal COVID-19 Pneumonia: Report of the First Case in a Preterm Neonate in Mayotte, an Overseas Department of France Children doi: 10.3390/children7080087 Authors: Soumeth Abasse Laila Essabar Tereza Costin Voninavoko Mahisatra Mohamed Kaci Axelle Braconnier Roger Serhal Louis Collet Abdallah Fayssoil We report the first case of COVID-19 pneumonia in a preterm neonate in Mayotte, an overseas department of France. The newborn developed...
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Cosmetics, Vol. 7, Pages 63: Salicylate UV-Filters in Sunscreen Formulations Compromise the Preservative System Efficacy against Pseudomonas aeruginosa and Burkholderia cepacia Cosmetics doi: 10.3390/cosmetics7030063 Authors: Noa Ziklo Inbal Tzafrir Regina Shulkin Paul Salama Contamination of personal-care products are a serious health concern and therefore, preservative solutions are necessary for the costumers’ safety. High sun protection factor (SPF) sunscreen formulations...
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Dentistry Journal, Vol. 8, Pages 85: Comparison of Postoperative Bleeding between Application of Polyglycolic Acid Sheet and Primary Closure in Tongue Cancer Patients with Partial Glossectomy Dentistry Journal doi: 10.3390/dj8030085 Authors: Satoshi Fukuzawa Kenji Yamagata Yuuma Hasegawa Naomi Ishibashi-Kanno Fumihiko Uchida Toru Yanagawa Hiroki Bukawa The technique of covering a mucosal defect with fibrin glue and a polyglycolic acid sheet (MCFP) for the resection...
Dentistry Journal, Vol. 8, Pages 83: Potential Co-Factors of an Intraoral Contact Allergy—A Cross-Sectional Study Dentistry Journal doi: 10.3390/dj8030083 Authors: Constanze Olms Jana Schor Maryam Yahiaoui-Doktor The aim of this cross-sectional study was to evaluate the frequency of dental allergens and potential co-factors, especially hypothyroidism, for patients with an intraoral contact allergy. From 2015 to 2016, patients with confirmed symptoms of an intraoral contact allergy...
Dentistry Journal, Vol. 8, Pages 84: The Association between D-Dimer and Prognosis in the Patients with Oral Cancer Dentistry Journal doi: 10.3390/dj8030084 Authors: Kenji Yamagata Satoshi Fukuzawa Naomi Ishibashi-Kanno Fumihiko Uchida Toru Yanagawa Hiroki Bukawa D-dimer levels are reported to relate with tumor stage, prognosis, and lymph node involvement, as well as overall survival (OS) in patients with solid tumors. The purpose of this study was to investigate association...
Dentistry Journal, Vol. 8, Pages 82: Developing Person-Centred Dental Care: The Perspectives of People Living in Poverty Dentistry Journal doi: 10.3390/dj8030082 Authors: Nioushah Noushi Christophe Bedos Dentistry has seen a slow trend toward person-centred care (PCC), with most approaches developed by scholars who have tried to progress away from disease-centred care. Unfortunately, the perspectives and experiences of underprivileged people have not been considered in the development...
Dentistry Journal, Vol. 8, Pages 81: Imaging Software Programs for Reliable Mathematical Measurements in Orthodontics Dentistry Journal doi: 10.3390/dj8030081 Authors: Eman Saad Radwan Andrea Scribante Maria Francesca Sfondrini Mona A Montasser Aim: To evaluate the reliability of linear and angular measurements taken using different software programs in orthodontics. Materials and Methods: A sample of four software programs from different manufacturers, namely MicroDicom viewer,...
Dentistry Journal, Vol. 8, Pages 80: Prevalence of Peri-Implantitis: A Multi-Centered Cross-Sectional Study on 248 Patients Dentistry Journal doi: 10.3390/dj8030080 Authors: Tommaso Weinstein Tommaso Clauser Massimo Del Fabbro Matteo Deflorian Andrea Parenti Silvio Taschieri Tiziano Testori Luca Francetti The aim of this multicenter cross-sectional study was to determine the prevalence of peri-implantitis and to assess its association with several patient- and implant-related...
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Diagnostics, Vol. 10, Pages 553: Ultrasound Features of a Uterine Perivascular Epithelioid Cell Tumor (PEComa): Case Report and Literature Review Diagnostics doi: 10.3390/diagnostics10080553 Authors: Luca Giannella Giovanni Delli Carpini Nina Montik Valeria Verdecchia Francesca Puccio Jacopo Di Giuseppe Dimitrios Tsiroglou Gaia Goteri Andrea Ciavattini Background: Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal tumors. One of the most frequent...
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Diversity, Vol. 12, Pages 303: AFLP-Based Analysis of Variation and Population Structure in Mutagenesis Induced Faba Bean Diversity doi: 10.3390/d12080303 Authors: Nurmansyah Nurmansyah Salem S. Alghamdi Hussein M. Migdadi Muhammad A. Khan Muhammad Afzal Genetic diversity enrichment is urgently necessary to develop climate-resilient faba bean cultivars. The present study aimed to measure the enrichment of genetic diversity and changes in the population structure of faba bean,...
Diversity, Vol. 12, Pages 302: Effects of Human Activities on the Diversity of Waterbirds Wintering in a Shallow Lake of the Middle and Lower Yangtze River Floodplain, China Diversity doi: 10.3390/d12080302 Authors: Xinjian Wang Jinyun Chen Lizhi Zhou Human activity is the major factor driving the wetland degradation in shallow lakes. Human exploitation of lake wetlands alters the habitats of wintering waterbirds, and, in turn, waterbird diversity in the shallow lakes. In the present...
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Environments, Vol. 7, Pages 59: From Boiling to Frozen? The Rise and Fall of International Tourism to Iceland in the Era of Overtourism Environments doi: 10.3390/environments7080059 Authors: Anna Dóra Sæþórsdóttir C. Michael Hall Margrét Wendt Overtourism has emerged as a common concept to describe the perceived negative impacts that large numbers of tourists can have on destinations. Iceland is one of the destinations which has been most associated with the concept of overtourism....
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Epigenomes, Vol. 4, Pages 16: Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease Epigenomes doi: 10.3390/epigenomes4030016 Authors: Sebastian-delaCruz Olazagoitia-Garmendia Gonzalez-Moro Santin Garcia-Etxebarria Castellanos-Rubio Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract that develops due to the interaction between genetic and environmental factors. More than 160 loci have been...
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Foods, Vol. 9, Pages 1049: Comparison of Real-Time PCR Quantification Methods in the Identification of Poultry Species in Meat Products Foods doi: 10.3390/foods9081049 Authors: Kerstin Dolch Sabine Andrée Fredi Schwägele Poultry meat is consumed worldwide and is prone to food fraud because of large price differences among meat from different poultry species. Precise and sensitive analytical methods are necessary to control poultry meat products. We chose species–specific...
Foods, Vol. 9, Pages 1047: Serving Temperatures of Best-Selling Coffees in Two Segments of the Brazilian Food Service Industry Are “Very Hot” Foods doi: 10.3390/foods9081047 Authors: Ian C. C. Nóbrega Igor H. L. Costa Axel C. Macedo Yuri M. Ishihara Dirk W. Lachenmeier The International Agency for Research on Cancer has classified the consumption of “very hot” beverages (temperature >65 °C) as “probably carcinogenic to humans”,...
Foods, Vol. 9, Pages 1048: Growth Potential of Listeria monocytogenes in Three Different Salmon Products Foods doi: 10.3390/foods9081048 Authors: Corinne Eicher Andres Ruiz Subira Sabrina Corti Arnulf Meusburger Roger Stephan Claudia Guldimann Cold smoked salmon and sushi salmon have been implicated in outbreaks of listeriosis. We performed challenge tests and a durability study with Listeria monocytogenes on different salmon products to determine the growth potential...
Foods, Vol. 9, Pages 1046: Quality of Chicken Fat by-Products: Lipid Profile and Colour Properties Foods doi: 10.3390/foods9081046 Authors: Lina María Peña-Saldarriaga Juana Fernández-López José Angel Pérez-Alvarez The growth in the production and consumption of chicken meat and related products is responsible for the formation a large number of by-products. Among these, abdominal and gizzard fat is usually considered as waste and thus is discarded, creating an environmental problem....
Foods, Vol. 9, Pages 1045: Dietary Components, Microbial Metabolites and Human Health: Reading between the Lines Foods doi: 10.3390/foods9081045 Authors: Yao Guo Xiaohan Bian Jiali Liu Ming Zhu Lin Li Tingyu Yao Congjia Tang Vinothkannan Ravichandran Peng Liao Konstantinos Papadimitriou Jia Yin Trillions of bacteria reside in the human gut and they metabolize dietary substances to obtain nutrients and energy while producing metabolites. Therefore, different...
Foods, Vol. 9, Pages 1044: Towards More Sustainable Meat Products: Extenders as a Way of Reducing Meat Content Foods doi: 10.3390/foods9081044 Authors: Tatiana Pintado Gonzalo Delgado-Pando The low efficiency of animal protein (meat products) production is one of the main concerns for sustainable food production. However, meat provides high-quality protein among other compounds such as minerals or vitamins. The use of meat extenders, non-meat substances with high protein content,...
Foods, Vol. 9, Pages 1043: Simultaneous Optimization of Acetaldehyde and DMS Concentrations for Better Sensory Quality of Beer Fermented on an Industrial Scale Foods doi: 10.3390/foods9081043 Authors: Krzysztof Kucharczyk Krzysztof Żyła Tadeusz Tuszyński The levels of selected volatile components that affected the sensory properties of a lager beer were optimized under high-gravity brewing conditions (15.5 °P) in an industrial plant. The influence of different pitching...
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Healthcare, Vol. 8, Pages 253: Low Disclosure Rates to Sexual Partners and Unsafe Sexual Practices of Youth Recently Diagnosed with HIV; Implications for HIV Prevention Interventions in South Africa Healthcare doi: 10.3390/healthcare8030253 Authors: Khensane Mengwai Sphiwe Madiba Perpetua Modjadji The study investigated the motivation to disclose or the decision to withhold one’s HIV serostatus to one’s partners and assessed the implications of non-disclosure...
Healthcare, Vol. 8, Pages 252: Expanding Pharmacotherapy Data Collection, Analysis, and Implementation in ERAS® Programs—The Methodology of an Exploratory Feasibility Study Healthcare doi: 10.3390/healthcare8030252 Authors: Eric Johnson Richard Parrish II Gregg Nelson Kevin Elias Brian Kramer Marian Gaviola Surgical organizations dedicated to the improvement of patient outcomes have led to a worldwide paradigm shift in perioperative patient care. Since 2012, the Enhanced...
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Humanities, Vol. 9, Pages 72: The Blue Cultural Fix: Water-Spirits and World-Ecology in Jorge Amado’s Mar Morto and Pepetela’s O Desejo de Kianda Humanities doi: 10.3390/h9030072 Authors: Thomas Waller Putting Blue Humanities scholarship in critical dialogue with recent research on the ‘cultural fix’ and ‘fixed-labour-power’, this article offers a comparative reading of two Portuguese-language novels in which the figure of the female water-spirit...
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