Abstract Objective To investigate the efficacy of sclerotherapy with monoethanolamine oleate (MEO) in a series of cases of benign oral vascular lesions (BOVL). Material and methods Clinical records and images were retrieved (2015–2019), and data regarding age, gender, location, size, symptomatology, treatment and outcomes of patients were collected. All patients...
Abstract Objectives To study the association between anticholinergic burden and oral hygiene practices and oral hygiene status among 46-year-old people. Materials and methods The study included 1945 participants from the Northern Finland Birth Cohort 1966 (NFBC1966), who had a complete dental status. The participants underwent clinical medical and dental...
Abstract Objective To compare the clinical behavior of a universal light-curing, ultra-fine particle hybrid composite and successor of this material in class I and II cavities after 60 months. Materials and methods Forty patients (21 females, 19 males) with ages ranging between 18 and 38 years (23.15 ± 5.15) received 80 (13 Cl I and 67 Cl II) resin composite...
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Publication date: Available online 3 August 2020Source: Dental MaterialsAuthor(s): Leina Nakanishi, Marina R. Kaizer, Suzane Brandeburski, Sergio S. Cava, Alvaro Della Bona, Yu Zhang, Rafael R. Moraes
Publication date: Available online 2 August 2020Source: Dental MaterialsAuthor(s): Luis Felipe J. Schneider, Robson Barroso Ribeiro, Walleska Feijó Liberato, Vinícius Esteves Salgado, Rafael R. Moraes, Larissa Maria Cavalcante
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In this study, the cytotoxicity of different combinations of contemporary resin‐based restoratives (adhesives, composites, luting agents) against human keratinocytes (HaCaT) was evaluated under two conditions, whether materials were applied to dentin or not. Adhesives (3‐step etch‐and‐rinse/3ER: OptiBond FL; 2‐step self‐etch/2SE Clearfil SE Bond; Single Bond Universal/UNI), composites (conventional composite resin/CCR: Filtek Z350XT; flowable/FCR: Filtek Z350XT Flow; self‐adhesive composite resin/SACR:...
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We read with great interest the first report on PANSOFOS in head and neck using 3D printing technology.1
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Publication date: Available online 2 August 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): K.A. Sakran, R. Liu, T. Yu, R.K. Al-Rokhami, D. He
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Publication date: Available online 2 August 2020Source: Archives of Oral BiologyAuthor(s): Wan Nur Fatihah Wan Mohd Kamaluddin, Nurul Alia Risma Rismayuddin, Ahmad Faisal Ismail, Edre Mohamad Aidid, Noratikah Othman, Noor Afifah Hanin Mohamad, Mohd Hafiz Arzmi
Publication date: Available online 2 August 2020Source: Archives of Oral BiologyAuthor(s): Isabelly de Carvalho Leal, Wlhadya Kaenny De Freitas Costa, Vanara Florêncio Passos
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Abstract Background Oral squamous cell carcinoma (OSCC) is a lethal and deforming disease of rising incidence. With poor 5‐year survival rates associated with higher stage disease, there is a need in clinical practice for reliable prognostic determinants to consolidate treatment planning and coordinate therapeutic approaches to improve long‐term clinical outcomes for patients. Methods A retrospective clinico‐pathological review of 467 OSCC patients with documented clinical outcome and treated...
Abstract Background A large number of oral squamous cell carcinomas (OSCCs) are believed to be preceded by oral potentially malignant disorders (OPMD) that have an increased likelihood of malignant transformation compared to clinically normal mucosa. This study was performed to identify differentially expressed genes between OPMDs that underwent malignant transformation (MT) and those that did not, termed ‘non‐transforming’ (NT) cases. Methods Total RNA was extracted from formalin‐fixed...
Abstract Background Although association between oral squamous cell carcinoma (OSCC) with epithelial–mesenchymal transition (EMT) has been demonstrated, we found CD147, one transmembrane protein we previously studied in oral submucous fibrosis was correlated with E‐cadherin, one marker of EMT. Here, we investigated CD147 expression in the different stages of OSCC and assessed its association with epithelial–mesenchymal transition (EMT). Materials and methods CD147 and E‐cadherin expression...
Abstract Background The natural history of oral squamous cell carcinoma (OSCC) is complicated by progressive disease including loco‐regional tumour recurrence and development of distant metastases. Accurate prediction of tumour behaviour is crucial in delivering individualized treatment plans and developing optimal patient follow‐up and surveillance strategies. Machine learning algorithms may be employed in oncology research to improve clinical outcome prediction. Methods Retrospective...
Abstract Background Emerging evidence indicates that CCN1 is a novel inflammation‐regulated mediator involved in the pathogenesis of some immune‐mediated inflammatory diseases. The objective of this study was to investigate the preliminary roles of CCN1 and it related cytokines IL‐1β, CCL5, and ICAM1 in oral lichen planus (OLP). Methods CCN1 expression levels in biopsies from OLP patients against normal oral mucosa (NOM) using immunohistochemistry (42 OLP vs 9 NOM) and RT‐qPCR (20 OLP vs...
Abstract Objectives The present study investigated the correlation between the expression of DNA methyltransferase (DNMT) 1, 3A and 3B and the proliferation of mucoepidermoid carcinomas (MECs) using the molecular markers Ki‐67 and Cyclin D1. This study also demonstrates the effects of 5‐aza‐2‐deoxycytidine (5AC) on the MEC tumor cell lines in relation to DNMT1 and 3A expression, and cell cycle arrest. Material and Methods The immunohistochemistry of DNMT1, DNMT3A, DNMT3B, Ki‐67, and Cyclin...
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Publication date: Available online 2 August 2020Source: The Journal of Prosthetic DentistryAuthor(s): Sumanth K. Veeraganta, Abdulaziz Samran, Sebastian Wille, Matthias Kern
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