Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-17967-yThe correct identification of copy-number aberrations (CNAs) in tumours can provide information for diagnosis, prognosis and therapeutic strategies. Here, the authors provide an algorithm, HATCHet, which quantifies CNAs using multiple samples from the same patient, providing more accurate information than studying one sample alone.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-17197-2Cell groups in the hypothalamic suprachiasmatic clock contribute to the genesis of circadian rhythms. The authors identified two populations of vasoactive intestinal polypeptide-expressing neurons in the suprachiasmatic nucleus which regulate locomotor circadian rhythm in mice.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18236-8Bacteriophages and their hosts are involved in a constant evolutionary arms race that should lead to divergence between phage genes over time. Here, the authors recruit metagenomic reads to virus reference genomes and genome fragments in samples from cryoconite holes and show that phages with near-identical core genomes maintain diversity by possession of numerous flexible gene modules, where homologous genes...
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18332-9Bayesian brain theories suggest that perception, action and cognition arise as animals minimise the mismatch between their expectations and reality. This principle could unify cognitive science with the broader natural sciences, but leave key elements of cognition and behaviour unexplained.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18238-6Wearable biosensors have been used successfully for biomarker analysis, however, a lack of control over sampling limits applications. Here, the authors report a programmable microfluidic valve to control flow rate, sampling times and allow for biofluid routing and compartmentalisation.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18149-6SARS-CoV-2 mainly transmits via respiratory droplets. Here Deng et al. show that SARS-CoV-2 can infect rhesus macaques via ocular conjunctival inoculation.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-17779-0Conservation biologists often assume that rare (or less abundant) species are more likely to be declining under anthropogenic change. Here, the authors synthesise population trend data for ~2000 animal species to show that population trends cover a wide spectrum of change from losses to gains, which are not related to species rarity.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18069-5Avr2 is an effector secreted by the phytopathogen Cladosporium fulvum to inhibit Rcr3, an apoplastic protease of solanaceous plants. Here the authors show that this interaction predates the emergence of Cf-2, an R-gene that evolved in Solanum to co-opt an existing effector-target reaction and trigger resistance.
Wed Sep 02, 2020 03:00
Nature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-18079-3Publisher Correction: Evolution of generalist resistance to herbicide mixtures reveals a trade-off in resistance management
Wed Sep 02, 2020 03:00
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