Clinical outcome in recurrent and/or metastatic head and neck cancer patients after discontinuation of nivolumab monotherapy due to immune-related adverse events. Acta Otolaryngol. 2020 Aug 18;:1-6 Authors: Yasumatsu R, Matsuo M, Wakasaki T, Masuda M, Takeuchi T, Manako T, Jiromaru R, Uchi R, Hashimoto K, Nakagawa T Abstract BACKGROUND: Significant immune-related adverse events (irAEs) requiring therapy discontinuation sometimes occur....
Wed Aug 19, 2020 13:07
Current and emerging pharmacotherapy for pediatric allergic rhinitis. Expert Opin Pharmacother. 2020 Aug 18;:1-7 Authors: Tomazic PV, Lang-Loidolt D Abstract INTRODUCTION: Allergic rhinitis (AR) is a global health problem in adults as well as the younger population, continuously increasing and posing a significant problem for patients, health care systems and economies. For the younger population, some aspects differ from treatment of...
Wed Aug 19, 2020 13:07
Lymph node ratio as a prognostic marker of oral tongue squamous cell carcinoma: a cohort study. Ann R Coll Surg Engl. 2020 Aug 18;:1-7 Authors: Iftikhar H, Rozi S, Zahid N, Awan MS, Nathani KR Abstract INTRODUCTION: Lymph node metastasis is a poor prognostic indicator and is well established in tongue squamous cell carcinoma. Based on the current staging system, accurate risk stratification is difficult. There is thus a need to evaluate...
Wed Aug 19, 2020 13:07
Malignant Otitis External: Our Experience and Literature Review. Am J Case Rep. 2020 Aug 18;21:e925060 Authors: Di Lullo AM, Russo C, Piroli P, Petti A, Capriglione P, Cantone E, Motta G, Iengo M, Elefante A, Cavaliere M Abstract BACKGROUND Malignant external otitis (MEO) is an invasive infection that can involve the external auditory canal and the skull base up to the contiguous soft tissues. Considering the changing face of MEO, we reviewed...
Wed Aug 19, 2020 13:07
Assessment of the New L Pharyngeal Flap for Velopharyngeal Insufficiency. Cleft Palate Craniofac J. 2020 Aug 18;:1055665620950150 Authors: El-Anwar MW, Elsheikh E, Alnemr MA, Quriba AS, Hassan E, Bahgat AY Abstract OBJECTIVE: To assess the results of the new L pharyngeal flap for treatment of velopharyngeal insufficiency (VPI). METHODS: This study included 60 patients who were diagnosed as persistent VPI (for > 1 year without...
Wed Aug 19, 2020 13:07
The role of upper GI flexible endoscopy in management of large pharyngeal pouches. Clin Otolaryngol. 2020 Aug 17;: Authors: Ravisankar S, Shahsavari S, Manickavasagam J, Majumdar S, Patil P Abstract Pharyngeal pouch operations are commonly performed in ENT. However, some pouches can be large, with poor access making surgical management more complex. PMID: 32808445 [PubMed - as supplied by publisher]
Wed Aug 19, 2020 13:07
Predictive value of CD8/FOXP3 ratio combined with PD-L1 expression for radiosensitivity in patients with squamous cell carcinoma of the larynx receiving definitive radiation therapy. Head Neck. 2020 Aug 18;: Authors: Ono T, Azuma K, Kawahara A, Kakuma T, Sato F, Akiba J, Tanaka N, Abe T, Chitose SI, Umeno H Abstract BACKGROUND: Little is known about immune-related radiosensitivity in patients with squamous cell carcinoma of the larynx...
Wed Aug 19, 2020 13:07
Effect of monoclonal antibody drug therapy on mucosal biomarkers in airway disease: a systematic review. Clin Exp Allergy. 2020 Aug 17;: Authors: Walter S, Ho J, Alvarado R, Rimmer J, Campbell R, Kalish L, Sacks R, Harvey RJ Abstract BACKGROUND: Monoclonal antibody therapies have a growing role in treating refractory airway disease. OBJECTIVE: The review aimed to summarise the response of respiratory mucosa to monoclonal antibody...
Wed Aug 19, 2020 13:07
Curative-intent radiotherapy for glottic carcinoma in situ. Head Neck. 2020 Aug 17;: Authors: Mendenhall WM, Morris CG, Amdur RJ, Hitchcock KE, Cheddha N, Dziegielewski PT Abstract BACKGROUND: The aim of the study was to update our experience treating patients with glottic carcinoma in situ (CIS) with curative radiotherapy (RT). METHODS: Fifty patients received continuous-course RT using once-daily fractionation. Twenty-eight...
Wed Aug 19, 2020 13:07
Keys to successful implementation of routine symptom monitoring in head and neck oncology with "Healthcare Monitor" and patients' perspectives of quality of care. Head Neck. 2020 Aug 18;: Authors: Dronkers EAC, Baatenburg de Jong RJ, van der Poel EF, Sewnaik A, Offerman MPJ Abstract BACKGROUND: Value-based health care is increasingly used to facilitate a systematic approach during follow-up of patients. We developed Healthcare Monitor...
Wed Aug 19, 2020 13:07
Potential patient screening for late-onset Pompe disease in suspected sleep apnea: a rationale and study design for a Prospective Multicenter Observational Cohort Study in Japan (PSSAP-J Study). Sleep Breath. 2020 Aug 18;: Authors: Yamauchi M, Nakayama H, Shiota S, Ohshima Y, Terada J, Nishijima T, Kosuga M, Kitamura T, Tachibana N, Oguri T, Shirahama R, Aoki Y, Ishigaki K, Sugie K, Yagi T, Muraki H, Fujita Y, Takatani T, Muro S Abstract ...
Wed Aug 19, 2020 13:07
The Purification and Characterization of Exosomes from Macrophages. Methods Mol Biol. 2020;2184:77-90 Authors: Fridman E, Ginini L, Gil Z, Milman N Abstract Macrophages play an essential role in diverse biological processes, from the immune response to inflammatory and neurodegenerative disorders, to various cancers. A macrophage subpopulation, known as tumor-associated macrophages (TAMs), has been shown to promote tumorigenesis, metastasis,...
Wed Aug 19, 2020 13:07
Calcium channel blocker induced gingival enlargement following implant placement in a fibula free flap reconstruction of the mandible: a case report. Int J Implant Dent. 2020 Aug 18;6(1):47 Authors: Quach H, Ray-Chaudhuri A Abstract BACKGROUND: Gingival tissue enlargement is a common side effect of antiepileptic medications (e.g. phenytoin and sodium valproate), immunosuppressing drugs (e.g. cyclosporine) and calcium channel blockers (e.g....
Wed Aug 19, 2020 13:07
Prognostic Impact of Histologic Grade for Papillary Thyroid Carcinoma. Ann Surg Oncol. 2020 Aug 17;: Authors: Ho AS, Luu M, Barrios L, Balzer BL, Bose S, Fan X, Walgama E, Mallen-St Clair J, Alam U, Shafqat I, Lin DC, Chen Y, Van Eyk JE, Maghami EG, Braunstein GD, Sacks WL, Zumsteg ZS Abstract BACKGROUND: While numerous factors affect prognosis in papillary thyroid carcinoma (PTC), the comparative impact of histologic grade has not been...
Wed Aug 19, 2020 13:07
Momentary Analysis of Tinnitus: Considering the Patient. Curr Top Behav Neurosci. 2020 Aug 18;: Authors: Deutsch BC, Piccirillo JF Abstract Ecological momentary assessment is a valuable research technique meant to capture real-time data and contextualize disease. While more common in neuropsychiatric research, this methodology is exceptionally fit for tinnitus. Tinnitus has been shown to be affected by many patient-level and environment-specific...
Wed Aug 19, 2020 13:07
Head and neck radiotherapy amid the COVID-19 pandemic: practice recommendations of the Italian Association of Radiotherapy and Clinical Oncology (AIRO). Med Oncol. 2020 Aug 17;37(10):85 Authors: Alterio D, Volpe S, Bacigalupo A, Bonomo P, De Felice F, Dionisi F, D'Onofrio I, D'Angelo E, Di Rito A, Fanetti G, Franco P, Maddalo M, Merlotti A, Micciché F, Orlandi E, Paiar F, Ursino S, Pepa M, Corvò R, Di Muzio NG, Magrini SM, Russi E, Sanguineti G, Jereczek-Fossa...
Wed Aug 19, 2020 13:07
Emergency endovascular treatment of cavernous internal carotid artery acute bleeding with flow diverter stent: a single-center experience. Acta Neurochir (Wien). 2020 Aug 18;: Authors: Giorgianni A, Agosti E, Terrana A, Pozzi F, Sileo G, Nativo L, Balbi S, Motta A, Castelnuovo P, Locatelli D, Turri-Zanoni M Abstract BACKGROUND AND OBJECTIVE: To describe our single-center experience in the treatment of cavernous internal carotid artery...
Wed Aug 19, 2020 13:07
Effectiveness of diffusion-weighted imaging in predicting cervical lymph node metastasis in head and neck malignancies. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 11;: Authors: Zhou Y, Yu T, Rui X, Jin T, Huang Z, Huang Z Abstract OBJECTIVE: The aim of this study was to evaluate the effectiveness of diffusion-weighted imaging (DWI) in predicting cervical lymph node metastasis in head and neck malignancies. STUDY DESIGN:...
Wed Aug 19, 2020 13:07
Impact of the COVID-19 epidemic on ENT surgical volume. Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Aug 07;: Authors: Hervochon R, Atallah S, Levivien S, Teissier N, Baujat B, Tankere F Abstract PURPOSE: The purpose of this study was to assess the impact of the COVID-19 pandemic on the surgical volume of three ENT departments in Ile-de-France, a region severely affected by the epidemic. MATERIALS AND METHODS: The number and...
Wed Aug 19, 2020 13:07
[How a self-managed team can improve cohesion and communication during the patient's journey in a radiotherapy department: Experience of centre Jean-Bernard (Le Mans, France)]. Cancer Radiother. 2020 Aug 14;: Authors: Pasquier C, Gaudias C, Lepouzé O, Touchard C, Bombard S, Lafond C, Dupuis O Abstract Efficient communication between professionals is of upmost importance in improving treatment safety in a radiotherapy department, and is...
Wed Aug 19, 2020 13:07
Supraglottic subepithelial benign mass lesions: Focus on clinical features of sialolipoma-like lesion. Auris Nasus Larynx. 2020 Aug 14;: Authors: Tachibana T, Kariya S, Wani Y, Komatsubara Y, Naoi Y, Kuroda K, Fushimi S, Hotta M, Haruna K, Nagatani T, Makino T, Kataoka Y, Nishizaki K Abstract OBJECTIVES: Sialolipoma has been classified as a benign soft tissue lesion in the 2017 World Health Organization classification of head and neck...
Wed Aug 19, 2020 13:07
Positional obstructive sleep apnea in an obese pediatric population. J Clin Sleep Med. 2020 Aug 15;16(8):1295-1301 Authors: Selvadurai S, Voutsas G, Massicotte C, Kassner A, Katz SL, Propst EJ, Narang I Abstract STUDY OBJECTIVES: Positional obstructive sleep apnea (POSA) is a phenotype of obstructive sleep apnea (OSA) where sleep-related obstructive events occur predominantly in the supine position. Limited knowledge exists regarding the...
Wed Aug 19, 2020 13:07
Comparative Study of Endoscopic and Microscopic Type I Tympanoplasty in Terms of Delayed Facial Palsy. Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820945634 Authors: Li KH, Chan LP, Chen CK, Kuo SH, Wang LF, Chang NC, Wang HM, Ho KY, Chien CY Abstract OBJECTIVE: Delayed facial palsy is a complication of otologic surgery. Tympanoplasty is commonly employed in chronic otitis media. We compared the incidence and characteristics of delayed...
Wed Aug 19, 2020 13:07
Risk Factors for Laryngectomy for Dysfunctional Larynx After Organ Preservation Protocols: A Case-Control Analysis. Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820947702 Authors: Wu MP, Goldsmith T, Holman A, Kammer R, Parikh A, Devore EK, Emerick KS, Lin DT, Deschler DG, Richmon JD, Varvares MA, Naunheim MR Abstract OBJECTIVE: (1) To identify factors associated with severe dysfunctional larynx leading to total laryngectomy after curative...
Wed Aug 19, 2020 13:07
Nonopioid, Multimodal Analgesia as First-line Therapy After Otolaryngology Operations: Primer on Nonsteroidal Anti-inflammatory Drugs (NSAIDs). Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820947013 Authors: Cramer JD, Barnett ML, Anne S, Bateman BT, Rosenfeld RM, Tunkel DE, Brenner MJ Abstract OBJECTIVE: To offer pragmatic, evidence-informed advice on nonsteroidal anti-inflammatory drugs (NSAIDs) as first-line therapy after surgery....
Wed Aug 19, 2020 13:07
Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways. Antioxidants (Basel). 2020 Aug 12;9(8): Authors: Park JH, Shin JM, Yang HW, Kim TH, Lee SH, Lee HM, Cho JG, Park IH Abstract Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and tissue remodeling. The present study aimed to investigate the effects of cigarette smoke extract (CSE)...
Wed Aug 19, 2020 13:07
3D printing and characterization of human nasoseptal chondrocytes laden dual crosslinked oxidized alginate-gelatin hydrogels for cartilage repair approaches. Mater Sci Eng C Mater Biol Appl. 2020 Nov;116:111189 Authors: Schwarz S, Kuth S, Distler T, Gögele C, Stölzel K, Detsch R, Boccaccini AR, Schulze-Tanzil G Abstract As cartilage is one of the few tissues in the human body that is not vascularized, the body has very limited capabilities...
Wed Aug 19, 2020 13:07
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου