Gonorrhea is the second most common sexually transmitted bacterial infection (STI) next to Chlamydia. Untreated cases could results in major complications like pelvic inflammatory disease (PID), ectopic pregna...
Tue Aug 18, 2020 03:00
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Phyu Phyu Khin, Seon-Heui Cha, Hee-Sook Jun, Jong Han Lee
Wed Aug 19, 2020 17:34
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Hanjun Lee
Wed Aug 19, 2020 17:34
Background: Numerous studies have reported positive effects of exercise training in patients with interstitial lung disease (ILD) on physical capacity and quality of life. However, evidence is rare on the effects of specific forms of training and further pathophysiological mechanisms in these patients. Objectives: In this multicenter study we aimed to explore the clinical effects of whole-body vibration training (WBVT) in patients with ILD on various outcome measures, including proinflammatory cytokines...
Wed Aug 19, 2020 15:05
Between-week reliability of the cervical range of motion (CROM) device for upper cervical rotation. J Man Manip Ther. 2020 Aug 18;:1-5 Authors: Gugliotti M, Tau J, Gallo K, Sagliocca N, Horan M, Sussman N, Wisnewski R Abstract BACKGROUND: The Cervical Range of Motion (CROM) device is a valid and reliable clinical tool used to measure full cervical rotation, however, its reliability for measuring upper cervical rotation is unknown. ...
Wed Aug 19, 2020 16:44
Related Articles Selective stimulation of human intrinsic laryngeal muscles: Analysis in a mathematical three-dimensional space. Laryngoscope. 2020 04;130(4):967-973 Authors: Broniatowski M, Grundfest-Broniatowski S, Schiefer M, Ludlow DH, Broniatowski DA, Tucker HM Abstract OBJECTIVES/HYPOTHESIS: Standard stimulating methods using square waves do not appropriately restore physiological control of individual intrinsic laryngeal muscles (ILMs)....
Wed Aug 19, 2020 16:44
Publication date: Available online 18 August 2020Source: CortexAuthor(s): Jennifer Wagner, Silvia Lo Monaco, Federica Contò, Danielle Parrott, Lorella Battelli, Elena Rusconi
Wed Aug 19, 2020 15:37
Antiviral Chemistry and Chemotherapy, Volume 28, Issue , January-December 2020. Tick-borne encephalitis is an important human arbovirus neuroinfection spread across the Northern Eurasia. Inhibitors of tick-borne encephalitis virus (TBEV) strain Absettarov, presumably targeting E protein n-octyl-β-d-glucoside (β-OG) pocket, were reported earlier. In this work, these inhibitors were tested in vitro against seven strains representing three main TBEV subtypes. The most potent compound, 2-[(2-methyl-1-oxido-5,6,7,8-tetrahydroquinazolin-4-yl)amino]-phenol,...
Wed Aug 19, 2020 07:51
A 76-year-old male presented with a small hyperreflective density in the outer nuclear layer with subtle retinal pigment epithelium (RPE) elevation and few intraretinal cysts on spectral-domain optical coherence tomography (SD-OCT). Optical coherence tomography angiography (OCTA) confirmed the presence of a tuft-shaped intraretinal neovascular lesion. SD-OCT performed 2 months before showed a smaller RPE elevation at the same location without intraretinal fluid. A 79-year-old male presented with...
Wed Aug 19, 2020 15:09
Abstract The aim of the present work was the biophysical characterization of the Amynthas gracilis hemoglobin (HbAg). The oxy-HbAg optical absorption data, with Soret and Q bands centered at 415, 540 and 575 nm, were stable and unchanged at pH 7.0. An increase in pH promotes decrease in the intensity in the optical absorption bands, suggesting an oligomeric dissociation and partial oxidation. Identical stability at pH 7.0 was observed in DLS results that presented a hydrodynamic...
Wed Aug 19, 2020 03:00
Publication date: Available online 19 August 2020Source: TalantaAuthor(s): Jun Xie, Qiannan Pan, Feili Li, Yuyi Tang, Shiwei Hou, Changhua Xu
Wed Aug 19, 2020 14:42
Publication date: Available online 18 August 2020Source: TalantaAuthor(s): Ademar Wong, Anderson Martin Santos, Rafael da Fonseca Alves, Fernando Campanhã Vicentini, Orlando Fatibello-Filho, Maria Del Pilar Taboada Sotomayor
Wed Aug 19, 2020 14:42
Tue Aug 18, 2020 12:14
Abstract There is a lack of real practice studies comparing ustekinumab and ixekizumab effectiveness and safety. The main aim of this study was to compare the effectiveness and safety of both drugs used to treat moderate‐to‐severe psoriasis patients over 52 weeks. The secondary objective was to identify which clinical variables could have an impact on its effectiveness. A retrospective observational study was carried out, comparing the first 28 patients treated with ustekinumab after its commercialization...
Tue Aug 18, 2020 12:12
Abstract Background Although low child and adult grip strength is associated with adverse cardiometabolic health, how grip strength across the life course associates with type 2 diabetes is unknown. This study identified the relative contribution of grip strength measured at specific life stages (childhood, young adulthood, mid-adulthood) with prediabetes or type 2 diabetes in mid-adulthood. ...
Wed Aug 19, 2020 03:00
Abstract Autoregulation is a process that is used to manipulate training based primarily on the measurement of an individual’s performance or their perceived capability to perform. Despite being established as a training framework since the 1940s, there has been limited systematic research investigating its broad utility. Instead, researchers have focused on disparate practices that can be considered specific examples of the broader autoregulation training framework. A primary...
Wed Aug 19, 2020 03:00
Changes caused by chronic Toxoplasma gondii infection in the colonic myenteric plexus of rats. Chronic T. gondii infection causes loss of nitrergic and cholinergic neurons and hypertrophy of nitrergic neurons in the proximal colon. Reduced number of cholinergic neurons and morphological alterations in general myenteric neurons was observed in the distal colon. Myenteric structural alterations resulted in slower migration of the colonic motor complex (CMMC). Abstract Background Toxoplasma...
Tue Aug 18, 2020 20:24
Using an original methodology to study the responses to gas infusion into the stomach in patients with functional gastrointestinal disorders, we found that different pathophysiological mechanisms underlay specific adaptive responses to gastric gas in patients with different functional gut disorders. Abstract Background Gas‐related abdominal symptoms are common in patients with functional gut disorders, but the responses to cope with the large volumes of gas that enter daily into the stomach...
Tue Aug 18, 2020 12:30
Abstract Lichen planus is a very common autoimmune inflammatory disease, affecting 1‐3% of general population Its oral form ‐ also known as Oral Lichen Planus ‐ is the most common, with a prevalence between 1% and 2% in the general population. LP lesions were discovered in the esophagus in OLP patients. The malignant transformation risk of those lesions is currently unknown, but it can be equivalent to oral lesions ‐ approximately 1‐3%. Our study points towards the presence of pharyngolaryngeal...
Tue Aug 18, 2020 13:34
Abstract Background The Norwegian Ministry of Health and Care Services initiated a project including experimental treatment for patients with health complaints attributed to amalgam restorations. Objective The aim was to evaluate changes of general health complaints in patients who participated in the project and had all amalgam restorations removed. Methods The project was designed as a prospective cohort study and organized by the Dental Biomaterials Adverse Reaction Unit in Bergen,...
Tue Aug 18, 2020 22:00
Abstract Background Tongue motor biomechanics during swallowing was not fully elucidated due to the technical difficulty. Objective To evaluate the relationship between tongue motion and tongue pressure production by simultaneously measuring tongue motion and tongue pressure during water swallowing. Methods In 12 healthy male participants (mean age, 30.8±4.2 years), tongue pressure and tongue motion trajectory during dipper and tipper type swallows of 3 ml of water were measured using...
Tue Aug 18, 2020 13:34
Abstract Cardiac death is the second most prevalent cause in Prader‐Willi syndrome (PWS). Paediatric patients with PWS often present cardiac autonomic dysfunction during wakefulness, obesity and sleep‐disordered breathing. However, the extent of cardiac autonomic modulation during sleep in PWS has not been documented. The objective of this study was to assess alterations in cardiac autonomic modulation of paediatric patients with PWS during different sleep stages. Thirty‐nine participants in three...
Tue Aug 18, 2020 16:58
Summary Insomnia predicts the onset of depression, commonly co‐presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently using depression‐specific therapies. Cognitive behavioural therapy for insomnia may be an appropriate treatment to improve both insomnia and depressive symptoms. We examined the effects of a fully‐automated digital cognitive behavioural therapy intervention for insomnia (Sleepio) on insomnia and...
Tue Aug 18, 2020 14:01
Abstract Context Patients with adrenal insufficiency (AI) have excess mortality and morbidity, mainly due to cardiovascular (CV) diseases. The mechanisms for this is unclear. Objective To assess CV structure and function in AI patients on conventional replacement therapy and after switching to once-daily, modified-release hydrocortisone (OD-HC) in...
Wed Aug 19, 2020 03:00
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Lipomas are the most common benign soft tissue tumor. Yet, strikingly simple tumors can become problematic when compounded by odd characteristics such as size and location. We report the case of a 53-year-old male who developed complete right lung collapse secondary to a large right-sided chest wall lipoma with accelerated growth in the past 6 months. Bronchoscopy revealed extrinsic compression of...
Tue Aug 18, 2020 10:15
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. A 35-year-old male presented to our university hospital with night sweats, fevers, ulcerated skin lesions to the lower mouth and posterior neck, shortness of breath, and an enlarging cervical lymph node. The patient was evaluated 2 months prior for respiratory symptoms, cervical lymphadenopathy, and skin lesions resulting in a diagnosis of primary pulmonary coccidioidomycosis and was treated with...
Tue Aug 18, 2020 10:15
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