Mesenchymal stem cells (MSCs) are multipotent cells that demonstrate therapeutic potential for the treatment of acute and chronic inflammatory-mediated conditions. Especially for acute conditions, it is critic...
Wed Aug 19, 2020 03:00
Abstract Rationale Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains unclear whether intravenous (i.v.) administration would facilitate the rapid elevation of dopamine levels associated with stimulant drugs. ...
Wed Aug 19, 2020 03:00
As a child, you probably played the game "Telephone": you whispered a message into the ear of the person next to you, who whispered it to the next person, and so forth down the line. When revealed at the end of the chain, the message was inevitably garbled, illustrating how fragile human…
Wed Aug 19, 2020 03:00
During the coronavirus pandemic, the U.S. unemployment rate reached 14.7%, the highest level since the Great Depression. More than 40 million people filed for unemployment insurance between March and May 2020, and official statistics may understate the true extent of job disruptions. Widespread…
Wed Aug 19, 2020 03:00
Cold atmospheric plasma (CAP), which is ionized gas produced at atmospheric pressure, could be a novel and potent antimicrobial therapy for the treatment of infected wounds. Previously we have shown that CAP g...
Wed Aug 19, 2020 03:00
Background: The World Health Organisation declared a coronavirus disease 2019 (COVID-19) pandemic on March 11, 2020. Following activation of the UK pandemic response, our institution began planning for admission of COVID-19 patients to the neurointensive care unit (neuro-ICU) to support the local critical care network which risked being rapidly overwhelmed by the high number of cases. This report will detail our experience of repurposing a neuro-ICU for the management of severely ill patients...
Tue Aug 18, 2020 03:00
The Caribbean offers a unique opportunity to study evolutionary dynamics in insular mammals. However, the recent extinction of most Caribbean non-volant mammals has obstructed evolutionary studies, and poor DN...
Tue Aug 18, 2020 03:00
Pseudogamy is a reproductive system in which females rely on the sperm of males to activate their oocytes, generally parasitizing males of other species, but do not use the sperm DNA. The nematode Mesorhabditis b...
Tue Aug 18, 2020 03:00
Microbiomes can have profound impacts on host biology and evolution, but to date, remain vastly understudied in spiders despite their unique and diverse predatory adaptations. This study evaluates closely rela...
Tue Aug 18, 2020 03:00
Abstract Objectives A life-course perspective emphasizes healthy behaviors before, during, and after pregnancy to support a multi-generational risk reduction in obesity for mothers and infants. Optimal timing, content, and dose of such interventions is not well defined. Methods We conducted a nested cohort within a randomized trial to evaluate whether...
Wed Aug 19, 2020 03:00
Abstract Objective To analyze municipal- and individual-level factors related to the prevalence of teenage pregnancy in Colombia during 2015. Methods We analyzed 660,767 births registers, of which 21.5% recorded adolescent women. At an individual level, marital status, educational level, area of residence, and access to health services were included...
Wed Aug 19, 2020 03:00
Oncogenesis, Published online: 19 August 2020; doi:10.1038/s41389-020-00256-0Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition
Wed Aug 19, 2020 03:00
Sepsis is a syndrome involving life-threatening organ dysfunction. The present study aimed to determine whether septic AKI, ARDS, DIC, and shock can be predicted more readily by combining uNGAL values and infl...
Tue Aug 18, 2020 03:00
Mucosal Immunology, Published online: 19 August 2020; doi:10.1038/s41385-020-00336-9A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
Wed Aug 19, 2020 03:00
Publication date: Available online 19 August 2020Source: Sleep MedicineAuthor(s): Ilona Merikanto, Timo Partonen
Wed Aug 19, 2020 21:39
Publication date: Available online 19 August 2020Source: Sleep MedicineAuthor(s): Frances Chung
Wed Aug 19, 2020 21:39
Publication date: Available online 18 August 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christian-Alexander Behrendt, Oliver Lyons
Wed Aug 19, 2020 20:03
Publication date: Available online 18 August 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Aminder A. Singh, Jonathan R. Boyle
Wed Aug 19, 2020 20:03
Publication date: Available online 18 August 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Rolla Zarifa, Ross Milner
Wed Aug 19, 2020 20:03
This article describes a method for culturing and analyzing glomerular parietal epithelial cell outgrowths of encapsulated glomeruli isolated from mouse kidney. This method can be used to study pathways involved in parietal epithelial cell proliferation and migration.
Wed Aug 19, 2020 20:00
Organisms need to work together to adapt to climate change, especially in the presence of competitors, suggests a new study.
Tue Aug 18, 2020 18:49
A new study shows how differentiation of a single gene changes behavior in a wild songbird, determining whether the white-throated sparrow displays more, or less, aggression.
Tue Aug 18, 2020 18:49
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου