Bilirubin-induced hyperexcitation in developing auditory neurons
The role of gamma-aminobutyric acid/glycinergic synaptic transmission in mediating bilirubin-induced hyperexcitation in developing auditory neurons via ScienceDirect Publication: Toxicology Letters Publication date: 5 January 2016 *Source:*Toxicology Letters, Volume 240, Issue 1 Author(s): Xin-Lu Yin, Min Liang, Hai-Bo Shi, Lu-Yang Wang, Chun-Yan Li, Shan-Kai Yin Hyperbilirubinemia is a common clinical phenomenon observed in human newborns. A high level of bilirubin can result in severe jaundice and bilirubin encephalopathy. However, the cellular mechanisms underlying bilirubin excitot...περισσότερα »
Contrast agent induced nephropathy
A novel protective formulation of Palmitoylethanolamide in experimental model of via ScienceDirect Publication: Toxicology Letters Publication date: 5 January 2016 *Source:*Toxicology Letters, Volume 240, Issue 1 Author(s): M. Cordaro, D. Impellizzeri, G. Bruschetta, R. Siracusa, R. Crupi, R. Di Paola, E. Esposito, S. Cuzzocrea Contrast-induced nephropathy (CIN) is a complication in patients after administration of iodinated contrast media. Several risk factors contribute to the development and progression of CIN, including hypertension, diabetes, and dyslipidemia. Animal models of CI... περισσότερα »
Streptobacillus moniliformis bacteremia in a rheumatoid arthritis patient without a rat bite: a case report
Streptobacillus moniliformis bacteremia in a rheumatoid arthritis patient without a rat bite: a case report: Background: Rat bite fever is a relatively rare infectious disease due to infection with Streptobacillus moniliformis or Spirillum minus mainly via directs bite by rats, mice, or other rodents. If there is no clear bite history, the diagnosis is difficult or may not be made.Case presentationA 72-year-old Asian female with rheumatoid arthritis was admitted for high grade fever and walking difficulty with severe lumbago. Initially, we suspected lumber compression fracture with d... περισσότερα »
Value of the prognostic nutritional index and weight loss in predicting metastasis and long-term mortality in nasopharyngeal carcinoma
Value of the prognostic nutritional index and weight loss in predicting metastasis and long-term mortality in nasopharyngeal carcinoma: Background: To evaluate the influence of the progonistic nutritional index (PNI) and weight loss on metastasis and long-term mortality in nasopharyngeal carcinoma (NPC). Methods: We retrospectively reviewed 694 newly diagnosed patients with non-disseminated, biopsy-proven NPC. Survival analysis was used to evaluate the predictive value of PNI and weight loss. Results: Multivariate analysis demonstrated that a low pre-therapy PNI (< 55.0) was an indepe...περισσότερα »
Evaluation of the effect of tooth and dental restoration material on electron dose distribution and production of photon contamination in electron beam radiotherapy
Evaluation of the effect of tooth and dental restoration material on electron dose distribution and production of photon contamination in electron beam radiotherapy: AbstractThe aim of this study is to evaluate the effect of tooth and dental restoration materials on electron dose distribution and photon contamination production in electron beams of a medical linac. This evaluation was performed on 8, 12 and 14 MeV electron beams of a Siemens Primus linac. MCNPX Monte Carlo code was utilized and a 10 × 10 cm2 applicator was simulated in the cases of tooth and combinations of tooth ...περισσότερα »
Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations
Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations: An emergent concept in neurosciences consists in considering brain functions as the product of dynamic interactions between neurons and glial cells, particularly astrocytes. Although the role played by astrocytes in synaptic transmission and plasticity is now largely documented, their contribution to neuronal network activity is only beginning to be appreciated. In mouse olfactory bulb slices, we observed that the membrane potential of mitral cells oscillates between UP and DOWN states at a low frequenc... περισσότερα »
Mindfulness Meditation-Based Pain Relief Employs Different Neural Mechanisms Than Placebo and Sham Mindfulness Meditation-Induced Analgesia
Mindfulness Meditation-Based Pain Relief Employs Different Neural Mechanisms Than Placebo and Sham Mindfulness Meditation-Induced Analgesia: Mindfulness meditation reduces pain in experimental and clinical settings. However, it remains unknown whether mindfulness meditation engages pain-relieving mechanisms other than those associated with the placebo effect (e.g., conditioning, psychosocial context, beliefs). To determine whether the analgesic mechanisms of mindfulness meditation are different from placebo, we randomly assigned 75 healthy, human volunteers to 4 d of the following:... περισσότερα »
Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus
Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus: Circuit dysfunction in complex brain disorders such as schizophrenia and autism is caused by imbalances between inhibitory and excitatory synaptic transmission (I/E). Short-term plasticity differentially alters responses from excitatory and inhibitory synapses, causing the I/E ratio to change as a function of frequency. However, little is known about I/E ratio dynamics in complex brain disorders. Transcriptional dysregulation in interneurons, ... περισσότερα »
Layer-Specific fMRI Responses to Excitatory and Inhibitory Neuronal Activities in the Olfactory Bulb
Layer-Specific fMRI Responses to Excitatory and Inhibitory Neuronal Activities in the Olfactory Bulb: High-resolution functional magnetic resonance imaging (fMRI) detects localized neuronal activity via the hemodynamic response, but it is unclear whether it accurately identifies neuronal activity specific to individual layers. To address this issue, we preferentially evoked neuronal activity in superficial, middle, and deep layers of the rat olfactory bulb: the glomerular layer by odor (5% amyl acetate), the external plexiform layer by electrical stimulation of the lateral olfactor... περισσότερα »
Head-Directional Tuning and Theta Modulation of Anatomically Identified Neurons in the Presubiculum
Head-Directional Tuning and Theta Modulation of Anatomically Identified Neurons in the Presubiculum: The presubiculum provides a major input to the medial entorhinal cortex (MEC) and contains cells that encode for the animal's head direction (HD), as well as other cells likely to be important for navigation and memory, including grid cells. To understand the mechanisms underlying HD cell firing and its effects on other parts of the circuit, it is important to determine the anatomical identity of these functionally defined cells. Therefore, we juxtacellularly recorded single cells i... περισσότερα »
Continuous Noninvasive Arterial Blood Pressure Readings : The CNAP®Device Compared with Invasive Radial Artery Measurements
The Accuracy of the CNAP®Device Compared with Invasive Radial Artery Measurements for Providing Continuous Noninvasive Arterial Blood Pressure Readings at a Medical Intensive Care Unit: A Method-Comparison Study: [image: image] BACKGROUND: In cases of intensive care unit (ICU) patients without an arterial line, noninvasive continuous blood pressure monitoring could be very beneficial. The CNAP® monitor (CNSystems Medizintechnik AG) provides noninvasive, beat-to-beat blood pressure (BP) estimates using the volume clamp method to measure finger arterial pressure calibrated to brachial... περισσότερα »
The Effect of Systemic Magnesium on Postsurgical Pain in Children Undergoing Tonsillectomies
The Effect of Systemic Magnesium on Postsurgical Pain in Children Undergoing Tonsillectomies: A Double-Blinded, Randomized, Placebo-Controlled Trial: BACKGROUND: Tonsillectomy is a frequently performed surgical procedure in children; however, few multimodal analgesic strategies have been shown to improve postsurgical pain in this patient population. Systemic magnesium infusions have been shown to reliably improve postoperative pain in adults, but their effects in pediatric surgical patients remain to be determined. In the current investigation, our main objective was to evaluate the... περισσότερα »
Caring for the Jehovah's Witness Parturient
Caring for the Jehovah's Witness Parturient: [image: image] Caring for the Jehovah's Witness parturient is a complex task that presents a number of ethical, medical, and legal concerns because many Jehovah's Witnesses refuse allogeneic blood transfusion. Childbirth and its surrounding events may be associated with significant blood loss. Given their significant role in the intraoperative administration of blood products, anesthesia providers should be familiar with factors that must be considered in the perioperative care of Jehovah's Witness parturients. Several pharmacologic ther... περισσότερα »
JAMA Facial Plastic Surgery
November-December 2015 Issue Highlights Considerations for Achieving a Natural Face in Cosmetic Procedures This Viewpoint questions the definition of natural beauty and asserts that if plastic surgeons would examine kinetic models instead of static images, the outcomes of popular procedures would be closer to natural beauty ideal. Thank You on Behalf of JAMA Facial Plastic Surgery During the course of this inaugural year as the new editor of JAMA Facial Plastic Surgery, I have shared my vision for the journal, introduced new article categories, and discussed the importance of striv...περισσότερα »
Obliquity of the stapes in otosclerosis
Main ArticleObliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgeryV Ananda1 c1 and H N Udayabhanua1 a1 Department of Otorhinolaryngology and Head and Neck Surgery, MCV Memorial ENT Trust Hospital, Pollachi, Tamil Nadu, India Abstract Objective: To establish the prevalence of stapes obliquity as observed in otosclerosis patients during stapes surgery by a simple method of intra-operative measurement. Design: Prospective observational study. Results: Intra-operative measurements showed that the mean distance (± standard deviation) betwee... περισσότερα »
Tinnitus-related handicap
Main ArticleThe impact of tinnitus characteristics and associated variables on tinnitus-related handicapS Degeesta1 c1, P Corthalsa1a3, I Dhoogea2 and H Kepplera1 a1 Department of Speech, Language and Hearing Sciences, Ghent University, Belgium a2 Department of Otorhinolaryngology, Ghent University, Belgium a3 Faculty of Education, Health and Social Work, University College Ghent, Belgium Abstract Objective: This study aimed to determine the characteristics of tinnitus and tinnitus-related variables and explore their possible relationship with tinnitus-related handicap. Methods: Eight...περισσότερα »
Topical quinolones do not carry the same risk of ototoxicity as aminoglycosides. Furthermore, they are equal or more effective in treating chronic suppurative otitis media and when used as prophylaxis post-myringotomy. Topical quinolones should be considered a first-line treatment for these patients.
Review ArticleWhy are ototopical aminoglycosides still first-line therapy for chronic suppurative otitis media? A systematic review and discussion of aminoglycosides versus quinolonesA S Harrisa1 c1, H A Elhassana2 and E P Flooka1 a1 Department of Otorhinolaryngology, Betsi Cadwaladr University Health Board, Rhyl, Wales, UK a2 Department of Otorhinolaryngology, Cardiff and Vale University Health Board, Cardiff, Wales, UK Abstract Objective: This systematic review aimed to establish that quinolones are as effective as aminoglycosides when used to treat chronic suppurative otitis media... περισσότερα »
The Journal of Laryngology Otology
*FirstView Article(s)The Journal of Laryngology Otology, FirstView Article(s) The Journal of Laryngology Otology ( JLO ) is a leading monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialities. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area, regardless of the country in which they practise. JLO contains main articles (original, review and historical), ca... περισσότερα »
Intraoperative Free Flap Monitoring Using Indocyanine Green
Intraoperative Free Flap Monitoring Using Indocyanine Green: As experience and widespread use of free tissue transfer has increased for head and neck reconstruction over the past 20 years, success rates have generally stabilized at well over 95% in most experienced surgeons' hands. Free tissue transfer has clearly been shown to be the standard of care in complex oromandibular reconstruction. However, it represents substantial use of financial and surgeon resources. Failure, although infrequent, is costly from all perspectives. As such, most microvascular surgeons have used various m... περισσότερα »
Considerations for Achieving a Natural Face in Cosmetic Procedures
Considerations for Achieving a Natural Face in Cosmetic Procedures: This Viewpoint questions the definition of natural beauty and asserts that if plastic surgeons would examine kinetic models instead of static images, the outcomes of popular procedures would be closer to natural beauty ideal. [image: First page PDF preview]
Transcutaneous Skin-Muscle Flap Suspension Lower-Eyelid Blepharoplasty
Transcutaneous Skin-Muscle Flap Suspension Lower-Eyelid Blepharoplasty: This Surgical Pearl with video details the procedure for transcutaneous lower-eyelid blepharoplasty with skin-muscle flap suspension for lower eyelid rejuvenation. [image: First page PDF preview]
Delayed Complications After Cochlear Implantation
Delayed Complications After Cochlear Implantation: This systematic review describes the reported rates and types of delayed complications after cochlear implantation in adults and children. *Importance* Surgeons should understand the potential long-term complications in patients who undergo cochlear implantation (CI) and should be able to facilitate counseling. *Objectives* To review the delayed complications after CI and some of the management plans used to treat these complications. *Evidence Acquisition* The PubMed and OVID databases were searched for articles published from...περισσότερα »
Middle Ear Response of Mucins to Nontypeable Haemophilus influenzae
Middle Ear Response of Mucins to Nontypeable Haemophilus influenzae: This in vitro study evaluates the secretion of airway mucin glycoproteins characteristic of chronic otitis media with effusion after exposure to nontypeable Haemophilus influenzae lysates. *Importance* Chronic otitis media with effusion is characterized by middle ear secretion of mucin glycoproteins, predominantly MUC5B; MUC5AC, the other secretory mucin studied frequently, has also been identified in the middle ear. Emerging evidence suggests a dichotomous role for these mucins in innate immune responses. We h...περισσότερα »
Assessment of Blinding in a Tinnitus Treatment Trial
Assessment of Blinding in a Tinnitus Treatment Trial: *In Reply* As we stated in Supplement 2 of our recent article, "Blinding has presented a substantial methodological challenge in previous rTMS studies, primarily because clinicians delivering treatment usually knew when active or placebo stimulation was being administered. In most studies, it was also easy for research subjects to distinguish between active and placebo rTMS conditions." For this reason, we used a parallel study design, instead of a crossover design, for our clinical trial. Indeed, adequate blinding remains proble... περισσότερα »
Influence of Ossicular Chain Damage on Postoperative Hearing
Influence of Ossicular Chain Damage on Postoperative Hearing: This systematic review and meta-analysis investigated the influence of preoperative ossicular chain damage on hearing outcomes in patients after chronic otitis media and/or cholesteatoma surgery. *Importance* Physicians should ideally be able to provide patients with chronic otitis media and/or cholesteatoma specific information about postoperative hearing outcome, based on their level of preoperative ossicular chain damage (OCD). *Objective* To identify the influence of preoperative OCD on hearing outcomes in patien... περισσότερα »
Dental Trauma and Oral Cavity Cancer
Dental Trauma and Oral Cavity Cancer: *In Reply* The focus of much current research has been the role of human papilloma virus (HPV) in oropharyngeal cancer, especially as a separate risk factor, or even disease process, compared with smoking-related cancer of the oropharynx. Our data support previous research showing that oral cavity cancer is slightly more prevalent than oropharyngeal cancer, and that this disparity is largely due to increased numbers of nonsmokers, especially women, who develop oral cavity cancers. In our series, oral cavity cancers occurred in lifelong nonsmoker... περισσότερα »
Effect of Continued Therapy on Productivity Costs for Refractory Rhinosinusitis
Effect of Continued Therapy on Productivity Costs for Refractory Rhinosinusitis: This observational study estimates the effects of medical therapy for chronic rhinosinusitis on factors associated with productivity and costs. *Importance* It is estimated that lost productivity related to chronic rhinosinusitis (CRS) costs society in excess of $13 billion per year in the United States. Given this tremendous cost to society, it is important to evaluate the effect of current interventions on improving this productivity loss. *Objective* To define the change in productivity costs in... περισσότερα »
Antibiotika-Anwendung 2012/13 in 109 deutschen Akutkrankenhäusern
Antibiotika-Anwendung 2012/13 in 109 deutschen Akutkrankenhäusern: Dtsch med Wochenschr 2015; 140: e237-e246 DOI: 10.1055/s-0041-105938 Hintergrund | Mit der zunehmenden bakteriellen Resistenz-Entwicklung und dem Anstieg der Clostridium-difficile-Infektionen wird die Sicherstellung einer rationalen und intelligenten Antibiotikaverordnung immer wichtiger. Voraussetzung hierfür sind auch zuverlässige Daten zur Antibiotikaverschreibung. Bisher waren solche Daten für Akutkrankenhäuser in Deutschland nicht ausreichend verfügbar. Methode | Wir analysierten die Antibiotikaverordnungsmengen aus ... περισσότερα »
Risk Estimation for Complications After Oral Cavity Cancer
Risk Estimation for Complications After Oral Cavity Cancer: The authors of this retrospective case series describe their development and validation of a statistical tool to predict an individual patient's risk of developing a major complication after surgery for oral cavity cancer. Postoperative complications after head and neck surgery carry the potential for significant morbidity. Estimating the risk of complications in an individual patient is challenging. *Objective* To develop a statistical tool capable of predicting an individual patient's risk of developing a major complic... περισσότερα »
Laryngeal Electromyography Guidelines for Injection Augmentation
Laryngeal Electromyography Guidelines for Injection Augmentation *In Reply* I would like to thank Tang and coauthors1 for their comments on our recent article2 and for giving me the opportunity to further clarify our technique. First, they1 express doubt about the usefulness of laryngeal electromyography (LEMG) guidance in a paralyzed vocal fold with absolutely no electrical activity. Actually, this condition rarely occurs because of the strong likelihood of laryngeal reinnervation after recurrent laryngeal nerve injury.3In an online video published with our article, we show a su... περισσότερα »
Chronic Aspiration in Children With Normal Upper Airway Anatomy
Chronic Aspiration in Children With Normal Upper Airway Anatomy: This case series characterizes clinical characteristics and outcomes of children with chronic aspiration and normal upper airway anatomy treated at a single academic referral center. *Importance* Chronic airway aspiration is a challenging problem for physicians and caregivers and can cause significant pulmonary morbidity in pediatric patients. Our knowledge regarding the causes and optimal management of these patients is in its infancy. *Objective* To review our experience with the evaluation and management of ped... περισσότερα »
Development of cell-cycle checkpoint therapy for solid tumors
Development of cell-cycle checkpoint therapy for solid tumors: Cellular proliferation is tightly controlled by several cell-cycle checkpoint proteins. In cancer, the genes encoding these proteins are often disrupted and cause unrestrained cancer growth. The proteins are over-expressed in many malignancies; thus, they are potential targets for anti-cancer therapies. These proteins include cyclin-dependent kinase, checkpoint kinase, WEE1 kinase, aurora kinase and polo-like kinase. Cyclin-dependent kinase inhibitors are the most advanced cell-cycle checkpoint therapeutics available. F... περισσότερα »
Safety and efficacy of concurrent carboplatin plus radiotherapy for locally advanced head and neck cancer patients ineligible for treatment with cisplatin
Safety and efficacy of concurrent carboplatin plus radiotherapy for locally advanced head and neck cancer patients ineligible for treatment with cisplatin: Objective Cisplatin-based chemoradiotherapy is the standard treatment for patients with locally advanced squamous cell carcinoma of the head and neck. However, patients with advanced age, renal, cardiac or neurogenic dysfunction seem ineligible for cisplatin treatment. We evaluated the safety and efficacy of concurrent carboplatin plus radiotherapy in patients ineligible for cisplatin usage. Methods We retrospectively analyzed ... περισσότερα »
External Auditory Canal Osteoma A Case Report
Rachana Dhakal Ramesh Makaju and Ashish Dhakal from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1HcaAwR via IFTTT
Randomized, prospective assessment of moisturizer efficacy for the treatment of radiation dermatitis following radiotherapy
Randomized, prospective assessment of moisturizer efficacy for the treatment of radiation dermatitis following radiotherapy after breast-conserving surgery: Objective The effect of heparinoid moisturizer use after acute skin damage for patients receiving whole-breast radiotherapy after lumpectomy is understudied. Methods A total of 30 patients were randomly assigned to receive heparinoid moisturizer (Group M), and 32 patients comprised the control group (Group C). Patients in Group M were instructed to apply heparinoid moisturizer from 2 weeks following whole-breast radiotherapy, ... περισσότερα »
Penicillin skin testing is a safe method to guide β-lactam administration in the intensive care unit
Penicillin skin testing is a safe method to guide β-lactam administration in the intensive care unit: Geng et al1 analyzed factors associated with negative histamine control reactions in patients evaluated with a penicillin skin test (PST) for allergy to β-lactams. In a case–control study of 52 patients with a negative response and 125 controls with a normal response, they used histamine dihydrochloride at a concentration of 6 mg/mL for prick or puncture skin testing but did not perform intradermal testing.1 Admission to an intensive care unit (ICU), older age, and treatment with sy... περισσότερα »
Antibiotic susceptibility of Acinetobacter species in intensive care unit
Antibiotic susceptibility of Acinetobacter species in intensive care unit in Montenegro.: Authors: Mijovic G, Pejakov L, Vujosevic D Abstract The global increase in multidrug resistance of Acinetobacter has created widespread problems in the treatment of patients in intensive care units (ICUs). The aim of this study was to assess the current level of antimicrobial susceptibility of Acinetobacter species in ICU of Clinical Centre of Montenegro and determine their epidemiology. Antibiotic susceptibility was tested in 70 isolates of Acinetobacter collected from non-repeating samples tak... περισσότερα »
Invasive fungal infection in neonatal intensive care units
Invasive fungal infection in neonatal intensive care units: a multicenter survey.: This study assesses the epidemiology of invasive fungal infection (IFI) in Portuguese Neonatal Intensive Care Units (NICUs) and compares the effectiveness and safety of antifungal therapies. A survey concerning the period 2005-2010 was carried out in NICUs of Greater Lisbon. Among 10 473 admitted neonates, 44 cases were identified, 29 among extreme low birth weight neonates (65·9%). Cumulative incidence rate was 0·42% (95%CI 0·309-0·559). A central venous catheter was present before IFI in all cases. ...περισσότερα »
Carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii isolates
Determination of synergy between sulbactam, meropenem and colistin in carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii isolates and correlation with the molecular mechanism of resistance.: Authors: Laishram S, Anandan S, Devi BY, Elakkiya M, Priyanka B, Bhuvaneshwari T, Peter JV, Subramani K, Balaji V Abstract Treatment of infections with carbapenem-resistant Gram negative organism is a major challenge especially among intensive care patients. Combinations of sulbactam, meropenem and colistin was studied for its synergistic activity against 100 invasive isolates... περισσότερα »
Severe Anaphylactic Reaction Secondary to Isosulfan Blue Dye Injection
A Case of Severe Anaphylactic Reaction Secondary to Isosulfan Blue Dye Injection.: CONCLUSION: Sentinel lymph node biopsy is the standard of care for staging several cancers, and isosulfan blue is the dye most commonly used for this procedure. Reactions to the dye occur in some patients; however, we recommend the continued use of isosulfan blue dye for lymph node mapping given the low incidence of adverse effects, with no reported mortalities. Physicians should be prepared for the potential risk of anaphylactic shock. PMID: 26130983 [PubMed] (Source: Ochsner Journal)
Morphine infusions after pediatric cranial surgery
Morphine infusions after pediatric cranial surgery: a retrospective analysis of safety and efficacy.: CONCLUSIONS: These findings suggest that CMI is as safe a treatment option as acetaminophen and codeine. Careful observation enables nurses to safely administer a CMI for children following cranial surgery on a surgical unit setting. PMID: 18856095 [PubMed - indexed for MEDLINE] (Source: Canadian Journal of Neuroscience Nursing)
Comparison of gastric and other bowel perforations in preterm infants
Comparison of gastric and other bowel perforations in preterm infants: a review of 20 years' experience in a single institution.: CONCLUSION: Patients with gastric perforation did not have a common clinical finding preceding the perforation diagnosis. Although mortality in previous studies was high, all patients survived to discharge in the present study. When a preterm infant aged less than one week presents with sudden abdominal distension and pneumoperitoneum, gastric perforation should first be excluded. Prompt exploratory laparotomy will increase the survival rates of these inf...περισσότερα »
Croup and epiglottitis
Clinical characteristics of children and adolescents with croup and epiglottitis who visited 146 Emergency Departments in Korea.: CONCLUSION: Both groups had similar sex ratios, arrival times, 3 most common chief complaints, and 5 most common comorbidities. Epiglottitis patients had a lower incidence rate, higher mean age of onset, and higher hospitalization rate and experienced dyspnea, sore throat, and vomiting more often than croup patients. Our results may help in the differential diagnosis of croup and epiglottitis. PMID: 26576182 [PubMed - as supplied by publisher] (Source: Kor...περισσότερα »
Ultrasound-guided internal jugular vein catheterization in critically ill pediatric patients.
Ultrasound-guided internal jugular vein catheterization in critically ill pediatric patients.: CONCLUSION: The results suggest that ultrasound-guided IJV catheterization can be performed easily and without any serious complications in pediatric patients, even when performed by visiting house staff. Therefore, ultrasound-guided IJV catheterization is strongly recommended for critically ill pediatric patients. PMID: 25932035 [PubMed] (Source: Korean Journal of Pediatrics)
Correlation between theoretical anatomical patterns of lymphatic drainage and lymphoscintigraphy findings during sentinel node detection in head and neck melanomas
Correlation between theoretical anatomical patterns of lymphatic drainage and lymphoscintigraphy findings during sentinel node detection in head and neck melanomas: Abstract PurposeIn the diagnosis of head and neck melanoma, lymphatic drainage is complex and highly variable. As regional lymph node metastasis is one of the most important prognostic factors, lymphoscintigraphy can help map individual drainage patterns. The aim of this study was to compare the results of lymphoscintigraphy and sentinel lymph node (SLN) detection with theoretical anatomical patterns of lymphatic drain...περισσότερα »
Human Frequency Following Response: Neural Representation of Envelope and Temporal Fine Structure in Listeners with Normal Hearing and Sensorineural Hearing Loss.
Human Frequency Following Response: Neural Representation of Envelope and Temporal Fine Structure in Listeners with Normal Hearing and Sensorineural Hearing Loss.: Objective: Listeners with sensorineural hearing loss (SNHL) typically experience reduced speech perception, which is not completely restored with amplification. This likely occurs because cochlear damage, in addition to elevating audiometric thresholds, alters the neural representation of speech transmitted to higher centers along the auditory neuroaxis. While the deleterious effects of SNHL on speech perception in humans...περισσότερα »
Qualities of Single Electrode Stimulation as a Function of Rate and Place of Stimulation with a Cochlear Implant.
Qualities of Single Electrode Stimulation as a Function of Rate and Place of Stimulation with a Cochlear Implant.: Objectives: Although it has been shown previously that changes in temporal coding produce changes in pitch in all cochlear regions, research has suggested that temporal coding might be best encoded in relatively apical locations. The authors hypothesized that although temporal coding may provide useable information at any cochlear location, low rates of stimulation might provide better sound quality in apical regions that are more likely to encode temporal information i...περισσότερα »
Within- and Across-Subject Variability of Repeated Measurements of Medial Olivocochlear-Induced Changes in Transient-Evoked Otoacoustic Emissions.
Within- and Across-Subject Variability of Repeated Measurements of Medial Olivocochlear-Induced Changes in Transient-Evoked Otoacoustic Emissions.: Objectives: Measurement of changes in transient-evoked otoacoustic emissions (TEOAEs) caused by activation of the medial olivocochlear reflex (MOCR) may have clinical applications, but the clinical utility is dependent in part on the amount of variability across repeated measurements. The purpose of this study was to investigate the within- and across-subject variability of these measurements in a research setting as a step toward determi...περισσότερα »
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online ------------------------------ Early Release The Journal of Clinical Endocrinology & Metabolism ------------------------------ [image: Journal of Clinical Endocrinology & Metabolism masthead] ------------------------------ ------------------------------ The Journal of Clinical Endocrinology & Metabolism Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Accumulation and Changes in C... περισσότερα »
These new articles for Molecular Endocrinology are available online
These new articles for Molecular Endocrinology are available online ------------------------------ Early Release Molecular Endocrinology ------------------------------ [image: Molecular Endocrinology masthead] ------------------------------ ------------------------------ Molecular Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Molecular genetic regulation of Slc30a8/ZnT8 reveals a positive association with glucose tolerance Ryan K. Mitchell, et al. | Molecul...περισσότερα »
Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway
Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway: [image: journal.ppat.1005260.g001] by John Karijolich, Emma Abernathy, Britt A. Glaunsinger Short interspersed nuclear elements (SINEs) are highly abundant, RNA polymerase III-transcribed noncoding retrotransposons that are silenced in somatic cells but activated during certain stresses including viral infection. How these induced SINE RNAs impact the host-pathogen interaction is unknown. Here we reveal that during murine gammaherpesvirus 68 (MHV68) infection, rap...περισσότερα »
Mri analysis of 3d normal and post-glossectomy tongue motion in speech.
Mri analysis of 3d normal and post-glossectomy tongue motion in speech.: MRI ANALYSIS OF 3D NORMAL AND POST-GLOSSECTOMY TONGUE MOTION IN SPEECH. Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31;2013:816-819 Authors: Xing F, Murano EZ, Lee J, Woo J, Stone M, Prince JL Abstract Measuring the internal muscular motion and deformation of the tongue during natural human speech is of high interest to head and neck surgeons and speech language pathologists. A pipeline for calculating 3D tongue motion from dynamic cine and tagged Magnetic Resonance (MR) images during speech has been developed. T... περισσότερα »
Nasendoscopic evaluation of stress velopharyngeal insufficiency in wind musicians: a pilot study.
Nasendoscopic evaluation of stress velopharyngeal insufficiency in wind musicians: a pilot study.: CONCLUSION: Specific anatomical features and factors such as fatigue and stress may affect maintenance of velopharyngeal closure in persons with stress VPI. It is important that musicians with stress VPI are evaluated while playing their instrument. Future studies into stress VPI would benefit by including objective assessment components and some degree of quantifiable measurements. PMID: 25743606 [PubMed - indexed for MEDLINE] (Source: Medical Problems of Performing Artists)
Cepstral, Spectral and Time-Based Analysis of Voices of Esophageal Speakers
Cepstral, Spectral and Time-Based Analysis of Voices of Esophageal Speakers: Conclusion: This study showed that cepstral and spectral analyses are more effective than time-based analysis in examining the voice quality of alaryngeal speakers. The present findings are expected to contribute to establishing the baseline for voice quality characteristics in total laryngectomy patients.Folia Phoniatr Logop 2015;67:90-96 (Source: Folia Phoniatrica et Logopaedica)
These new articles for Endocrinology are available online
These new articles for Endocrinology are available online ------------------------------ Early Release Endocrinology ------------------------------ [image: Endocrinology masthead] ------------------------------ ------------------------------ Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Osteoblast-specific Overexpression of Human WNT16 Increases both Cortical and Trabecular Bone Mass and Structure in Mice Imranul Alam, et al. | Endocrinology | Nov 19, 2015... περισσότερα »
Effects of Repetitive Transcranial Magnetic Stimulation in the Rehabilitation of Communication and Deglutition Disorders: Systematic Review of Randomized Controlled Trials
Effects of Repetitive Transcranial Magnetic Stimulation in the Rehabilitation of Communication and Deglutition Disorders: Systematic Review of Randomized Controlled Trials: Conclusion: The benefits of the technique and its applicability in neurogenic disorders related to communication and deglutition are still uncertain. Therefore, other randomized controlled trials are needed to clarify the optimal stimulation protocol for each disorder studied and its real effects.Folia Phoniatr Logop 2015;67:97-105 (Source: Folia Phoniatrica et Logopaedica)
Schmerzmittel-Studien: Unterschied zwischen Placebo und Wirkstoff nimmt ab
Schmerzmittel-Studien: Unterschied zwischen Placebo und Wirkstoff nimmt ab: Dtsch med Wochenschr 2015; 140: 1725-1726 DOI: 10.1055/s-0041-107742 In letzter Zeit sind einige Studien mit neuen Analgetika gegen neuropathische Schmerzen gescheitert. Der Hauptgrund dafür scheint aber nicht die fehlende Wirksamkeit der Präparate zu sein, sondern ein zunehmender Placeboeffekt. Ein ähnliches Phänomen ist auch aus Studien mit Antidepressiva, Antipsychotika und Statinen bekannt. [...] © Georg Thieme Verlag KG Stuttgart · New York Article in Thieme eJournals: Table of contents | Abstract |... περισσότερα »
Feinnadelaspiration peripherer Lymphknoten
Feinnadelaspiration peripherer Lymphknoten: Dtsch med Wochenschr 2015; 140: 1756-1758 DOI: 10.1055/s-0041-107965 Periphere Lymphknotenschwellungen haben unterschiedliche Ursachen. Neben einer Lymphadenopathie bzw. Lymphadenitis im Zusammenhang mit infektiösen und nicht-infektiösen Entzündungen können sie Ausdruck einer lymphatischen Systemerkrankung oder des metastatischen Befalls durch solide Tumoren sein. Die Feinnadelaspiration peripherer Lymphknoten ist eine den Patienten kaum belastende Methode, die in kürzester Zeit und mit minimalem technischem Aufwand eine zuverlässige Aussage... περισσότερα »
COPD: Helicobacter pylori mit reduzierter Lungenfunktion assoziiert
COPD: Helicobacter pylori mit reduzierter Lungenfunktion assoziiert: Dtsch med Wochenschr 2015; 140: 1726- DOI: 10.1055/s-0041-107526 Weltweit sterben jedes Jahr 3 Millionen Menschen an den Folgen einer chronisch obstruktiven Lungenerkrankung (COPD). Systemische Infektionen spielen möglicherweise eine Rolle bei der Entstehung und Progression der Erkrankung. Insbesondere eine Helicobacter-pylori-Infektion kann den Verlauf der COPD negativ beeinflussen.
Bilateral hypoplasia of the coronoid process
Bilateral hypoplasia of the coronoid process: We found a rare case of bilateral hypoplasia of the coronoid process incidentally in a non-syndromic, healthy, 24-year-old man with no coexisting diseases, who had presented at accident and emergency with pain in the right side of his face after an road traffic accident. Maxillofacial radiographs and computed tomography (CT) were done, and showed a dysjunction of the right frontozygomatic suture and maxillary butress, and an inward, v-shaped, displacement of the arch. Initial radiographs showed missing coronoid processess and, as the zyg...περισσότερα »
Bismuth is a heavy metal used in bismuth iodoform paraffin paste (BIPP) antiseptic dressings
Bismuth toxicity in patients treated with bismuth iodoform paraffin packs: Bismuth is a heavy metal used in bismuth iodoform paraffin paste (BIPP) antiseptic dressings and in a number of other medical preparations. It can be absorbed systemically and cause toxicity. We report 2 cases of such neurotoxicity after it was used in operations on the jaws.
Microvascular reconstruction of facial defects
Microvascular reconstruction of facial defects in settings where resources are limited: The surgical treatment of defects caused by noma is challenging for the surgeon and the patient. Local flaps are preferred, but sometimes, because of the nature of the disease, there is not enough local tissue available. We describe our experience of free tissue transfer in Ethiopia. Between 2008 and 2014, 34 microsurgical procedures were done over 11 missions with the charity Facing Africa, predominantly for the treatment of defects caused by noma (n=32). The mean duration of operation was 442mi...περισσότερα »
Stage II and III esophageal cancer
Burden of spousal caregivers of stage II and III esophageal cancer survivors 3 years after treatment with curative intent: Abstract ObjectivesThe aim of this study is to examine caregiver burden of spousal caregivers of patients with esophageal cancer after curative treatment with neoadjuvant chemoradiation followed by resection and to assess factors associated with caregiver burden. MethodsIn this exploratory, cross-sectional study, spousal caregivers and patients were eligible if the caregiver was the patient's spouse and the patient had been treated with chemoradiation follo... περισσότερα »
Maternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters
Maternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters: Objective Subclinical hypothyroidism and isolated hypothyroxinaemia in pregnancy have been associated with an increased risk of gestational diabetes. We aimed to ascertain if these women have a worse metabolic phenotype than euthyroid pregnant women. Design, subjects and methods We recruited 956 healthy Caucasian women with singleton, non-diabetic pregnancies from routine antenatal clinics. Detailed anthropometric measurements (including BMI and skinfold thickness) and fast... περισσότερα »
Imaging of the parathyroid glands in primary hyperparathyroidism
Imaging of the parathyroid glands in primary hyperparathyroidism: Primary hyperparathyroidism (PHPT) is one of the most frequent endocrine diseases worldwide. Surgery is the only potentially curable option for patients with this disorder, even though in asymptomatic patients 50 years of age or older without end organ complications, a conservative treatment may be a possible alternative. Bilateral neck exploration under general anaesthesia has been the standard for the definitive treatment. However, significant improvements in preoperative imaging, together with the implementation o... περισσότερα »
Free flap transplantation using an extracorporeal perfusion device: First three cases
Free flap transplantation using an extracorporeal perfusion device: First three cases: Free flap transplantation may not be feasible in patients with inadequate or absent recipient vessels. We report successful mandibular composite reconstructions without anastomosis in three consecutive patients with vessel-depleted neck. Based on clinical reports describing early neovascularisation, temporary extracorporeal perfusion of flaps was maintained until the flaps had become independent from the extracorporeal blood supply.
Diverse Cutaneous Presentations of Langerhans Cell Histiocytosis in Children
Diverse Cutaneous Presentations of Langerhans Cell Histiocytosis in Children: A Retrospective Cohort Study: [image: cover.gif?v=1&s=5d7dd2236b5f012b4ee5ee4b] Background Langerhans cell histiocytosis (LCH) is a rare disease, frequently affecting young children. Procedure We performed a retrospective study in patients younger than 16 years old manifesting with skin symptoms, and documented their different cutaneous lesions and systemic symptoms. We compared subgroups of children with single-system, skin-only, and multisystem disease and sought signs predictive for multisystem dise... περισσότερα »
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer: • Increased glycolysis and PDK2 overexpression in head and neck cancer (HNC) cells were correlated with decreased sensitivity to cisplatin.• Dichloroacetate (DCA) shifted cellular bioenergetics from glycolysis to mitochondrial oxidative phosphorylation.• DCA induced ROS accumulation and activated downstream mitochondrial apoptotic signaling in HNC cells.• DCA significantly reversed cisplatin resistance in HNC cells in vitro and in vivo.
Multiple Cervical Artery Aneurysms with Congenital Scoliosis
Multiple Cervical Artery Aneurysms with Congenital Scoliosis: A 47 year old man with congenital scoliosis was admitted complaining of dizziness and progressively enlarging bilateral neck swellings over 3 years. The patient had widely spaced eyes and bilateral pulsatile neck masses. Computed tomographic angiography revealed that the bilateral vertebral, carotid, and basilar arteries were distorted by multiple fusiform aneurysms, with the extracranial internal carotid artery aneurysms (ICAs) measuring (length × transverse diameter) 4.2 × 3.0 cm on the left and 7.2 × 4.3 cm on the righ... περισσότερα »
B-1 B cell progenitors transiently and partially express keratin 5 during differentiation in bone marrow
Keratin 5 (K5) is a cytoskeletal protein in the epithelial cells of skin and esophagus, and is a predominant keratin of the basal and suprabasal cell layers of the epidermis by forming heterodimers with keratin 14. Although K5 is a good marker of epithelial cells, such as keratinocytes, it disappears during differentiation, indicating that K5 expression is transient during the lifespan of epithelial cells [1]. Tg neo-self-antigen driven by the K5 promoter, such as membrane-bound OVA (mOVA) in K5-mOVA Tg mice, has been used for studying the presentation of epidermal self-antigen or... περισσότερα »
An aberrant carotid artery in the temporal bone
An aberrant carotid artery in the temporal bone with fatal complication: We report the case of an 84-year-old female presenting with an aberrant ICA with cerebral air embolization caused by Eustachian tube air inflation (ETAI). High pressure of air inflation developed because of an aberrant ICA blocking the tympanic orifice of the Eustachian tube, with release of the high-pressure air into the aberrant ICA. It must be kept in mind that complications may occur not only during transtympanic treatment, but also in any treatment, such as ETAI, in aberrant ICA cases.
Nutritional deficiencies
*Nasal polyps - salicylate sensitivity* Catarrh, sinusitis, history of removal of tonsils or adenoids - milk intolerance *Poor healing - zinc deficiency* *Can't remember dreams - vitamin B6 deficiency* *Sugar craving, blood sugar swings, low blood sugar - chromium deficiency, carbohydrate intolerance and gut fermentation syndrome* *Pre-menstrual syndrome - magnesium, zinc and essential fatty acid deficiencies* *Glandular fever - inadequate liver detoxification mechanisms* *Sensory symptoms - B12, B1, magnesium deficiencies* *Mental symptoms - any B vitamin deficiency! Allergies, toxic st...περισσότερα »
Nutritional deficiencies - Head and Neck
MOUTH *pale fissured tongue - iron deficiency* *sore painful fissured tongue - vitamin B3 deficiency* *sore burning tongue and lips and peeling of lips - vitamin B2 deficiency* *swollen tongue with lateral teeth indentations - food intolerance* *painful sore tongue with a smooth appearance - folic acid deficiency* *cracked lips - vitamin B2 deficiency, thrush* GUMS *pyorrhoea - Co Q 10 deficiency* *bleeding gums - vitamin C deficiency* *gum disease - co Q 10, folica acid, vitamin C deficiency* SKIN OF FACE *greasy red scaly skin of face and sides of nose - vitamin B2 deficiency* *seborrhoei...περισσότερα »
Nutritional deficiencies
*This list has been compiled by Dr Patrick Kingsley - so thank you Patrick! * *I have added in a few of my own.* *Symptoms are actually better indicators of nutritional deficiency than signs - indeed a BMJ article pointed out that 80% of diagnoses are made on the history, 6% on signs and 6% on investigations (although they didn't say how the other 8% was accounted for!) Anyhow, the following can be pointers to deficiencies, but they do not apply in all cases.* HANDS *cold hands - magnesium deficiency, hypothyroidism, chronic fatigeu with low cardiac output* NAILS *white spots - minera... περισσότερα »
International Journal of Pediatric Otorhinolaryngology
Corrigendum to "Development and validation of a new Mandarin tone identification test" [Int. J. Pediatr. Otorhinolaryngol. 78 (2014) 2174–2182] The authors regret the error in the heading for Section 3: This should read "Phase II: evaluation of test–retest reliability, internal consistency reliability and sensitivity". Audiovisual spoken word recognition as a clinical criterion for sensory aids efficiency in Persian-language children with hearing loss The aim of this study was to examine the role of audiovisual speech recognition as a clinical criterion of cochlear implant or hearing ... περισσότερα »
Evaluation of iron and zinc levels in recurrent tonsillitis and tonsillar hypertrophy
Evaluation of iron and zinc levels in recurrent tonsillitis and tonsillar hypertrophy: The aim of this study is to look into the roles of iron and zinc metals in etiopathogenesis of recurrent tonsillitis and tonsillar hypertrophy by evaluating the levels of iron and zinc elements in the palatine tonsillar tissue. Vitamin D and tonsil disease – Preliminary observations David Reid1, Randall Morton, Lesley Salkeld, Jim Bartleycorrespondenceemail 1David Reid was the recipient of a Counties-Manukau District Health Board studentship. DOI: http://dx.doi.org/10.1016/j.ijporl.2010.11.012... περισσότερα »
Profiling of circulating microRNAs in patients with Barrett's esophagus and esophageal adenocarcinoma
GSE51410 Profiling of circulating microRNAs in patients with Barrett's esophagus and esophageal adenocarcinoma: *Contributors* : Pauline Bus ; Christine Kestens ; Fiebo J Ten Kate ; Wilbert M Peters ; Joost H Drenth ; Jeanine M Roodhart ; Peter D Siersema ; Jantine W van Baal *Series Type* : Other *Organism* : Homo sapiens miRNAs were extracted from plasma samples of healthy volunteers, patients with Barrett's esophagus and patients with esophageal adenocarcinoma. We used the Serum / Plasma Focus miRNA PCR panel (Exiqon, Denmark) to quantitate miRNA presence in the different patien... περισσότερα »
SSEA4 is a marker for chemotherapy resistance [miRNA]
GSE57704 SSEA4 is a marker for chemotherapy resistance [miRNA]: *Contributors* : Andrea Aloia ; Evgeniya Petrova ; Stefano Cairo ; Stefan Tomiuk ; Silvia Rüberg ; Olivier Deas ; David Agorku ; Andreas Bosio ; Jean-Gabriel Judde ; Olaf Hardt *Series Type* : Non-coding RNA profiling by array *Organism* : Homo sapiens By coupling PDX and cell surface marker screening technologies, we have identified distinct tumor cell sub-populations that are associated with tumor resistance to chemotherapy. In the majority of relapsed tumors, the percentage of the marker-positive cells shifted back ...περισσότερα »
In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome
GSE71718 In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome: *Contributors* : Kenneth R Eyring ; Brent S Pedersen ; Ivana V Yang ; David A Schwartz *Series Type* : Methylation profiling by high throughput sequencing *Organism* : Mus musculus Introduction: Prenatal and postnatal cigarette smoke exposure enhances the risk of developing asthma. Despite this as well as other smoking related risks, 11% of women still smoke during pregnancy. We hypothesized that cigarette smoke exposure during prenatal development generates long lasting differe... περισσότερα »
Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37
Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37: Vitamin D has immunomodulatory properties in the defence against pathogens. Its insufficiency is a widespread feature of cystic fibrosis (CF) patients, which are repeatedly suffering from rhinovirus (RV)-induced pulmonary exacerbations. To investigate whether vitamin D has antiviral activity, primary bronchial epithelial cells from CF children were pre-treated with vitamin D and infected with RV16. Antiviral and anti-inflammatory activity of vitamin D was assessed. RV and LL-37 levels were measu... περισσότερα »
Allergic bronchopulmonary aspergillosis complicating asthma
A randomised trial of glucocorticoids in acute-stage allergic bronchopulmonary aspergillosis complicating asthma: Whether use of high-dose steroids in acute-stage allergic bronchopulmonary aspergillosis (ABPA) is associated with superior outcomes is not known. Herein, we compare the efficacy and safety of two glucocorticoid protocols in ABPA. Treatment-naive ABPA subjects randomly received either high-dose or medium-dose oral prednisolone. The primary outcomes were exacerbation rates and glucocorticoid-dependent ABPA after 1 and 2 years, respectively, of treatment. The secondary e...περισσότερα »
Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia
Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia: Lung disease in patients with both primary ciliary dyskinesia (PCD) or cystic fibrosis (CF) is associated with impaired mucociliary clearance; however, clinical outcomes are typically worse in CF patients. We assessed whether CF and PCD patients differ in inflammatory response in the airways during pulmonary exacerbation. We first studied clinically stable PCD patients with a spectrum of bacterial pathogens to assess inflammatory response to different patho...περισσότερα »
Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis
Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis: The diagnosis of cystic fibrosis (CF) patients with allergic bronchopulmonary aspergillosis (ABPA) is clinically challenging, due to the absence of an objective biological test. Since blood basophils play a major role in allergic responses, we hypothesised that changes in their surface activation pattern discriminate between CF patients with and without ABPA. We conducted a prospective longitudinal study (Stanford cohort) comparing basophil activation test CD203c levels ... περισσότερα »
Sialendoscopy with the use of a syringe pump
Sialendoscopy with the use of a syringe pump: Sialendoscopy has emerged for more than two decades as a diagnostic and interventional method for salivary gland ductal pathologies. Innovative technologies applied for the development of endoscopes with reduced diameters, higher image quality and micro-instruments for use via the working channel have increased the therapeutic effectiveness of the method. 1, 2, 3 This article is protected by copyright. All rights reserved.
Hypoglossal nerve identification during head and neck surgery
Hypoglossal nerve identification during head and neck surgery: The hypoglossal nerve injury following head and neck surgery is a rare but debilitating complication. 1 The incidence in one large neck dissection series has been recorded at 0.42%. 2 Injury following other head and neck operations, such as submandibular gland excision, is less common. 3 This article is protected by copyright. All rights reserved. World J Surg Oncol. 2013; 11: 225. Published online 2013 Sep 12. doi: 10.1186/1477-7819-11-225 PMCID: PMC3847448 *Hypoglossal nerve monitoring, a potential application of i... περισσότερα »
Once Upon a Microscopic Slide The Story of Histology
Inaya Hajj Hussein Mohamad Raad Rawan Safa Rosalyn Jurjus and Abdo Jurjus from Anatomy Pathology via ola Kala on Inoreader http://ift.tt/1QxDydw via IFTTT
Advanced glycation end products induce skeletal muscle atrophy and dysfunction in diabetic mice via an RAGE-mediated AMPK-downregulated Akt Pathway Note suggested title change
Abstract Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations characterized by a less muscle mass, muscle weakness, and a reduced physical functional capacity. Accumulation of advanced glycation end products (AGEs), known to play a role in diabetic complications, has been identified in aging human skeletal muscles. However, the role of AGEs in diabetic myopathy remains unclear. Here, we investigated the effects of AGEs on myogenic differentiation and muscle atrophy *in vivo* and *in vitro*. We also evaluated the therapeutic potential of al... περισσότερα »
Patients in whom the non-invasive mechanical ventilation (NIMV) applied instead of the routine venturi face mask (VM) application
Non-invasive mechanical ventilation after the successful weaning: a comparison with the venturi mask via ScienceDirect Publication: Brazilian Journal of Anesthesiology (English Edition) Publication date: Available online 20 October 2015 *Source:*Brazilian Journal of Anesthesiology (English Edition) Author(s): Adıyeke Esra, Ozgultekin Asu, Turan Guldem, Iskender Altay, Canpolat Gamze, Pektaş Abdullah, Ekinci Osman Background and objectivesThis study compared the rates of acute respiratory failure, reintubation, length of intensive care stay and mortality in the patients in whom the non-...περισσότερα »
Quality of recovery after anaesthesia measured with QoR-40
: a prospective observational study via ScienceDirect Publication: Brazilian Journal of Anesthesiology (English Edition) Publication date: Available online 20 October 2015 *Source:*Brazilian Journal of Anesthesiology (English Edition) Author(s): Luís Guimarães-Pereira, Maria Costa, Gabriela Sousa, Fernando Abelha BackgroundQoR-40, a 40-item questionnaire on quality of recovery from anaesthesia, has been shown to measure health status after surgery. Our aim was to evaluate the incidence of poor quality of recovery in our Post Anaesthesia Care Unit and to compare their QoR-40 scores befo...περισσότερα »
Nasogastric tube placement by using GlideScope™ visualization vs. MacIntosh laryngoscope assistance
Comparing insertion characteristics on nasogastric tube placement by using GlideScope™ visualization vs. MacIntosh laryngoscope assistance in anaesthetized and intubated patients via ScienceDirect Publication: Brazilian Journal of Anesthesiology (English Edition) Publication date: Available online 20 October 2015 *Source:*Brazilian Journal of Anesthesiology (English Edition) Author(s): Wan Hafsah Wan Ibadullah, Nurlia Yahya, Siti Salmah Ghazali, Esa Kamaruzaman, Liu Chian Yong, Adnan Dan, Jaafar Md Zain Background and objectiveThis was a prospective, randomized clinical study to compar... περισσότερα »
Treatment of status migrainosus by general anesthesia
: a case report via ScienceDirect Publication: Brazilian Journal of Anesthesiology (English Edition) Publication date: September–October 2015 *Source:*Brazilian Journal of Anesthesiology (English Edition), Volume 65, Issue 5 Author(s): Artur Udelsmann, Priscila Saccomani, Elisabeth Dreyer, Alberto Luiz Cunha da Costa Background and objectivesThe status migrainosus is a complication of migraine characterized by severe headache for more than 72h that did not respond to treatment, with risk of stroke and suicide. Researches on treatment are directed to drugs that stimulate GABA receptors...περισσότερα »
Changes in the distance between carina and orotracheal tube
during open or videolaparoscopic bariatric surgery via ScienceDirect Publication: Brazilian Journal of Anesthesiology (English Edition) Publication date: September–October 2015 *Source:*Brazilian Journal of Anesthesiology (English Edition), Volume 65, Issue 5 Author(s): Giovani de Figueiredo Locks, Maria Cristina Simões de Almeida, Maurício Sperotto Ceccon, Karen Adriana Campos Pastório ObjectiveTo examine whether there are changes in the distance between the orotracheal tube and carina induced by orthostatic retractor placement or by pneumoperitoneum insufflation in obese patients un...περισσότερα »
Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182,6932607174
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182,6932607174
