Hearing preservation in cochlear implant recipients: A cross‐sectional cohort study

xlomafota13 shared this article with you from Inoreader Hearing preservation in cochlear implant recipients: A cross‐sectional cohort study Via Clinical Otolaryngology Abstract Objectives A surge of new developments and research regarding cochlear implants and hearing preservation resulted in several treatment options in the last 5 years. By reviewing our CI population of this period, we aimed to investigate hearing preservation rates and the effect of different treatment options on hearing preservation. Design Retrospectively, all adult cochlear implant recipients with preoperative residual hearing at lower frequencies (threshold <80 dB hearing level) in a single tertiary referral centre between 2015 and 2020 were analysed. Patients were classified into four groups based on their hearing preservation outcome. Subsequently, differences between the four groups regarding several patient dependent and independent factors were investigated. Results In this study, 140 patients were included, which is 46% of all adult CI recipients. Complete hearing preservation was achieved in 14 patients (10%), and complete loss of residual hearing in 48 patients (34%). The lateral wall array and local application of corticosteroids were associated with better hearing preservation. Intravenous corticosteroids, local hyaluronic acid and surgical experience had no effect on hearing preservation rates. Speech perception was not better in patients with residual hearing. Conclusion Approximately half of all adult cochlear implant recipients had residual hearing at lower frequencies before surgery. In current medical practice, only electrode choice seems to have a clear effect on hearing preservation rates. The majority of CI recipients lose their residual hearing after cochlear implantation. Much improvement in treating CI recipients is needed to preserve their residual hearing in the future. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Papillary mucinous metaplasia: a distinct precursor of mucinous adenocarcinoma of the endometrium

xlomafota13 shared this article with you from Inoreader Papillary mucinous metaplasia: a distinct precursor of mucinous adenocarcinoma of the endometrium Via International Journal of Clinical and Experimental Pathology Int J Clin Exp Pathol. 2022 Feb 15;15(2):83-87. eCollection 2022. ABSTRACT Mucinous adenocarcinoma of the endometrium is heterogeneous, consisting of endometrioid adenocarcinoma composed of >50% mucinous cells, low-grade mucinous adenocarcinoma, microglandular adenocarcinoma, and gastric (gastrointestinal)-type adenocarcinoma. Previous studies have reported that papillary mucinous metaplasia is a possible precancerous lesion of mucinous adenocarcinoma with frequent KRAS mutations. Recently, we encountered a case of pure mucinous adenocarcinoma of the endometrium with concurrent papillary mucinous metaplasia in a 35-year-old woman. She underwent 6-month hormonal therapy for atypical endometrial hyperplasia. A follow-up biopsy led to a diagnosis of mucinous adenocarcinoma; therefore, total hysterectomy was performed. The tumor showed abundant intracytoplasmic mucin and mild-to-moderate cytologic atypia with papillary architectu re. KRAS mutation analysis revealed a point mutation from GGT to GTT in codon 12. Although papillary mucinous metaplasia showed an overexpression of p16INK4, especially in the intragrandular papillary tufts, and a low MKi67 labeling index, overt mucinous adenocarcinoma with a loss of P16INK4a expression showed a high proliferating index of MKI67. The mass presented with stage ІA disease. During follow-up, the patient was stable and showed no recurrence. Considering the histologic similarity and incidence of KRAS mutations between papillary mucinous metaplasia and mucinous adenocarcinoma, papillary mucinous metaplasia may be a precancerous lesion for a subset of mucinous adenocarcinoma of the endometrium. PMID:35265257 | PMC:PMC8902477 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Bilateral vertebral arteries arising distal to the left subclavian artery: embryological and anatomical description

xlomafota13 shared this article with you from Inoreader Bilateral vertebral arteries arising distal to the left subclavian artery: embryological and anatomical description Via radiol anat Surg Radiol Anat. 2022 Mar 9. doi: 10.1007/s00276-022-02903-0. Online ahead of print. ABSTRACT Abnormalities in the origin of vertebral arteries are relatively uncommon, but extremely rare when this abnormality happens on both sides. We present an anatomic variation in which both vertebral arteries came from the proximal descending thoracic aorta beyond the left subclavian artery with no other supra-aortic vessels accompanying the abnormality. The right vertebral artery took a retro-oesophageal course (lusoria artery), while the right and the left vertebral arteries enter the transverse foramina at the 7th cervical vertebra. From an embryological point of view, and overall controversial, this anomaly can be explained by the bilateral persistence of the 8th intersegmental artery as the origin of vertebral artery, instead of the dorsal segment of the 7th intersegmental artery being the origin, which is normally the case. The adequate identification of vertebral artery anomalies in complementary explorations is very important to avoid misdiagnosed vertebral occlusions or unexpected vertebral artery injuries during supra-aortic trunks, thyroid, and oesophagus open surgeries, among others, or even over the course of endovascular procedures. PMID:35266028 | DOI:10.1007/s00276-022-02903-0 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Defining the limits and indications of the Draf III endoscopic approach to the lateral frontal sinus and maximizing visualization and maneuverability: a cadaveric and radiological study

xlomafota13 shared this article with you from Inoreader Defining the limits and indications of the Draf III endoscopic approach to the lateral frontal sinus and maximizing visualization and maneuverability: a cadaveric and radiological study Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2022 Mar 9. doi: 10.1007/s00405-022-07323-9. Online ahead of print. ABSTRACT PURPOSE: The DRAF III procedure has been used for access to the lateralmost part of the frontal sinus. We sought to identify anatomical and radiological measurements as well as modifications that predict the lateral limits of visualization and surgical access after this procedure. METHODS: Seven cadaver heads were imaged with computed tomography scan. The distance from midline to the medial orbital wall (MOWD), midline to the lateral end of the frontal sinus (MLD), the sum of MLDs (SMLD), interorbital distance (IOD) and the shortest anteroposterior distance of the frontal recess (APD) were utilized. The ratios MLD/MOWD, and SMLD/IOD were calculated. The same distances were measured on 41 CT scans. Orbital transposition (OT) and partial resection of the piriform aperture (PAR) were performed; the visualization and reach were ass essed. The angle of insertion was measured before and after the modifications. RESULTS: Only the ratio MLD/MOWD was consistently predictive of access to the lateral, superior and posterior wall of the frontal sinus. Following the modifications, a visualization of 100% laterally was achieved with the 30- and 45 degree endoscopes and every lateral recess could be reached with the 70 degree suction. A mean increase of the angle of insertion of 25.3 and 59.6% was recorded after OT and PAR, respectively. CONCLUSIONS: IOD rather than APD defines the limits of the Draf III approach to the lateral frontal sinus and MLD/MOWD ratio can serve as a useful preoperative tool. Along to the already described OT, PAR increases visualization and reach of the lateral frontal sinus. PMID:35266026 | DOI:10.1007/s00405-022-07323-9 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Kaposiform Hemangioendothelioma of Internal Auditory Canal Presenting in 4-Week-Old Newborn

xlomafota13 shared this article with you from Inoreader Kaposiform Hemangioendothelioma of Internal Auditory Canal Presenting in 4-Week-Old Newborn Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This case report describes a rare case of a kaposiform heman gioendothelioma in the internal auditory canal of a 4-week-old newborn. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Quality Indicators for the Diagnosis and Management of Primary Hyperparathyroidism

xlomafota13 shared this article with you from Inoreader Quality Indicators for the Diagnosis and Management of Primary Hyperparathyroidism Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This quality improvement study develops quality indicator s to evaluate the diagnosis and treatment of primary hyperparathyroidism that could measure, improve, and optimize quality of care and outcomes for patients with this disease. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Chemosensory Psychophysical Evaluation of Gustatory Dysfunction in Patients With Long-Term COVID-19

xlomafota13 shared this article with you from Inoreader Chemosensory Psychophysical Evaluation of Gustatory Dysfunction in Patients With Long-Term COVID-19 Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cross-sectional study evaluates self-reported gustat ory dysfunction in patients with long-term COVID-19. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Development and Validation of a Novel At-home Smell Assessment

xlomafota13 shared this article with you from Inoreader Development and Validation of a Novel At-home Smell Assessment Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This diagnostic study develops and validates a simple scr eening assessment for olfactory dysfunction using common household items. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Possible Association between Lenvatinib Use and Primary Adrenal Insufficiency: Additional Studies Very Much Needed

xlomafota13 shared this article with you from Inoreader Possible Association between Lenvatinib Use and Primary Adrenal Insufficiency: Additional Studies Very Much Needed Via Clinical Thyroidology Clinical Thyroidology, Volume 34, Issue 3, Page 132-135, March 2022. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Is a 4-Day Low-Iodine Diet Sufficient for Radioactive Iodine Ablation in Differentiated Thyroid Cancer Treatment?

xlomafota13 shared this article with you from Inoreader Is a 4-Day Low-Iodine Diet Sufficient for Radioactive Iodine Ablation in Differentiated Thyroid Cancer Treatment? Via Clinical Thyroidology Clinical Thyroidology, Volume 34, Issue 3, Page 123-126, March 2022. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

18F–FDG–PET/CT May Reduce Unnecessary Thyroid Surgery in Cytologically Indeterminate Thyroid Nodules

xlomafota13 shared this article with you from Inoreader 18F–FDG–PET/CT May Reduce Unnecessary Thyroid Surgery in Cytologically Indeterminate Thyroid Nodules Via Clinical Thyroidology Clinical Thyroidology, Volume 34, Issue 3, Page 116-118, March 2022. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Prevalence of “Higher-Risk” Adverse Histological Features Found at Autopsy in Patients with Occult Differentiated Thyroid Cancer

xlomafota13 shared this article with you from Inoreader Prevalence of "Higher-Risk" Adverse Histological Features Found at Autopsy in Patients with Occult Differentiated Thyroid Cancer Via Clinical Thyroidology Clinical Thyroidology, Volume 34, Issue 3, Page 127-131, March 2022. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.