Mucormycosis in COVID-19 pandemic and its neurovascular spread

xlomafota13 shared this article with you from Inoreader Mucormycosis in COVID-19 pandemic and its neurovascular spread Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Oct 12:1-8. doi: 10.1007/s00405-021-07106-8. Online ahead of print. ABSTRACT PURPOSE: Rhinocerebral mucormycosis is a rapidly progressive angioinvasive fungal infection commonly seen in diabetics. In the COVID-19 pandemic we have witnessed a sudden surge in these cases. We aimed to evaluate the disease presentation, patterns of spread, and any association with the COVID-19 virus. METHODS: This prospective study was conducted on mucormycosis patients operated between March and July 2021. The diagnosis was confirmed either on KOH staining, fungal culture or histopathological examination. RESULTS: Thirty one cases (21 males, 10 females) with a mean age of 53.3 years were included, of which 9 (29.1%) were COVID positive on presentation, 17 (54.8%) were post-COVID, while 5 (16.1%) had radiological evidence of COVID sequelae. Most common symptoms were cheek numbness (87.1%), headache (83.9%), visua l disturbances (77.4%), and palate involvement (58.1%). Blackening of turbinates was uncommon (22.6%). Ethmoid sinus was involved in all patients. Pterygopalatine fossa involvement was present in 77.4%, and was accurately diagnosed on contrast enhanced MRI scan. There were 8 (25.8%) deaths, while the remaining are discharged or under treatment. CONCLUSION: An increase in the incidence of mucormycosis in the COVID-19 pandemic is probably due to a compromise in host immunity along with a synergistic effect in thrombotic microangiopathy. Spread of infection to the soft tissues of the infratemporal fossa, orbit or palate occur via neurovascular structures rather than by bone erosion. The pterygopalatine fossa is involved in most individuals. PMID:34637017 | PMC:PMC8506492 | DOI:10.1007/s00405-021-07106-8 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Voice Quality and Vocal Tract Discomfort Symptoms in Patients with COVID-19

xlomafota13 shared this article with you from Inoreader Voice Quality and Vocal Tract Discomfort Symptoms in Patients with COVID-19 Via Journal of Voice Dysphonia and laryngeal problems are some of the manifestations of the COVID-19 pandemic due to respiratory disease as a primary effect of COVID-19. The aim of the present study was to investigate voice quality and vocal tract discomfort symptoms in patients with COVID-19. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cerebrospinal Fluid Leaks Following Anterior Skull Base Trauma: A Systematic Review of the Literature

xlomafota13 shared this article with you from Inoreader Cerebrospinal Fluid Leaks Following Anterior Skull Base Trauma: A Systematic Review of the Literature Via leak of cerebrospinal fluid World Neurosurg. 2021 Oct 9:S1878-8750(21)01562-X. doi: 10.1016/j.wneu.2021.10.065. Online ahead of print. ABSTRACT BACKGROUND: Anterior skull base (ASB) fractures are reported in 4% of head injuries and represent 21% of all skull fractures. Cerebrospinal fluid (CSF) leaks may follow, severely exacerbating outcomes. We systematically reviewed the literature to analyze and compare the roles of endoscopic surgery, open surgery, and combined approaches in the management of CSF leak repair following post-traumatic ASB fractures. METHODS: PubMed, Web of Science, and Scopus databases were searched in accordance with the PRISMA guidelines. Studies reporting clinical data of patients with CSF leaks following ASB fracture were reviewed, focusing on management strategies and post-treatment outcomes. RESULTS: We included 29 articles comprising 888 patients. The average age at diagnosis was 34 years (range 18-91), with a male predominance (54 %) and a male/female ratio of 2.9:1 (647/241). Clinical data was available for 888 patients with CSF leaks post-ASB fracture, reporting a median follow-up time of 33.5 months (SD: ±29; range 0.5-330.0 months). Open surgical repair was the most common approach (67.9%), followed by endoscopic surgical repair (32.1%). The endoscopy cohort showed lower rates of complications (0.7% vs. 11.1%) and fistula recurrence (2.8% vs. 5.3%) compared to open surgery. CONCLUSION: ASB fractures are frequently treated as late surgery, 24 hours from injury or later, especially for endoscopic surgery. The endoscopic approach is overall preferred, mostly because of its safety and effectiveness, offering lower failure rates than open surgery. PMID:34637942 | DOI:10.1016/j.wneu.2021.10.065 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

xlomafota13 shared this article with you from Inoreader Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review Via ear nose throat Ear Nose Throat J. 2021 Oct 12:1455613211051662. doi: 10.1177/01455613211051662. Online ahead of print. ABSTRACT We report two subjects with tracheobronchopathia osteochondroplastica (TO), including the clinical manifestations, histological findings, and clinical treatments, which were analyzed retrospectively. One patient with TO was a 60-year-old woman, and the other was a 47-year-old man. The main clinical manifestations were cough, chest pain, and dyspnea. Computed tomography (CT) ima ges showed that TO mainly occurred in the trachea and main bronchus. Histological analysis showed inflammatory exudation, squamous metaplasia, submucosal cartilaginous, and ossification. We present the two cases to increase physician and patient awareness of this benign disease and to improve their understanding of the disease manifestations and potential complications. PMID:34636258 | DOI:10.1177/01455613211051662 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Trends in contrast media research the last 100 years

xlomafota13 shared this article with you from Inoreader Trends in contrast media research the last 100 years Via radioactive iodine Acta Radiol. 2021 Oct 12:2841851211051014. doi: 10.1177/02841851211051014. Online ahead of print. ABSTRACT This review focuses on the trends in contrast media (CM) research published in Acta Radiologica during the last 100 years, since the first edition in 1921. The main topics covered are the developments of iodine- and gadolinium-based CM. Other topics include manganese-based CM for magnetic resonance imaging (MRI) and barium for the investigation of the alimentary tract. From a histori c point of view, special CM for use in cholegraphy and myelography are addressed in the review. Today, these imaging procedures are obsolete due to the development of computed tomography, MRI, and ultrasound. The historical use of radioactive thorium-based CM for angiography is also addressed. Furthermore, publications on adverse reactions to CM are reviewed. PMID:34636678 | DOI:10.1177/02841851211051014 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expanding indication of free hypothenar flap transfer: Sequential pedicled ulnar palm flap transfer to a relatively large hypothenar flap donor site

xlomafota13 shared this article with you from Inoreader Expanding indication of free hypothenar flap transfer: Sequential pedicled ulnar palm flap transfer to a relatively large hypothenar flap donor site Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2021 Sep 20:S1748-6815(21)00408-3. doi: 10.1016/j.bjps.2021.08.021. Online ahead of print. ABSTRACT BACKGROUND: Free hypothenar flap (HTF) transfer allows sensible soft tissue reconstruction of the fingertip. However, HTF is basically indicated for a relatively small soft tissue defect, as width of an HTF is limited up to approximately 20 mm to allow primary donor site closure. Combined with sequential local flap to an HTF donor site, a larger HTF can be used without the contracture risk. The aim of this study was to evaluate feasibility of free HTF transfer and sequential ulnar palm flap (UPF) transfer (HTF-UPF) for relatively large fingertip reconstructions. METHODS: Medical charts of patients who underwent HTF-UPF for fingertip reconstruction were reviewed. An HTF was designed transversely proximal to the proximal palmar crease, and a slightly smaller hemi-spindle-shaped UPF was designed longitud inally on the mid-lateral aspect of the ulnar palm; the UPF was used to close the HTF donor site. Patient and flap characteristics, intra-operative findings, and postoperative results were evaluated. RESULTS: Twelve patients with average age of 42.7 years were included. HTF-UPF procedure was performed on 12 fingers. HTF's length/width ranged from 45/20 to 70/40 mm (average, 52.5/32.1 mm). UPF's length/width ranged from 40/20 to 55/30 mm (average, 46.7/24.2 mm). Time for sequential UPF transfer ranged from 3 to 9 min (average, 5.1 min). All HTFs and UPFs survived without flap necrosis or scar contracture. Postoperative sensation was comparable with the contralateral fingertip. CONCLUSIONS: HTF-UPF procedure allows relatively large fingertip reconstruction with a minimum risk of HTF donor site contracture. PMID:34642064 | DOI:10.1016/j.bjps.2021.08.021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Atrial Fibrillation Is Not Associated With Sudden Sensorineural Hearing Loss

xlomafota13 shared this article with you from Inoreader Atrial Fibrillation Is Not Associated With Sudden Sensorineural Hearing Loss Via ear nose throat Ear Nose Throat J. 2021 Oct 12:1455613211042566. doi: 10.1177/01455613211042566. Online ahead of print. ABSTRACT OBJECTIVES: The aim of this study is to assess the association between atrial fibrillation (AF) and sudden sensorineural hearing loss (SSNHL). METHODS: This study was conducted by searching the longitudinal health insurance database of the Taiwan National Health Insurance Program for relevant information from January 1, 2000, to December 31, 2011. Patients with AF were ma tched with non-AF controls with a 1:1 strategy according to propensity scores. Multiple logistic regression analyses were performed to determine the risk of SSNHL. RESULTS: In total, 14 698 patients with AF were matched with the same number of non-AF patients as controls. After propensity score matching, the use of antiplatelet or anticoagulation medications and the occurrence of SSNHL were found to have a significant difference between AF and non-AF patients. The occurrence of SSNHL was found to be higher in men, those of 45 to 74 years old, and patients with hypertension in both AF and non-AF groups. Multiple logistic regression analyses revealed that male gender, age between 45 and 74 years, hyperlipidemia, and hypertension are risk factors for SSNHL. The use of aspirin was found to reduce the rate of SSNHL (odds ratio [OR]: 0.67, 95% CI: 0.49-0.94, P = .019), but AF was not found to be a risk factor for SSNHL (OR: 0.89, 95% CI: 0.64-1.23, P = .467). CON CLUSION: The association between AF and SSNHL is not significant. PMID:34641716 | DOI:10.1177/01455613211042566 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Preoperative SARS‐CoV‐2 Screening Fails to Detect Viral Particles Prior to Airway Surgery

xlomafota13 shared this article with you from Inoreader Preoperative SARS‐CoV‐2 Screening Fails to Detect Viral Particles Prior to Airway Surgery Via The Laryngoscope Abstract Objectives Children have higher rates of asymptomatic SARS-CoV-2 infections or milder courses of infection, and their carrier status may potentially impact viral transmission to those providing them care. The aim of this study is to compare the existing COVID-19 pre-operative screening protocols to the detection of SARS-CoV-2 viral particles in surgical samples. Methods We conducted a prospective study with consecutive convenience sampling of children undergoing adenoidectomy between January and April 2021. Total nucleic acid was extracted from adenoid tissue and real-time reverse transcription-polymerase chain reaction was conducted to test for presence of SARS-CoV-2 viral particles. Univariate logistic regression was used to summarize the effect size of variables of interest on the odds of having SARS-CoV-2 positive adenoid tissue. Results Forty adenoid samples were collected and 11 (27.5%) had a positive SARS-CoV-2 reverse transcriptase- polymerase chain reaction. Patients with positive adenoids were older (11.8 years vs 7.9 years, OR: 1.3, p=0.01) and more likely to have had a positive nasopharyngeal swab in the previous 90 days (4/11 or 36% vs 0). Conclusion This data is the first report on the presence of SARS-CoV-2 particles in pediatric adenoidectomy specimens, with a high percentage of patients showing evidence of viral particles within the adenoid. This finding calls in to question the utility of preoperative COVID screening protocols which have yet to be rigorously validated in asymptomatic patients and have the potential to delay patients' surgical care. This article is protected by copyright. All rights reserved. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A new technique for treating hiatal hernia with gastroesophageal reflux disease: the laparoscopic total left-side surgical approach

xlomafota13 shared this article with you from Inoreader A new technique for treating hiatal hernia with gastroesophageal reflux disease: the laparoscopic total left-side surgical approach Via Traditional dysphagia therapy BMC Surg. 2021 Oct 9;21(1):361. doi: 10.1186/s12893-021-01356-3. ABSTRACT INTRODUCTION: Although the traditional bilateral surgical approach to treat hiatal hernia (HH) with gastroesophageal reflux disease (GERD) can provide local protection of the vagus nerve, the integrity of the entire vagus nerve cannot be evaluated. Therefore, we developed and described the total left-side surgical approach (TLSA), which theoretically reduces injury to the vagus nerve, and described the detailed surgical procedure. METHODS: Initially, we performed a cadaver study to explore the characteristics of the vagus nerve. Then, we prospectively evaluated the TLSA in 5 patients with HH and GERD between June 2020 and September 2020. Demographic characteristics, surgical parameters, perioperative outcomes, and follow-up findings were analyzed. RESULTS: The TLSA was successfully used in five patients (40-64 years old), and no major complications were note d. The median total operative time was 114 min, median blood loss was 50 mL, and median postoperative hospital stay was 3.8 days. Gastrointestinal function recovered within 4 days of surgery in all the patients. The 6-month follow-up gastroscopy examination showed well-established gastroesophageal flap valves. Compared with the baseline results, the 6-month follow-up results showed lower values for the total GerdQ score (12.4 vs. 6.2) and the total esophageal acid exposure time (3.48% vs. 0.38%). Based on the European Organization for Research and Treatment of Cancer quality of life questionnaire-stomach module 52 results, the incidence of dysphagia and flatulence decreased over time after the TLSA. CONCLUSIONS: The TLSA provides a clear and broad surgical field, less trauma, and rapid recovery; moreover, it is technically simple. Although our results suggest that the TLSA provides safety and short-term efficacy and is feasible for patients with HH and GERD, long-term results from a larger clinical trial are needed to validate these findings. Trial registration ChiCTR2000034028, registration date is June 21, 2020. The study was registered prospectively. PMID:34627222 | DOI:10.1186/s12893-021-01356-3 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Syndrome d’Eagle à l’origine d’une sténose grave de la carotide interne

xlomafota13 shared this article with you from Inoreader Syndrome d'Eagle à l'origine d'une sténose grave de la carotide interne Via Laryngologie CMAJ. 2021 Oct 12;193(40):E1580-E1581. doi: 10.1503/cmaj.202803-f. NO ABSTRACT PMID:34642164 | DOI:10.1503/cmaj.202803-f View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Multiple Dural Arteriovenous Fistulas Presenting as Objective Pulsatile Tinnitus and Evaluated Using Four-Dimensional Contrast-Enhanced MR Angiography

xlomafota13 shared this article with you from Inoreader Multiple Dural Arteriovenous Fistulas Presenting as Objective Pulsatile Tinnitus and Evaluated Using Four-Dimensional Contrast-Enhanced MR Angiography Via ear nose throat Ear Nose Throat J. 2021 Oct 13:1455613211049842. doi: 10.1177/01455613211049842. Online ahead of print. NO ABSTRACT PMID:34643457 | DOI:10.1177/01455613211049842 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.