Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Κυριακή 17 Ιανουαρίου 2021

Craniofacial Surgery

The Conundrum of Human Osteoinduction: Is the Bone Induction Principle Failing Clinical Translation?
No abstract available

Transoral Approach to the Giant Deep Lobe Parotid Gland Pleomorphic Adenoma
Parapharyngeal space tumors are rare tumors that make up about 0.5% to 1% of all head and neck neoplasms. The majority of parapharyngeal space tumors, which are usually benign, consist of salivary gland tumors and neurogenic tumors. Although the transcervical, transparotid or transmandibular approach is generally preferred for the excision of these tumors, the transoral approach, which is more advantageous in terms of cosmetics and function, can be applied in selected cases. This article presents a case in which the giant pleomorphic adenoma originating from the deep lobe of the parotid gland is removed by transoral approach. Address correspondence and reprint requests to Omer Vural, MD, Department of Otolaryngology, Head and Neck Surgery, Baskent University, Bahcelievler Mh. Maresal Fevzi Cakmak Cad. 5. Sokak, No: 48 Cankaya/Ankara 06490, Turkey; E-mail: dromervural@gmail.com Received 1 August, 2020 Accepted 5 December, 2020 This is a case presentation study and it does not need ethical approval in our institution. Informed written consent was obtained from the patient before abscess drainage. The authors report no conflicts of interest. © 2021 by Mutaz B. Habal, MD.

Is Le Fort I Distraction Enough to Treat Severe Midface Hypoplasia?
Background: In severe cases of maxillary hypoplasia, Le Fort I distraction may be required for treatment. This study describes our experience with internal distraction devices and assesses our outcomes in patients with a negative overjet on average >15 mm. Methods: A retrospective review of patients with a history of cleft lip and/or palate who underwent Le Fort I distraction at our institution from 11/2007-11/2017 was performed. Data regarding demographics, procedural details and outcomes were collected and analyzed. Results: Twenty patients, 13 (65.0%) male and 7 (30.0%) female, were included. All (100%) patients had a history of cleft lip and/or palate and 2 (10.0%) of them had associated syndromes. All 20 patients underwent internal distraction. The average age at surgery was 17.8 years (range 15.2–20.7, SD 1.6 years). The average preoperative negative overjet was 19.27 mm (range 10–30, SD 5.63 mm). The mean total distraction length was 15.3 mm (range 0–30, SD 6.72 mm). There were no intraoperative complications, however, there were a total of 4 (20.0%) postoperative complications, 2 of which required reoperation due to device malfunction or displacement. 14 (70.0%) patients had repeat procedures to complete occlusal correction or correct relapse. Conclusions: Maxillary distraction alone was insufficient for correction of maxillary discrepancies averaging >15 mm. Instead, it's utility may be in positioning the maxilla for a more viable final advancement and fixation procedure, rather than being solely responsible for achieving normal occlusion during distraction. Address correspondence and reprint requests to Jeffrey A. Hammoudeh, MD, DDS, USC Keck School of Medicine, Associate Chief, Plastic and Maxillofacial Surgery, Associate Professor of Surgery, Craniofacial Surgeon, Director, Jaw Deformities Center, Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, 4650 Sunset Boulevard MS#96, Los Angeles, CA 90027; E-mail: Jhammoudeh@chla.usc.edu Received 15 September, 2020 Accepted 4 December, 2020 Dr. Jeffrey A. Hammoudeh has served as a KLS Le Fort I Internal Distraction Design Consultant. Presented at: ACPA's 76th Annual Meeting in Tucson, Arizona, April 9 – 13, 2019 The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). © 2021 by Mutaz B. Habal, MD.

Auricular Arteriovenous Malformation With Macrotia Treated With Transcatheter Arterial Embolization, Polidocanol Foam Sclerotherapy and Subsequent Otoplasty Following Resection
Auricular arteriovenous malformation (AVM) occasionally accompanies macrotia. Here, the authors report a case of AVM with macrotia that was treated with transcatheter arterial embolization, percutaneous sclerotherapy, and subsequent otoplasty following partial resection. A 46-year-old man presented with Schobinger stage III AVM. After transcatheter arterial embolization of the feeding arteries using n-butyl-2-cyanoacrylate, 9 sessions of sclerotherapy were performed using 3% polidocanol foam. Partial resection of the AVM nidus and subsequent otoplasty for ear reduction were performed at the age of 50 years. Two years later, the remnant nidus was resected and the protruding ear was surgically corrected. No recurrence was observed, and the enlarged ear was reduced at follow-up 6 months after the final operation. Address correspondence and reprint requests to Satoru Sasaki, MD, PhD, Department of Plastic and Reconstructive Surgery, Center for Vascular Anomalies, Tonan Hospital, Kita 4, Nishi 7, Chuo-ku, Sapporo, Hokkaido 060-0004, Japan; E-mail: satoru-s@tonan.gr.jp Received 28 October, 2020 Accepted 4 December, 2020 The authors have no conflicts of interest to disclose. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). © 2021 by Mutaz B. Habal, MD.

Overlooked Piece of Wood Served as a Vector Transmitting Clostridium Perfringens: A Case Report Emphasizing the Awareness of Gas-Forming Organisms in Posttraumatic Pneumocephalus
The radiological depiction of posttraumatic pneumocephalus is due to trapped air in most cases. Although rarely reported, it can also be the result of a gas-forming organism, requiring immediate treatment due to high mortality. Here, we report on an elderly patient with radiological appearance of posttraumatic intracranial pneumocephalus after a wound was closed without recognition of a retained tree branch. The piece of wood served as a vector for transmission of Clostridium perfringens causing the collection of abnormal intracranial air. Radical excision of temporal muscle tissue along with extensive evacuation of the brain abscess and targeted intravenous antibiotics resulted in minor morbidity. Although a piece of wood can easily be missed with current diagnostic imaging, it is crucial that both clinicians and radiologists are aware of the presence of air and its differential diagnosis in posttraumatic pneumocephalus, in order to allow timely treatment in this fatal disease. Address correspondence and reprint requests to PD Dr Lukas Andereggen, MD, University of Bern, Freiburgstrasse, 3010 Bern, Switzerland; E-mail: lukas.andereggen@dbmr.unibe.ch Received 15 August, 2020 Accepted 4 December, 2020 This work is original and has not been published elsewhere nor is it currently under consideration for publication elsewhere. The authors report no conflicts of interest. Informed consent was obtained from the patient. A copy of the written consent is available for review by the Editor of this journal. This study fulfills the requirements of the Ethics Commission of the canton of Bern, Switzerland, and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. © 2021 by Mutaz B. Habal, MD.

Effectiveness of Different Surgical Flap Delay Methods and Their Systemic Toxicities
Objective: The surgical flap delaying has been shown to be effective in preventing partial flap loss or in preparing larger flaps. However, there is no gold standard flap delay method in the literature. In this study, the authors aimed to compare 3 types of surgical delay methods to determine which model would increase more flap survival. The authors also investigated the effect of delay methods on circulating mononuclear leukocytes as a parameter of DNA damage. Methods: Twenty-four Sprague-Dawley male rats were divided into 4 groups. All subjects had a 10 × 3 cm modified McFarlane flap. Surface area measurements, biopsies, and blood samples were taken on the day of sacrification; 7th day for the control group and 14th day for delay groups. Results: Between incisional surgery delay groups, a significant difference was found in necrosis and apoptosis in the bipedicled group, and only necrosis in the tripedicled group compared to the control. In terms of DNA damage, it was found higher in all experimental groups than in the control group. Conclusions: Both incisional surgical delay procedures' results were meaningfully effective when only incisions were made without the elevation of flaps. In conclusion, bipedicled incisional surgical delay seems to be the most effective method in McFarlane experimental flap model whereas two-staged surgeries may increase the risk of systemic toxicity. Address correspondence and reprint requests to Kemalettin Yildiz, Associate Professor, Medical Faculty, Department of Plastic Reconstructive and Aesthetic Surgery, Bezmialem Vakif University; E-mail: yildizkemalettin@gmail.com Received 9 August, 2020 Accepted 4 December, 2020 The authors report no conflicts of interest. This study was approved by the Animal Experimentation Ethics Committee of University. (Approval codes: 2013–39). All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. © 2021 by Mutaz B. Habal, MD.

Infraorbital Nerve Decompression for Chronic Post Traumatic Neuralgia: A Novel Approach and Review of the Safety and Efficacy of Piezoelectric Surgery on Soft Tissues and Nerves
Chronic post traumatic infraorbital nerve (ION) hyperesthesia is a rare complication of orbital floor fractures. Surgical decompression of the ION has been reported to relieve chronic post traumatic infraorbital neuralgia. This case report describes a novel approach for ION decompression in a patient who suffered from chronic infraorbital neuralgia associated with a healed displaced orbital floor fracture. We used an intraoperative 3D image-guided navigation system to accurately localize the fracture site and employed piezoelectric surgery for nerve decompression. We further review the literature on the safety and efficacy of piezoelectric surgery on soft tissue and nerves. Address correspondence and reprint requests to Lambros K. Viennas, MD, Department of Surgery, Division of Plastic Surgery, Eastern Virginia Medical School, 825 Fairfax Avenue 6th floor, Norfolk, VA 23507; E-mail: viennalk@evms.edu Received 28 April, 2020 Accepted 4 December, 2020 Dr. Viennas has received honoraria as educational consultant for LifeNet Health. He is on the Speaker's Bureau for Stryker Endoscopy and has never received funding, shares, financial interest, honoraria or support from Stryker. Maxwell Wagner report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). © 2021 by Mutaz B. Habal, MD.

Fronto-Orbital Advancement and Posterior Cranial Vault Expansion Using Distraction Osteogenesis in Patients With Multiple Craniosynostosis
This study aimed to evaluate the treatment outcomes and the efficiency of techniques of fronto-orbital advancement (FOA) and posterior cranial vault expansion (PCVE) using distraction osteogenesis in patients with multiple craniosynostosis. We assessed the treatment results and outcomes of 8 patients with multiple craniosynostosis at the Kagoshima University Hospital between 2005 and 2019. Each 4 patients underwent FOA and PCVE, respectively, using distraction osteogenesis. The cranial volume and developmental quotient (DQ) were measured at the preoperative period and 1 year after surgery. The mean patient age at surgery was 22 months. The mean preoperative cranial volume was 1027 and 1071 cm3 in the FOA and PCVE groups, respectively. The mean preoperative DQ scores were 74 and 67, respectively. After 1-year of follow-up, the corresponding mean cranial volume became 1108 and 1243 cm3, respectively. The corresponding mean DQ scores also improved to 74 and 81, respectively. The postoperative follow-ups in all cases were uneventful, except for persistent epilepsy in 1 patient. Fronto-orbital advancement and PCVE using distraction osteogenesis might contribute to good outcomes in expanding cranial volume, cosmetic osteogenesis, and infantile development in patients with multiple craniosynostosis. Regarding the cranial volume expansion, especially, PCVE using distraction osteogenesis is more effective than FOA. Address correspondence and reprint requests to Tatsuki Oyoshi, MD, PhD, Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, 890-8520, Kagoshima, Japan; E-mail: tatsuki@m2.kufm.kagoshima-u.ac.jp Received 5 August, 2020 Accepted 4 December, 2020 The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). © 2021 by Mutaz B. Habal, MD.

Photobiomodulation to Treat Necrotizing Fasciitis
The spread of odontogenic infections associated with comorbidities, such as diabetes mellitus, can result in a potentially lethal complication, with rapid necrosis of the superficial fascia, necrotizing fasciitis. In this case report, a female patient, 52 years old, fasting blood glucose of 303 mg/dL with necrotizing fasciitis associated with type 2 diabetes mellitus in the left cervical-thoracic region. She was treated with antibiotics, cervicotomy, abscess drainage, and underwent 10 photobiomodulation sessions with 2 weekly applications of the red wavelength laser to correct tissue loss in the left cervical region. With the development of tissue healing, the formation of granulation tissue increased, absence of necrotic areas, contraction of the edges, and total wound repair. This case emphasizes the effectiveness of photobiomodulation to optimize healing and modulate the inflammatory pattern in the treatment of necrotizing fasciitis sequelae. Address correspondence and reprint requests to Dr Abrahão Cavalcante Gomes De Souza Carvalho, Alexandre Baraúna Street, 949, Rodolfo Teófilo, ZIP code: 60430-160, Dental Clinic 05, Fortaleza, Brazil; e-mail: abrahao@ufc.br Received 14 November, 2020 Accepted 2 December, 2020 The authors report no conflicts of interest. © 2021 by Mutaz B. Habal, MD.

Time Reduction by Prebending Osteosynthesis Plates Using 3D-Printed Anatomical Models, In Patients Treated With Open Reduction and Internal Fixation
Introduction: The incidence of facial bones fractures is 18 to 32 for each 100,000 inhabitants. The most affected population are young working people. Fractures are most commonly caused by assaults and motor vehicle accidents. Its cost of care reaches 1.06 billion dollars. Premodeling osteosynthesis plates with anatomical models can decrease surgical time, bleeding, and increase patient satisfaction. This study aims to evaluate the impact of premodeled osteosynthesis plates, using anatomical models in patients with facial fractures. Material and Methods: Patients with facial fractures treated by open reduction and internal fixation were included—Group A without premolding plates and Group B with premolding. The variables studied were: age, sex, etiology of the fractures, number of fractures, among other variables that reflect the quality of the results. Results: A total of 17 osteosynthesis plates were included in 6 patients. The age was 22 to 47 years; all patients were male. The maximum surgery time was 129 to 300 minutes. The average time to start work was 4.8 weeks. When comparing the variables between the groups, we found no difference between the groups for bleeding P = 0.24, the start of work P = 0.19, the time of surgery P = 0.082, or for osteosynthesis time P = 0.15. There was only a significant difference in patient satisfaction, P = 0.04. Conclusions: The evidence collected shows that premodeling the plates only improves patients' satisfaction among facial fractures treated by open reduction and internal fixation. Address correspondence and reprint requests to Marco Aurelio Rendón-Medina, MD, Hospital General "Dr. Rubén Leñero," Plan de San Luis -Salvador Díaz Mirón no number, Col. Santo Tomás, Miguel Hidalgo. ZC. México City, México; E-mail: dr.rendon1989@gmail.com, md_marm@hotmail.com Received 2 November, 2020 Accepted 2 December, 2020 All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The Human Investigation Committee (IRB) of the Hospital Ruben Leñero. The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). © 2021 by Mutaz B. Habal, MD.


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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Herpes simplex laryngitis: Comparison between pediatric and adult patients.

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Herpes simplex laryngitis: Comparison between pediatric and adult patients.

Int J Pediatr Otorhinolaryngol. 2020 Dec 24;142:110596

Authors: Bachrach K, Levi JR, Tracy LF

Abstract
OBJECTIVES: Infection with herpes simplex virus (HSV) typically causes limited oral and genital symptoms, however HSV can also affect the larynx and result in severe aerodigestive symptoms. Due to the rarity of HSV laryngitis, the symptoms and clinical course of are not well understood. This study aims to more completely characterize HSV laryngitis in order to aid clinicians in understanding and recognition of HSV laryngitis.
METHODS: Comprehensive literature search of MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews to identify articles relating to HSV laryngitis. Patient demographics, presenting signs and symptoms, treatment and clinical course were extracted from the selected manuscripts.
RESULTS: There were 31 studies on HSV laryngitis that identified 36 patients (17 pediatric, 19 adult). The average age for pediatric patients was 11 months (9 M, 8F) and 52 years for adults (11 M, 8F). In the pediatric population, stridor was more common at presentation in comparison to the adult population (p < .01). Adults more commonly presented with dysphagia (p = .03) and dysphonia (p < .01) Adult patients were significantly more likely to undergo tracheotomy than pediatric patients (p = .047). The mean length of inpatient hospital stay was 21.2 days in pediatric patients and 15.8 days for adult patients.
CONCLUSION: HSV laryngitis has a unique presentation in pediatrics and adults, but is nonspecific in both populations leading to delays in diagnosis and treatment. HSV laryngitis is associated with significant morbidity including multi-week hospital stay and risk for needing tracheostomy in both adults and pediatric population which demonstrates need for clinical awareness of this complication of HSV infection.

PMID: 33434698 [PubMed - as supplied by publisher]

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DNA methylation biomarkers in peripheral blood of patients with head and neck squamous cell carcinomas. A systematic review

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journal.pone.0244101.g001&size=inline

by Christian Sander Danstrup, Mette Marcussen, Inge Søkilde Pedersen, Henrik Jacobsen, Karen Dybkær, Michael Gaihede

Background

Head and neck squamous cell carcinomas (HNSCC) are often diagnosed in advanced stages. In search of new diagnostic tools, focus has shifted towards the biological properties of the HNSCC, and the number of different biomarkers under investigation is rapidly growing.

Objectives

The objective was to review the current literature regarding aberrantly methylated DNA found in peripheral blood plasma or serum in patients with HNSCC and to evaluate the diagnostic accuracy of these changes.

Methods

The inclusion criteria were clinical studies involving patients with verified HNSCC that reported findings of aberrantly methylated DNA in peripheral blood serum or plasma. We systematically searched PubMed, OVID Embase and Cochrane Library. In addition to the search, we performed forward and backward chaining in references and Web of Science. The protocol was registered in PROSPERO: CRD42019135406. Two authors independently extracted data. The quality and the risk of b ias of the included studies were assessed by the QUADAS-2 tool.

Results

A total of 1,743 studies were found eligible for screening, while ultimately seven studies were included. All studies were found to have methodological weaknesses, mainly concerning patient selection bias. The best individual marker of HNSCC was Septin 9 in plasma with a sensitivity of 57% and a specificity of 95%.

Conclusions

None of the aberrantly methylated genes found in the retrieved studies are applicable as single diagnostic markers for HNSCC and the best gene-panels still lack diagnostic accuracy. Future studies may benefit from newer sequencing techniques but validation studies with well-designed cohorts are also needed in the process of developing epigenetic based diagnostic tests for HNSCC.

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Intraoperative ketorolac for pediatric tonsillectomy

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This is in response to the Letter to the Editor for our publication "Intraoperative ketorolac for pediatric tonsillectomy: Effect on post-tonsillectomy hemorrhage and perioperative analgesia" submitted by Pinchman et al. (IJPORL-D-20-01791).

Int J Pediatr Otorhinolaryngol. 2020 Dec 28;:110588

Authors: Rabbani CC, Pflum ZE, Ye MJ, Gettelfinger JD, Sadhasivam S, Matt BH, Dahl JP

PMID: 33436271 [PubMed - as supplied by publisher]

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Red ear syndrome in children

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Red ear syndrome in children: Review of literature and report of three cases.

Int J Pediatr Otorhinolaryngol. 2021 Jan 06;142:110615

Authors: D'Amico A, Galati C, Manzo ML, Reina F, Nocera GM, Raieli V

Abstract
BACKGROUND: Red ear syndrome (RES) is a neurological syndrome that is characterized by attacks of redness and pain that is localized in the earlobe, accompanied by a burning sensation, swelling or otalgia. The exact pathophysiology of RES is not known. Several pediatric cases have been described. They show an extreme variability in clinical presentation and therapeutic response, and therefore there are numerous difficulties in the diagnostic-therapeutic approach and in the comprehension of the physiopathology. The goal of this report is to present three clinical cases of red ear syndrome in children. These cases show various characteristics that can give useful indications regarding the differential diagnosis and the pathogenetic mechanisms that are involved, particularly when they are compared with cases published in the literature.
CASE-REPORTS: We report three pediatric RES cases: 1) a boy whose condition offered a typical example of the association that occurs between migraine and RES. 2) a girl with idiopathic RES. 3) a child who suffered RES attacks that showed many similarities with trigeminal autonomic cephalalgias.
CONCLUSION: Our clinical series shows the different ways in which RES can be expressed and they support the reported scientific literature. We suggest that the different forms of RES have a common final autonomic pathogenetic mechanism that is activated by parasympathetic hyperactivity and sympathetic inhibition. The different temporal characteristics, frequency, etc. may depend on the activation of distinct physiopathological modules that are related to the pain circuits, as suggested by the modular theory which describes that groups of neurons are defined as a module, where each module is responsible for a symptom and the individual's headache is defined by the activated modules.

PMID: 33440309 [PubMed - as supplied by publisher]

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Translation and validation of the LittlEars auditory questionnaire

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Translation and validation of the LittlEars auditory questionnaire in Kannada.

Int J Pediatr Otorhinolaryngol. 2020 Dec 31;142:110598

Authors: Umashankar A, B T, Prabhu P

Abstract
OBJECTIVE: The aim of the study was to translate and validate the LittlEARS Auditory Questionnaire (LEAQ) in Kannada.
METHOD: The translation procedure followed a traditional translation, back translation, and content validity process before administering. The finalized version was administered on 87 children with 67 normal hearing children and 20 hearing-impaired children.
RESULTS: The tool had good internal consistency, good reliability, and a norm curve could be established. The Cronbach alpha value for item correlation ranged from 0.26 to 0.79. A significant difference was found between normal hearing individuals and hearing impaired.
CONCLUSION: The LEAQ tool has been translated and validated for the Kannada speaking population and can be used as a screening tool for children up to two years of age and as a subjective outcome measuring tool for hearing aid and Cochlear Implant user.

PMID: 33440310 [PubMed - as supplied by publisher]

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PulmCrit- RCTs don’t justify using convalescent plasma or antibody cocktails

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Passive immunity refers to the infusion of antibodies (either polyclonal antibodies in the form of convalescent plasma, or engineered monoclonal antibodies).  The goal is to neutralize viral particles, reduce viral replication, and thereby improve clinical outcomes.  This is a promising theory, but it requires evidentiary support in the form of randomized controlled trials.  So far, […]

EMCrit Project by Josh Farkas.

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Protocol for outpatient management in cleft lip and palate repair.

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Protocol for outpatient management in cleft lip and palate repair.

Int J Pediatr Otorhinolaryngol. 2021 Jan 11;142:110592

Authors: Santos M, García J, Graf S, Giugliano C

Abstract
Cleft lip is a common malformation in Chile. The standard care for cleft lip and palate repair is inpatient admission; this is mainly to observe complications and administer intravenous fluids, antibiotics, and analgesics. In our center, however, a strict selection of patients undergo ambulatory surgeries. In this paper, we illustrate our experience managing outpatient cleft lip and palate repair and show that it is possible to carry out a successful ambulatory surgery with few to no complications in children and adults with cleft lip and palate.

PMID: 33444960 [PubMed - as supplied by publisher]

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Development of a novel mandibular distraction osteogenesis simulator using Computer Aided Design and 3D printing.

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Development of a novel mandibular distraction osteogenesis simulator using Computer Aided Design and 3D printing.

Int J Pediatr Otorhinolaryngol. 2021 Jan 04;142:110616

Authors: Reighard CL, Powell AR, Zurawski TY, Rooney DM, Keilin CA, Zopf DA

Abstract
INTRODUCTION: Micrognathia, a component of Robin Sequence, can cause glossoptosis, failure of palatal fusion, and critical obstruction of the airway. Mandibular distraction osteogenesis (MDO) is at times offered to anteriorly translate the mandible and tongue, relieving airway obstruction. MDO is an intricate reconstructive procedure that may be ideal for teaching using a high-fidelity educational simulator, allowing early hands-on experience in a zero-risk environment.
OBJECTIVES: To design a novel, low-cost, high-fidelity neonatal MDO simulator that can be used for trainee education and refinement of surgical technique.
METHODS: A novel MDO simulator was developed using additive manufacturing techniques. Three experts in MDO surgery completed a 20-item survey, rating the simulator's physical attributes, the realism of experience, the simulator's value, its relevance to practice and the surgeon's ability to perform tasks on a 4-point Likert scale.
RESULTS: Computer Aided Design (CAD) and 3D printing allowed for the production of a realistic surgical simulator that emulates important aspects of MDO surgery. This preliminary evaluation indicated adequate means across the five domains relevant to the simulator's fidelity and usability (M = 3.33 to 3.75) out of a maximum of 4 points. Lowest rated items were consistent with expert comments allowing future refinement on subsequent iterations. Consumable material costs per model were $9.39 USD.
CONCLUSIONS: The MDO model demonstrated adequate fidelity and holds promise as a skill-development tool for surgeons in training. Further studies are planned to determine its utility as a training and assessment tool.

PMID: 33444961 [PubMed - as supplied by publisher]

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Morbidity Associated With the Timing of Lymphadenectomy for Sentinel Lymph Node Metastasis in Melanoma: A Clarification Concerning the Available Evidence

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A. Piñero-Madrona
Actas Dermosifiliogr. 2021;112:97-8

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