Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Δευτέρα 3 Αυγούστου 2020

Medicine by Alexandros G. Sfakianakis


  •  British Journal of Oral and Maxillofacial Surgery...
  •  Stem Cells and DevelopmentMesenchymal Stem/Stroma...
  • [ASAP] Self-Assembly of Giant Mo<sub>240</sub> Hol...
  • Hydroxychloroquine (HCQ) use in G6PD deficient COV...
  • Enabling NMR studies of high molecular weight syst...
  • Human vulnerability to cancer malignancy is enhanc...
  •  International journal of pediatric otorhinolaryng...
  •  Nature Communications - current - nature.com scie...
  •  Clinical Oral InvestigationsEvaluation of sclerot...
  •  European Archives of Oto-Rhino-LaryngologyA compa...
  •  Surgical neurology internationalDouble neurophysi...
  •  Annals of NeurologyAlertness Training Improves Sp...
  •  Head and NeckEfficacy of toluidine blue in the di...
  •  Clinical GeneticsMicro and Martsolf syndromes in ...
  •  Anti-Cancer Drugs - Published Ahead-of-PrintImpac...
  •  BioMed Research InternationalAnalysis of Selected...
  •  Analytical Chemistry[ASAP] Tagging Transferrin Re...
  •  AllergyA mouse model of asthma‐chronic obstructiv...
  •  GeroScienceSleep, brain vascular health and agein...
  • Sci, Vol. 2, Pages 59: Informatics and the Challen...
  • Microorganisms, Vol. 8, Pages 1180: Mouse Abdomina...
  •  International Journal of Molecular SciencesIJMS, ...
  • Humanities, Vol. 9, Pages 71: Offshore Mysteries, ...
  • Cancers, Vol. 12, Pages 2149: Targeted Disruption ...
  • Antibiotics, Vol. 9, Pages 476: Genetic Determinan...







  • #
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
    Telephone consultation 11855 int 1193,

    Intralesional injection of triamcinolone hexacetonide as an alternative treatment for central giant cell lesions: a prospective study
    Publication date: Available online 2 August 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Renato Luiz Maia Nogueira, Rafael Lima Verde Osterne, Renata de Matos Brito Lima Verde, Nayana Oliveira Azevedo, Renata Cordeiro Teixeira, Roberta Barroso Cavalcante
    British Journal of Oral and Maxillofacial Surgery
    Mon Aug 03, 2020 20:45
    A note on working from home
    We have read with interest various recent papers published on working from home and how productive one can try to be or how to preserve health.1 2 Although we very much appreciate how the healthcare service has embraced innovation to continue to deliver patient care throughout a pandemic, we wish to highlight some of the challenges faced by many working from home.As the COVID-19 pandemic took hold, we acquired laptops with access to laboratory results, electronic patient notes, radiology and various...
    OEM Online First
    Mon Aug 03, 2020 19:00
    Clear cell papillary neoplasm of the breast with <em>MAML2</em> gene rearrangement: Clear cell hidradenoma or low-grade mucoepidermoid carcinoma?
    Publication date: Available online 2 August 2020Source: Pathology - Research and PracticeAuthor(s): Raima A. Memon, Carlos N Prieto Granada, Shi Wei
    ScienceDirect Publication: Pathology - Research and Practice
    Mon Aug 03, 2020 19:44
    Noise Exposure May Cause Even More Hearing Loss Than Doctors Thought
    By Nala RogersResearchers have long debated why so many people lose their hearing as they age. Some have argued that the problem lies mainly with the stria vascularis, a sort of battery in the inner ear that powers the transformation of sound energy into nerve impulses. But a new study places the blame largely with hair cells -- the same sensory organs that are damaged by loud noises.Most details of the inner ear are impossible to examine while people are alive. To really see what’s going on, researchers...
    Audiology
    Mon Aug 03, 2020 12:17
    Behind the Scenes of Disappointing Long Term EVAR Results: Pathophysiological Insights and Future Research Leads
    Publication date: Available online 2 August 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Jean Sénémaud, Raphael Coscas, Jean-Marc Alsac, Yves Castier, Quentin Pellenc, Jean-Baptiste Michel
    ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery
    Mon Aug 03, 2020 18:33
    Investigation of the Recognition Interaction Between Glycated Hemoglobin and Its Aptamer by Using Surface Plasmon Resonance
    Publication date: Available online 2 August 2020Source: TalantaAuthor(s): Dapeng Sun, Yi Wu, Shwu-Jen Chang, Ching-Jung Chen, Jen-Tsai Liu
    ScienceDirect Publication: Talanta
    Mon Aug 03, 2020 18:05
    Silica modification with 9-methylacridine and 9-undecylacridine as mixed-mode stationary phases in HPLC
    Publication date: Available online 2 August 2020Source: TalantaAuthor(s): Elham Sadat Hosseini, Kourosh Tabar Heydar
    ScienceDirect Publication: Talanta
    Mon Aug 03, 2020 18:05
    Imaging spectrum of NUT carcinomas
    Publication date: Available online 2 August 2020Source: Clinical ImagingAuthor(s): Mayur Virarkar, Mohammed Saleh, Nisha Subhashchandra Ramani, Ajaykumar C. Morani, Priya Bhosale
    Clinical Imaging
    Mon Aug 03, 2020 17:17
    Mammal functional diversity and habitat heterogeneity: Implications for hominin habitat reconstruction
    Publication date: September 2020Source: Journal of Human Evolution, Volume 146Author(s): W. Andrew Barr, Maryse Biernat
    Journal of Human Evolution
    Mon Aug 03, 2020 17:15
    The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy.
    The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy. Support Care Cancer. 2020 Aug 01;: Authors: Jovanovic N, Dreyer C, Hawkins S, Thouless K, Palma D, Doyle PC, Theurer JA Abstract PURPOSE: Patients treated for oropharyngeal cancer (OPC) are at increased risk for functional decline due to cancer-related impairments and treatment toxicities, often leading...
    Dysphagia - Rehabilitation
    Mon Aug 03, 2020 16:58
    Psychometrics of the Functional Oral Intake Scale for Children with Dysphagia.
    Psychometrics of the Functional Oral Intake Scale for Children with Dysphagia. J Pediatr Gastroenterol Nutr. 2020 Jul 28;: Authors: Yi YG, Shin HI Abstract OBJECTIVES: The functional oral intake scale (FOIS), developed for adults based on the categories of consumable food, has been adapted for infants. A FOIS for children is necessary, since oral motor development continues after one year of age. This study proposed a FOIS for children and...
    Dysphagia - Rehabilitation
    Mon Aug 03, 2020 16:58
    Sacral Tuberculosis
    Here is a case of 35 year Indian origin male with backache with MRI revealed marrow edema in the sacral vertebral bodies along with presacral abscess noted on sagittal fat suppressed images. Interestingly before the MRI Xray didnot show much changes. In patients with osteomyelitis, MRI will pick up the changes earlier than plain xray.MRI SHOWING SARCAL EDEMA & PRESACRAL ABSCESS                                        XRAY LS SPINE LATERAL VIEW  Famous Radiology Blog http://www.sumerdoc.blogspot.com...
    Radiology
    Mon Aug 03, 2020 15:03
    Quantitative gene expression dynamics of key placode signalling factors in the embryonic chicken scleral ossicle system
    Publication date: Available online 2 August 2020Source: Gene Expression PatternsAuthor(s): Jennifer L. Giffin, Tamara A. Franz-Odendaal
    Gene Expression Patterns
    Mon Aug 03, 2020 15:12
    Sex differences in impulsivity in adult rats are mediated by organizational actions of neonatal gonadal hormones and not by hormones acting at puberty or in adulthood
    Publication date: Available online 2 August 2020Source: Behavioural Brain ResearchAuthor(s): Jeffrey S. Darling, Daniel W. Bayless, Lauren R. Dartez, Joshua J. Taylor, Arjun Mehrotra, William L. Smith, Jill M. Daniel
    Behavioural Brain Research
    Mon Aug 03, 2020 15:01
    Prevalence of Body Dysmorphic Disorder among patients seeking orthodontic treatment
    Body Dysmorphic Disorder (BDD) is a psychiatric disorder with delusions about defects in appearance for which patients seek various treatments. Patients with BDD often seek cosmetic procedures, and orthodontic...
    Progress in Orthodontics - Latest Articles
    Mon Aug 03, 2020 03:00
    Autism treatment with stem cells: a case report
    OBJECTIVE: Autism Spectrum Disorder is a complex brain disorder and has multiple causes that occur in diverse combinations. There is a need to classify children with ASD at a very young age so that they can access evidence-based intervention that can significantly improve their outcomes. CASE REPORT: In this report we present a case of autism, which underwent intrathecal autologous bone marrow mononuclear cells transplantation along with neurorehabilitation. The primary goal of the treatment is...
    European Review » Neurology
    Mon Aug 03, 2020 13:34
    A standard technique with potential diagnostic value for estimating the quadriceps muscle strength of critically ill patients
    OBJECTIVE: Intensive care unit-acquired weakness (ICUAW) is common, and so far, there is no digital technology with a standard procedure to estimate the muscle strength of these patients. Quadriceps maximal isometric voluntary contraction (QMVC) is a precise and reliable procedure to detect quadriceps muscle strength. Therefore, this research aimed to explore whether QMVC measurements can be used in critically ill patients at the bedside as a potential diagnostic method. PATIENTS AND METHODS: Tailor-made...
    European Review » Neurology
    Mon Aug 03, 2020 13:34
    Clinical Outcomes Associated with the Use of Anticoagulant and Antiplatelet Agents in Patients Undergoing Treatment for Infective Endocarditis: A Pilot Study
    Publication date: Available online 2 August 2020Source: Clinical TherapeuticsAuthor(s): Sherin M. Pathickal, Tae Eun Park, Roopali Sharma
    Clinical Therapeutics
    Mon Aug 03, 2020 13:44
    Inverse association between serum endocan levels and small LDL and HDL particles in patients with type 2 diabetes mellitus
    OBJECTIVE: Determination of lipoprotein size and subclasses distribution can provide more significant information on cardiovascular disease risk than measurement of traditional lipid parameters alone. Accordingly, we aimed to examine their potential relationship with the novel biomarker of endothelial dysfunction, such as endocan in patients with type 2 diabetes mellitus (T2D), since there are no studies concerning this issue. PATIENTS AND METHODS: This case-control study included a total of 42...
    European Review » Metabolism
    Mon Aug 03, 2020 13:33
    Metformin doses and body mass index: clinical outcomes in insulin resistant polycystic ovary syndrome women
    OBJECTIVE: PCOS is the most common endocrinopathy among reproductive age women. Approximately 60% of PCOS women have insulin resistance. While the efficacy of metformin in reducing insulin resistance and decreasing androgen level has been widely validated, there is no agreement on the dose of metformin to be used. PATIENTS AND METHODS: Prospective non-randomized cohort study of 108 insulin resistant, overweight and obese PCOS women, aged between 22 and 35 years. All patients received 1500 mg of...
    European Review » Metabolism
    Mon Aug 03, 2020 13:33
    Serum and exosomal hsa_circ_0000907 and hsa_circ_0057362 as novel biomarkers in the early diagnosis of diabetic foot ulcer
    OBJECTIVE: Diabetic foot ulcer (DFU) is a serious chronic complication leading to disability and death in patients suffering from diabetes. Currently, there is no effective marker for its early diagnosis. The aim of this study is to analyze the difference of circRNA expression profiles between DFU and normal human wounds (NHW) and to screen serum biomarkers for the early diagnosis of DFU. MATERIALS AND METHODS: Differentially expressed circRNAs were screened by bioinformatics analysis, using GSE114248...
    European Review » Metabolism
    Mon Aug 03, 2020 13:33
    Spontaneous Regression of HCC- When the Immune System Stands Up to Cancer.
    Spontaneous Regression of HCC- When the Immune System Stands Up to Cancer. Hepatology. 2020 Aug 02;: Authors: Arjunan V, Hansen A, Deutzmann A, Sze DY, Dhanasekaran R Abstract Spontaneous regression of cancer is rare and has been observed mostly in immunogenic cancers like melanoma. A few cases of spontaneous regression of hepatocellular carcinoma (HCC) have been reported, but the mechanisms of regression have not been elucidated. Here, we...
    Rare Cancers
    Mon Aug 03, 2020 13:20
    A Rare Case of Vulvar Superficial Angiomyxoma in a Pediatric Patient.
    A Rare Case of Vulvar Superficial Angiomyxoma in a Pediatric Patient. J Pediatr Adolesc Gynecol. 2020 Jul 30;: Authors: O'Flynn O'Brien KL, Cortes-Santiago N, Patil NM, Bercaw-Pratt JL Abstract BACKGROUND: Superficial angiomyxoma (SAM) is a rare, benign cutaneous tumor. Originally described as a component of Carney Complex, it is now recognized as a sporadic condition. CASE: A 7-year-old female was referred for management of a 2.5...
    Rare Cancers
    Mon Aug 03, 2020 13:20
    Chemical shift imaging in the identification of those renal tumours that contain microscopic fat and the utility of multiparametric MRI in their differentiation
    Abstract Introduction The aim of this study was to assess the qualitative and MRI findings of renal tumours, to determine which lesions contain microscopic fat, one of the potential differentiating factors between tumour types. Methods 73 patients who underwent 3 Tesla MRI including chemical shift imaging, with subsequent biopsy or excision for histopathological diagnosis, were included in the study. The images were reviewed for a decrease in signal intensity (SI) on the opposed phase compared...
    Journal of Medical Imaging and Radiation Oncology
    Sun Aug 02, 2020 21:44
    Tract sealing with normal saline after percutaneous transthoracic lung biopsies – promising but better evidence required
    Journal of Medical Imaging and Radiation Oncology
    Sun Aug 02, 2020 17:08
    Respiratory syntycial virus: Current treatment strategies and vaccine approaches
    Antiviral Chemistry and Chemotherapy, Volume 28, Issue , January-December 2020. Respiratory Syncytial Virus is a yearly respiratory virus that causes significant frequencies of morbidities, particularly in the young and elderly populations. However, preventive vaccines and/or treatment therapies are generally lacking, although much attention is now being placed on this virus. Moreover, there are now multiple strategies currently being explored in a race to the first licensed vaccine. While vaccines...
    SAGE Publications Ltd: Antiviral Chemistry and Chemotherapy: Table of Contents
    Sun Aug 02, 2020 14:01
    Vascular risk factor control and adherence to secondary preventive medication after ischemic stroke
    Abstract Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischemic stroke. Methods 664 home‐dwelling participants in the Norwegian Cognitive Impairment After Stroke study, a multicenter observational study, were evaluated 3 and 18 months post‐stroke. We assessed medication adherence by self‐reporting (4‐item Morisky Medication Adherence...
    Journal of Internal Medicine
    Sun Aug 02, 2020 22:00
    Prucalopride in diabetic and connective tissue disease‐related gastroparesis: Randomized placebo‐controlled crossover pilot trial
    This study recruited 15 patients with gastroparesis (13 diabetic) who were given prucalopride 4 mg daily or placebo for 4 weeks in a randomized, double‐blind, placebo‐controlled crossover design. The primary outcome measures of symptoms were not different between groups. However, gastric emptying and bowel movement frequency were accelerated with prucalopride. The medication was well tolerated. Further study with larger sample sizes, and/or dose adjustment, is warranted. Abstract Background...
    The European Gastrointestinal Motility Society
    Sun Aug 02, 2020 21:05
    Histone H3K9 methylation regulates chronic stress and IL‐6–induced colon epithelial permeability and visceral pain
    Chronic stress increases levels of pro‐inflammatory cytokines, decreases GR transcriptional binding at epithelia cell tight junction gene promoters reducing tight junction gene expression, culminating in increased paracellular permeability and enhanced visceral pain sensation. Methylation of the repressive histone H3K9me2/me3 plays a central role in this process. Abstract Background Chronic stress is associated with activation of the HPA axis, elevation in pro‐inflammatory cytokines,...
    The European Gastrointestinal Motility Society
    Sun Aug 02, 2020 20:57
    Successful treatment of severe refractory post‐cesarean pyoderma gangrenosum with intravenous immunoglobulin
    Abstract Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by rapidly progressing necrolytic ulceration of the skin. Proper treatment is crucial since it can result in devastating consequences. First‐line treatments include systemic corticosteroids or cyclosporine. However, no standardized treatment regimens for refractory cases exist and treatment outcomes are affected by underlying conditions. PG after cesarean section, which is believed to occur in association with underlying...
    Wiley: Dermatologic Therapy: Table of Contents
    Sun Aug 02, 2020 20:55
    Comment on “Cutaneous Manifestations of Covid 19: A Case Report & a new finding from Egypt”
    Wiley: Dermatologic Therapy: Table of Contents
    Sun Aug 02, 2020 12:07
    Influences of Regulation of miR-126 on Inflammation,Th17/Treg Subpopulation Differentiation, and Lymphocyte Apoptosis through Caspase Signaling Pathway in Sepsis
    Abstract To observe the inflammatory response, differentiation of Th17/Treg subsets and apoptosis of lymphocytes, by regulating miR-126 in lymphocytes of septic rats. After using cecal ligation and puncture to establish sepsis model, miR-126 mimic and miR-126 inhibitor were used to transfect lymphocytes of septic rats in vitro and in vivo. ELISA was used to detect TNF-α, IL-6, IL-17, and IL-10, the differentiation of Th17 and Treg was...
    Latest Results for Inflammation
    Mon Aug 03, 2020 03:00
    Granulomatous skin infection from Iceland
    Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
    Sun Aug 02, 2020 21:27
    Topical sodium thiosulfate: a reliable treatment for digital calcinosis cutis – a case series with six patients
    Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
    Sun Aug 02, 2020 21:26
    Systemic immunosuppression in times of COVID‐19: Do we need to rethink our standards?
    Summary The current SARS‐CoV‐2 pandemic particularly endangers older people with pre‐existing cardiopulmonary and metabolic conditions. However, it is also currently under discussion whether patients under immunosuppressive therapy also have a higher risk of suffering a severe course of the COVID‐19 disease. In principle though, there is currently no data available for a general reduction or pause of immunosuppression in patients with autoimmune diseases because of the SARS‐CoV‐2 pandemic. However,...
    Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
    Sun Aug 02, 2020 21:26
    Bullous pemphigoid without detection of autoantibodies in a patient with psoriasis under ustekinumab
    Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
    Sun Aug 02, 2020 21:26
    Subcutaneous methotrexate for Hailey‐Hailey disease: two case reports and review of the literature
    Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
    Sun Aug 02, 2020 21:26
    Crestal Bone Changes and Patient Satisfaction with Single Implant‐Retained Mandibular Overdentures with Dalla Bona and Locator Attachments with Immediate Loading Protocols. A Randomized Controlled Clinical Study
    Abstract Purpose There is no enough evidence present on the success of single implant‐retained mandibular overdentures (SIMO) with Dalla Bona and Locator attachments. This study aims to compare crestal bone loss and patient satisfaction with SIMO with Dalla Bona and Locator attachment following immediate loading protocols. Material and Methods Twelve patients included in Group 1 received immediate SIMO with Dalla Bona attachments, and another twelve patients in Group 2 received immediate...
    Journal of Prosthodontics
    Sun Aug 02, 2020 21:05
    Sleep problems and depressive symptoms in toddlers and 8‐year‐old children: A longitudinal study
    Abstract Sleep and depression are interlinked throughout the lifespan, but very few studies have examined the directionality of the sleep–depression link in children. The aim of the current study was to prospectively examine the bidirectional association between sleep problems and internalizing problems and depressive symptoms in toddlers and children aged 1.5 and 8 years. Data stem from the large ongoing population‐based longitudinal study, the Norwegian Mother, Father and Child Cohort Study, recruited...
    Journal of Sleep Research
    Sun Aug 02, 2020 17:04

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