Antibiotics, Vol. 9, Pages 476: Genetic Determinants for Metal Tolerance and Antimicrobial Resistance Detected in Bacteria Isolated from Soils of Olive Tree Farms Antibiotics doi: 10.3390/antibiotics9080476 Authors: Nicolás Glibota Mª José Grande Antonio Galvez Elena Ortega Copper-derived compounds are often used in olive tree farms. In a previous study, a collection of bacterial strains isolated from olive tree farms were identified and tested for phenotypic antimicrobial resistance...
Antibiotics, Vol. 9, Pages 475: Antimicrobials as Single and Combination Therapy for Colistin-Resistant Pseudomonas aeruginosa at a University Hospital in Thailand Antibiotics doi: 10.3390/antibiotics9080475 Authors: Supanun Pungcharoenkijkul Jantima Traipattanakul Sudaluck Thunyaharn Wichai Santimaleeworagun Global infections with colistin-resistant Pseudomonas aeruginosa (CoR-PA) are increasing; there are currently very few studies focused on the antimicrobial susceptibility...
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Antioxidants, Vol. 9, Pages 702: An Off-Line DPPH-GC-MS Coupling Countercurrent Chromatography Method for Screening, Identification, and Separation of Antioxidant Compounds in Essential Oil Antioxidants doi: 10.3390/antiox9080702 Authors: Xiang Wang Guang-Lei Zuo Chao-Yue Wang Hyun Yong Kim Soon Sung Lim Sheng-Qiang Tong Essential oils are an important source of natural antioxidants and multiple methods have been established for evaluation of their overall antioxidant...
Antioxidants, Vol. 9, Pages 701: Circuits Regulating Superoxide and Nitric Oxide Production and Neutralization in Different Cell Types: Expression of Participating Genes and Changes Induced by Ionizing Radiation Antioxidants doi: 10.3390/antiox9080701 Authors: Patryk Bil Sylwia Ciesielska Roman Jaksik Joanna Rzeszowska-Wolny Superoxide radicals, together with nitric oxide (NO), determine the oxidative status of cells, which use different pathways to control their levels in response...
Antioxidants, Vol. 9, Pages 703: Enzymatic Antioxidant Signatures in Hyperthermophilic Archaea Antioxidants doi: 10.3390/antiox9080703 Authors: Emilia Pedone Gabriella Fiorentino Simonetta Bartolucci Danila Limauro To fight reactive oxygen species (ROS) produced by both the metabolism and strongly oxidative habitats, hyperthermophilic archaea are equipped with an array of antioxidant enzymes whose role is to protect the biological macromolecules from oxidative damage. The most...
Antioxidants, Vol. 9, Pages 700: Exploring the Use of Dimethyl Fumarate as Microglia Modulator for Neurodegenerative Diseases Treatment Antioxidants doi: 10.3390/antiox9080700 Authors: Rosito Testi Parisi Cortese Baiocco Di Angelantonio The maintenance of redox homeostasis in the brain is critical for the prevention of the development of neurodegenerative diseases. Drugs acting on brain redox balance can be promising for the treatment of neurodegeneration. For more...
Antioxidants, Vol. 9, Pages 699: Bioactive Polyphenols from Pomegranate Juice Reduce 5‑Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells Antioxidants doi: 10.3390/antiox9080699 Authors: Pepe Rapa Salviati Bertamino Auriemma Cascioferro Autore Quaroni Campiglia Marzocco Intestinal epithelial cells (IECs) play a pivotal role in maintaining intestinal homeostasis. Different noxious agents, among them also anticancer therapies,...
Antioxidants, Vol. 9, Pages 698: Phenylethyl Isothiocyanate Extracted from Watercress By-Products with Aqueous Micellar Systems: Development and Optimisation Antioxidants doi: 10.3390/antiox9080698 Authors: Ezequiel R. Coscueta Celso A. Reis Manuela Pintado Phenylethyl isothiocyanate (PEITC) was reported as a useful antioxidant, anti-inflammatory, and chemopreventive agent. Due to technological and stability issues, it is necessary to be able to extract PEITC from its natural matrix...
Antioxidants, Vol. 9, Pages 697: Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity Antioxidants doi: 10.3390/antiox9080697 Authors: Angela Gambelunghe Stefano Giovagnoli Alessandro Di Michele Simona Boncompagni Marco Dell’Omo Kerstin Leopold Ivo Iavicoli Vincenzo Nicola Talesa Cinzia Antognelli Gold nanoparticles (AuNPs) are considered nontoxic upon acute exposure, at least when they are equal...
Antioxidants, Vol. 9, Pages 696: Effect of Nanoconfinement of Polyphenolic Extract from Grape Pomace into Functionalized Mesoporous Silica on Its Biocompatibility and Radical Scavenging Activity Antioxidants doi: 10.3390/antiox9080696 Authors: Ana-Maria Brezoiu Laura Bajenaru Daniela Berger Raul-Augustin Mitran Mihaela Deaconu Daniel Lincu Anicuta Stoica Guzun Cristian Matei Mihaela Georgeta Moisescu Ticuta Negreanu-Pirjol The aim of this paper is to assess...
Antioxidants, Vol. 9, Pages 692: Antioxidants in Down Syndrome: From Preclinical Studies to Clinical Trials Antioxidants doi: 10.3390/antiox9080692 Authors: Noemí Rueda Revilla Carmen Martínez-Cué There is currently no effective pharmacological therapy to improve the cognitive dysfunction of individuals with Down syndrome (DS). Due to the overexpression of several chromosome 21 genes, cellular and systemic oxidative stress (OS) is one of the most important neuropathological processes...
Antioxidants, Vol. 9, Pages 694: Methanol Extract of Usnea barbata Induces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress Antioxidants doi: 10.3390/antiox9080694 Authors: Jen-Yang Tang Kuang-Han Wu Yen-Yun Wang Ammad Ahmad Farooqi Hurng-Wern Huang Shyng-Shiou F. Yuan Ru-In Jian Li-Yi Tsao Po-An Chen Fang-Rong Chang Yuan-Bin Cheng Hao-Chun Hu Hsueh-Wei Chang Some lichens provide the resources of common traditional...
Antioxidants, Vol. 9, Pages 693: Effects of Hydroxytyrosol against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Bovine Mammary Epithelial Cells: A Natural Therapeutic Tool for Bovine Mastitis Antioxidants doi: 10.3390/antiox9080693 Authors: Roberta Fusco Marika Cordaro Rosalba Siracusa Alessio Filippo Peritore Ramona D’Amico Patrizia Licata Rosalia Crupi Enrico Gugliandolo Background: Bovine mastitis is a growing health problem, affecting both...
Antioxidants, Vol. 9, Pages 695: Flavonoids with Glutathione Antioxidant Synergy: Influence of Free Radicals Inflow Antioxidants doi: 10.3390/antiox9080695 Authors: Igor Ilyasov Vladimir Beloborodov Daniil Antonov Anna Dubrovskaya Roman Terekhov Anastasiya Zhevlakova Asiya Saydasheva Vladimir Evteev Irina Selivanova This report explores the antioxidant interaction of combinations of flavonoid–glutathione with different ratios. Two different 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic...
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Atmosphere, Vol. 11, Pages 815: Evaluating Multiple WRF Configurations and Forcing over the Northern Patagonian Icecap (NPI) and Baker River Basin Atmosphere doi: 10.3390/atmos11080815 Authors: Marcelo Somos-Valenzuela Francisco Manquehual-Cheuque The use of numerical weather prediction (NWP) model to dynamically downscale coarse climate reanalysis data allows for the capture of processes that are influenced by land cover and topographic features. Climate reanalysis downscaling is...
Atmosphere, Vol. 11, Pages 819: Changes Detected in Five Bioclimatic Indices in Large Romanian Cities over the Period 1961–2016 Atmosphere doi: 10.3390/atmos11080819 Authors: Ștefana Banc Adina-Eliza Croitoru Nicoleta Afrodita David Andreea-Sabina Scripcă Bioclimatic indices are very important tools to evaluate the thermal stress of the human body. The aims of this study were to analyze the general bioclimatic conditions in ten big cities in Romania and to find out if there...
Atmosphere, Vol. 11, Pages 818: Statistical Analysis of Microphysical and Dynamical Parameters for Clouds and Precipitation over Nauq Tibetan Plateau in Summertime Using Ka-band Cloud Radar Atmosphere doi: 10.3390/atmos11080818 Authors: Liping Liu Wenhua Gao A Chinese Ka-band solid-state transmitter cloud radar (CR) was employed to investigate clouds and precipitation over the Tibetan Plateau (TP) in summer 2014. After performing quality control and merging the output from the three...
Atmosphere, Vol. 11, Pages 817: Air Quality Levels and Health Risk Assessment of Particulate Matters in Abuja Municipal Area, Nigeria Atmosphere doi: 10.3390/atmos11080817 Authors: Nathaniel Mopa Wambebe Xiaoli Duan This study focuses on assessing the health risk by particulate matter (PM) inhalation within the Abuja municipal area, Nigeria. Particulate matters (PM2.5 and PM10), HCHO and VOCs were collected by A handheld portable smart air quality detector BR-SMART-126. A hybrid single-particle...
Atmosphere, Vol. 11, Pages 816: Atmospheric Responses to Mesoscale Oceanic Eddies in the Winter and Summer North Pacific Subtropical Countercurrent Region Atmosphere doi: 10.3390/atmos11080816 Authors: Jianxiang Sun Suping Zhang Christopher J. Nowotarski Yuxi Jiang In the winter and summer North Pacific Subtropical Countercurrent region, the atmospheric responses to 20,000+ mesoscale oceanic eddies (MOEs) are examined using satellite and reanalysis data from 1999 to 2013. The...
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Behavioral Sciences, Vol. 10, Pages 125: Affective and Sexual Needs of Residents in Psychiatric Facilities: A Qualitative Approach Behavioral Sciences doi: 10.3390/bs10080125 Authors: Giulia Landi Mattia Marchi Mohamed Yassir Ettalibi Giorgio Mattei Luca Pingani Valentina Sacchi Gian Maria Galeazzi Background: The affective and sexual needs of psychiatric patients are often under-considered, although they contribute significantly to their general well-being. Such topics...
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Biology, Vol. 9, Pages 204: Leguminous Seeds Powder Diet Reduces the Survival and Development of the Khapra Beetle, Trogoderma granarium Everts (Coleoptera: Dermestidae) Biology doi: 10.3390/biology9080204 Authors: Spiridon Mantzoukas Georgia Korbou Alexandra Magita Panagiotis A. Eliopoulos Konstantinos Poulas Chemical storage pest control is interlinked with many challenges such as environmental pollution and toxicity to humans and animals. Alternative tools are thus being...
Biology, Vol. 9, Pages 203: Exercise Ameliorates Insulin Resistance of Type 2 Diabetes through Motivating Short-Chain Fatty Acid-Mediated Skeletal Muscle Cell Autophagy Biology doi: 10.3390/biology9080203 Authors: Ling Yang Haiqi Lin Wentao Lin Xiaoyang Xu Abstract: Background: Exercise can ameliorate type II diabetes mellitus (T2DM) by regulating intestinal flora metabolites. However, the detailed mechanism needs to be further explored. Methods: A...
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Biomedicines, Vol. 8, Pages 268: The Effectiveness of Multi-Session FMT Treatment in Active Ulcerative Colitis Patients: A Pilot Study Biomedicines doi: 10.3390/biomedicines8080268 Authors: Dorota Mańkowska-Wierzbicka Marta Stelmach-Mardas Marcin Gabryel Hanna Tomczak Marzena Skrzypczak-Zielińska Oliwia Zakerska-Banaszak Anna Sowińska Dagmara Mahadea Alina Baturo Łukasz Wolko Ryszard Słomski Agnieszka Dobrowolska The modification of the microbiome through...
Biomedicines, Vol. 8, Pages 270: Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting Strategies Biomedicines doi: 10.3390/biomedicines8080270 Authors: Gabriela Reyes-Castellanos Rawand Masoud Alice Carrier Cancer cells reprogram their metabolism to meet bioenergetics and biosynthetic demands. The first observation of metabolic reprogramming in cancer cells was made a century ago (“Warburg effect” or aerobic glycolysis), leading to the classical...
Biomedicines, Vol. 8, Pages 269: EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update Biomedicines doi: 10.3390/biomedicines8080269 Authors: Alessandro Fulgenzi Daniele Vietti Maria Elena Ferrero We have previously described the role played by toxic-metal burdens in the etiology of neurodegenerative diseases (ND). We herein report an updated evaluation of toxic-metal burdens in human subjects affected or not affected by ND or other chronic diseases....
Biomedicines, Vol. 8, Pages 267: Extracellular Vesicles (EVs) and Pancreatic Cancer: From the Role of EVs to the Interference with EV-Mediated Reciprocal Communication Biomedicines doi: 10.3390/biomedicines8080267 Authors: Sokviseth Moeng Seung Wan Son Jong Sun Lee Han Yeoung Lee Tae Hee Kim Soo Young Choi Hyo Jeong Kuh Jong Kook Park Pancreatic cancer is malignant and the seventh leading cause of cancer-related deaths worldwide. However, chemotherapy and radiotherapy...
Biomedicines, Vol. 8, Pages 271: Method Standardization for Conducting Innate Color Preference Studies in Different Zebrafish Strains Biomedicines doi: 10.3390/biomedicines8080271 Authors: Petrus Siregar Stevhen Juniardi Gilbert Audira Yu-Heng Lai Jong-Chin Huang Kelvin H.-C. Chen Jung-Ren Chen Chung-Der Hsiao The zebrafish has a tetrachromatic vision that is able to distinguish ultraviolet (UV) and visible wavelengths. Recently, zebrafish color preferences have...
Biomedicines, Vol. 8, Pages 264: PTEN, a Barrier for Proliferation and Metastasis of Gastric Cancer Cells: From Molecular Pathways to Targeting and Regulation Biomedicines doi: 10.3390/biomedicines8080264 Authors: Milad Ashrafizadeh Masoud Najafi Hui Li Ang Ebrahim Rahmani Moghadam Mahmood Khaksary Mahabady Amirhossein Zabolian Leila Jafaripour Atefe Kazemzade Bejandi Kiavash Hushmandi Hossein Saleki Ali Zarrabi Alan Prem Kumar Cancer is one of the life-threatening...
Biomedicines, Vol. 8, Pages 266: Phenol-Enriched Virgin Olive Oil Promotes Macrophage-Specific Reverse Cholesterol Transport In Vivo Biomedicines doi: 10.3390/biomedicines8080266 Authors: Lídia Cedó Sara Fernández-Castillejo Laura Rubió Jari Metso David Santos Daniel Muñoz-Aguayo Andrea Rivas-Urbina Mireia Tondo Karen Alejandra Méndez-Lara Marta Farràs Matti Jauhiainen Maria-José Motilva Montserrat Fitó Francisco Blanco-Vaca Rosa Solà Joan Carles...
Biomedicines, Vol. 8, Pages 265: High Carbohydrate 19-9 Antigen Serum Levels in Patients with Nonmelanoma Skin Cancer and Primary Occult Cancer Biomedicines doi: 10.3390/biomedicines8080265 Authors: Giulia Malaguarnera Saverio Latteri Roberto Madeddu Vito Emanuele Catania Gaetano Bertino Rosario Emanuele Perrotta Francesco Dinotta Michele Malaguarnera Background: Non-melanoma skin cancers (NMSC), despite having a favourable prognosis, present an increased risk of...
Biomedicines, Vol. 8, Pages 263: Nutritional Supplementation Concurrent with Nutrition Education Accelerates the Wound Healing Process in Patients with Diabetic Foot Ulcers Biomedicines doi: 10.3390/biomedicines8080263 Authors: Raedeh Basiri Maria T. Spicer Cathy W. Levenson Michael J. Ormsbee Thomas Ledermann Bahram H. Arjmandi Trials on nutritional supplements for the treatment of diabetic foot ulcer (DFU) have only evaluated the effects of supplementation with specific...
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Biomimetics, Vol. 5, Pages 37: Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation Biomimetics doi: 10.3390/biomimetics5030037 Authors: Francesco Nappi Antonio Nenna Francesca Lemmo Massimo Chello Juan Carlos Chachques Christophe Acar Domenico Larobina Ross operation might be a valid option for congenital and acquired left ventricular outflow tract disease in selected cases. As the pulmonary...
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Biomolecules, Vol. 10, Pages 1140: Development of Recombinant Immunotoxins for Hairy Cell Leukemia Biomolecules doi: 10.3390/biom10081140 Authors: Robert J. Kreitman Ira Pastan Hairy cell leukemia (HCL) is an indolent B-cell malignancy with excellent initial response to purine analogs pentostatin or cladribine, but patients are rarely, if ever, cured. Younger patients will usually need repeat chemotherapy which has declining benefits and increasing toxicities with each course. Targeted...
Biomolecules, Vol. 10, Pages 1139: Immunomodulatory Activities of Selected Essential Oils Biomolecules doi: 10.3390/biom10081139 Authors: Georg Sandner Mara Heckmann Julian Weghuber Recently, the application of herbal medicine for the prevention and treatment of diseases has gained increasing attention. Essential oils (EOs) are generally known to exert various pharmacological effects, such as antiallergic, anticancer, anti-inflammatory, and immunomodulatory effects. Current literature...
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Biosensors, Vol. 10, Pages 88: The Current Trends of Biosensors in Tissue Engineering Biosensors doi: 10.3390/bios10080088 Authors: Yi-Chen Ethan Li I-Chi Lee Biosensors constitute selective, sensitive, and rapid tools for disease diagnosis in tissue engineering applications. Compared to standard enzyme-linked immunosorbent assay (ELISA) analytical technology, biosensors provide a strategy to real-time and on-site monitor micro biophysiological signals via a combination of biological,...
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Brain Sciences, Vol. 10, Pages 514: Cerebral Substrates for Controlling Rhythmic Movements Brain Sciences doi: 10.3390/brainsci10080514 Authors: Naho Konoike Katsuki Nakamura Our daily lives are filled with rhythmic movements, such as walking, sports, and dancing, but the mechanisms by which the brain controls rhythmic movements are poorly understood. In this review, we examine the literature on neuropsychological studies of patients with focal brain lesions, and functional brain...
Brain Sciences, Vol. 10, Pages 515: Functional Network Mapping Reveals State-Dependent Response to IGF1 Treatment in Rett Syndrome Brain Sciences doi: 10.3390/brainsci10080515 Authors: Conor Keogh Giorgio Pini Ilaria Gemo Walter E. Kaufmann Daniela Tropea Rett Syndrome (RTT) is a neurodevelopmental disorder associated with mutations in the gene MeCP2, which is involved in the development and function of cortical networks. The clinical presentation of RTT is generally severe...
Brain Sciences, Vol. 10, Pages 513: Factors Influencing Central Nervous System Abnormalities in m.11778G>A Carriers Brain Sciences doi: 10.3390/brainsci10080513 Authors: Josef Finsterer With interest, we read the article by Jonak et al [...]
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Cancers, Vol. 12, Pages 2151: Germline Genetic Findings Which May Impact Therapeutic Decisions in Families with a Presumed Predisposition for Hereditary Breast and Ovarian Cancer Cancers doi: 10.3390/cancers12082151 Authors: Carolina Velázquez Kim De Leeneer Eva M. Esteban-Cardeñosa Francisco Avila Cobos Enrique Lastra Luis E. Abella Virginia de la Cruz Carmen D. Lobatón Kathleen B. Claes Mercedes Durán Mar Infante In this study, we aim to gain insight...
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