Furcation Measurements: Realities and Limitations.

Furcation Measurements: Realities and Limitations.

J Int Acad Periodontol. 2015;17(4):123-134

Authors: Sheridan RA, Wang HL, Eber R, Oh TJ

Abstract
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy. For the efficient clinical management of furcation defects, it is necessary to have a reliable diagnostic tool that can accurately measure and quantify the furcation defect. This article addresses the various diagnostic methods available and assesses their limitations. Further, it also highlights some new frontiers in the field of furcation diagnosis and measurements.

PMID: 26727151 [PubMed - as supplied by publisher]

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Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence.

Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence.

Trends Pharmacol Sci. 2015 Dec 22;

Authors: De Flora S, Ganchev G, Iltcheva M, La Maestra S, Micale RT, Steele VE, Balansky R

Abstract
Many drugs in common use possess pleiotropic properties that make them capable of interfering with carcinogenesis mechanisms. We discuss here the ability of pharmacological agents to mitigate the pulmonary carcinogenicity of mainstream cigarette smoke. The evaluated agents include anti-inflammatory drugs (budesonide, celecoxib, aspirin, naproxen, licofelone), antidiabetic drugs (metformin, pioglitazone), antineoplastic agents (lapatinib, bexarotene, vorinostat), and other drugs and supplements (phenethyl isothiocyanate, myo-inositol, N-acetylcysteine, ascorbic acid, berry extracts). These drugs have been evaluated in mouse models mimicking interventions either in current smokers or in ex-smokers, or in prenatal chemoprevention. They display a broad spectrum of activities by attenuating either smoke-induced preneoplastic lesions or benign tumors and/or malignant tumors. Together with epidemiological data, these findings provide useful information to predict the potential effects of pharmacological agents in smokers.

PMID: 26726119 [PubMed - as supplied by publisher]

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Furcation Measurements: Realities and Limitations.

Furcation Measurements: Realities and Limitations.

J Int Acad Periodontol. 2015;17(4):103-115

Authors: Karthikeyan BV, Sujatha V, Prabhuji ML

Abstract
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy. For the efficient clinical management of furcation defects, it is necessary to have a reliable diagnostic tool that can accurately measure and quantify the furcation defect. This article addresses the various diagnostic methods available and assesses their limitations. Further, it also highlights some new frontiers in the field of furcation diagnosis and measurements.

PMID: 26727149 [PubMed - as supplied by publisher]

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Marion Downs: Her life and legacy (1914-2014).

Related Articles

Marion Downs: Her life and legacy (1914-2014).

Int J Audiol. 2015 Apr;54(4):289-90

Authors: Northern JL

PMID: 25753499 [PubMed - indexed for MEDLINE]

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Angiogenesis inhibitor; +27 new citations

27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results:

Angiogenesis inhibitor

These pubmed results were generated on 2016/01/05

PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

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Economic consequences of workplace injuries in the United States: Findings from the National Longitudinal Survey of Youth (NLSY79)

Background

This study explored economic consequences of work-related injuries using a longitudinal data source.

Methods

Data were from the National Longitudinal Survey of Youth, 1979 cohort (n = 12,686). Short-term consequences were measured when the injury was reported. "Difference-in-differences" approach was applied to estimate income and wealth disparities between injured and non-injured workers before and after injury. Fixed effects models were used to identify variations over time.

Results

The annual earnings growth was $3,715 (in 2000 dollars) less for workers with DAFW injury and $1,152 less for workers with NDAFW injury compared to non-injured workers during a 10-year follow-up. Lost wages and disability following injury contributed to income loss for injured workers, but the loss was moderated by union membership. After controlling for confounders, income disparities persisted, but family wealth differences did not.

Conclusions

Occupational injuries exacerbate income inequality. Efforts to reduce such disparities should include workplace safety and health enforcement. Am. J. Ind. Med. © 2015 Wiley Periodicals, Inc.

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Serious injury and fatality investigations involving pneumatic nail guns, 1985–2012

Background

This article examines serious and fatal pneumatic nail gun (PNG) injury investigations for workplace, tool design, and human factors relevant to causation and resulting OS&H authorities' responses in terms of citations and penalties.

Methods

The U.S. Occupational Safety and Health Administration (OSHA) database of Fatality and Catastrophe Investigation Summaries (F&CIS) were reviewed (1985–2012) to identify n = 258 PNG accidents.

Results

79.8% of investigations, and 100% of fatalities, occurred in the construction industry. Between 53–71% of injuries appear to have been preventable had a safer sequential trigger tool been used. Citations and monetary penalties were related to injury severity, body part injured, disabling of safety devices, and insufficient personal protective equipment (PPE).

Conclusions

Differences may exist between construction and other industries in investigators interpretations of PNG injury causation and resulting citations/penalties. Violations of PPE standards were penalized most severely, yet the preventive effect of PPE would likely have been less than that of a safer sequential trigger. Am. J. Ind. Med. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

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