Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Δευτέρα 18 Δεκεμβρίου 2017

Systematic review of empirical studies on cyberbullying in adults: What we know and what we should investigate

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Publication date: Available online 17 December 2017
Source:Aggression and Violent Behavior
Author(s): Cristina Jenaro, Noelia Flores, Cinthia Patricia Frías
Cyberbullying is a worldwide phenomenon and most of our knowledge comes from studies with adolescent and younger populations. Adult populations have received scarce attention. The present study is a systematic review of empirical academic papers on cyberbullying in the adult population. An online databases search (CINHAL, PsycInfo, ERIC, Medline, Pubmed, and Web of Science) identified 3986 references that, in successive steps, were reduced to 90 studies published between 2004 and 2016 that met the inclusion criteria. Each study was analyzed regarding topic, methods, ages, and other general characteristics. In addition, the measures used to assess cyberbullying, the impact of cyberbullying, and the different roles of those involved in the studies with adult population were explored. Results showed that there is a need for studies conducted in locations other than university settings and that the variety of measures, as well as the different criteria utilized to identify the cyberbullied, cyberbullies, and bystanders makes it difficult to compare findings. There is a need for longitudinal studies and for evidence-based practices to deal with these violent and aggressive behaviors.



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Anatomical variant of the meniscus related to posterior junction: a case report

There are several reports on anatomical differences of the meniscus. However, there are only a few reports on abnormalities in both menisci and anatomical differences in anterior cruciate ligament insertions.

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Asynchronous Bilateral Ovarian Torsion: Three Cases, Three Lessons

Background. Ovarian torsion (OT) is a serious condition, and delay in surgical intervention may result in loss of the ovary. Children and adolescents who have suffered from ovarian torsion may be at risk for asynchronous torsion of the contralateral ovary. Study objective. Three cases of asynchronous bilateral ovarian torsion were reported to analyse clinical history of three patients, to review the current literature, and to draw a conclusion for future treatment. Design. Case reports and review of the literature. Result. When a prepubertal girl presents with an ovarian torsion, several considerations have to be taken in account in order to preserve her future fertility; in particular, the pediatric surgeon/gynecologist has to preserve as much as possible the twisted ovary in addition to considering the fate of the contralateral ovary. Summary and Conclusions. Pelvic pain in a young girl has always raised the clinical suspect of an ovarian torsion; the possibility of asynchronous bilateral ovarian torsion is rare, but it is described in the literature and has catastrophic consequences; this condition has to be known and treated in the proper way by pediatric surgeons as well as by gynecologists in order to maximize the future fertility of the young patients.

http://ift.tt/2APJJ83

The Gleason pattern 4 in radical prostatectomy specimens in current practice - Quantification, morphology and concordance with biopsy

Publication date: Available online 18 December 2017
Source:Annals of Diagnostic Pathology
Author(s): Maiara Ferreira de Souza, André Luis Cardoso de Azevedo Araujo, Mariana Trindade da Silva, Daniel Abensur Athanazio
PurposeThe upgrading of a prostate acinar adenocarcinoma grade group 1 (GG1) between needle biopsy and prostatectomy is common. The extent of high-grade tumor and cribriform morphology are currently suggested as prognostic factors.MethodsWe reviewed 159 prostatectomy specimens from a private laboratory and an academic/public institution in Salvador, Bahia.ResultsTumors signed as GG1 at biopsy were upgraded in 59% of all cases. These tumors showed a low frequency of non-focal extraprostatic extension (one case, 3%), extensive positive surgical margins (two cases, 6%) and seminal vesicle invasion (one case, 3%). Among GG2 and GG3 tumors at prostatectomy, the percentage of Gleason pattern 4 (Gp4) involving the gland at ≤1%, 2–5% and >5% was associated with extensive extraprostatic extension (9%, 8% and 42%, respectively) and seminal vesicle invasion (1%, 10% and 31%, respectively). The volume of Gp4 of ≤1ml, >1 to 2ml and >2ml was associated with extensive extraprostatic extension (8%, 26% and 38%, respectively), seminal vesicle invasion (2%, 21% and 33%, respectively) and non-focal positive surgical margins (12%, 26% and 29%, respectively). Some GG2 tumors (~20%) indeed showed at least one measurement of Gp4 higher than one quarter of GG3 carcinomas. Cribriform morphology showed no significant associations for other adverse pathologic prognostic factors.ConclusionUpgrading from GG1 to GG2 is associated with a very low frequency of morphologic features associated with poor prognosis. Routine quantification of Gp4 is feasible in radical prostatectomy products and seems to better stratify tumors regarding the association with other morphologic parameters of prognostic importance.



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Diagnostic difficulties in cases of papillary urothelial neoplasm of low malignant potential, urothelial proliferation of uncertain malignant potential, urothelial dysplasia and urothelial papilloma: A review of current literature

Publication date: Available online 17 December 2017
Source:Annals of Diagnostic Pathology
Author(s): Damian Jaworski, Łukasz Szylberg, Arkadiusz Gzil, Peter Stawinski, Andrzej Marszałek
Tumours of the urinary tract are the fifth most frequent type of cancer. The most common types are urothelial tumours, among which, non-invasive urothelial neoplasms represent 45% of all cases. The 2016 WHO classification of urinary tract tumours introduced new classifications of non-invasive lesions. Besides urothelial papilloma (UP) and papillary urothelial neoplasm of low malignant potential (PUNLMP), as described in the former classification, the new classification also includes new entities such as urothelial proliferation of uncertain malignant potential (UPUMP) and urothelial dysplasia (UD). Of the aforementioned, UPUMP is the lesion that most commonly progresses, but solely to non-invasive carcinomas. UD is associated with a high risk of progression to invasive carcinoma. Understanding the biological character, and establishing the correct differential diagnosis in cases of non-invasive, non-cancerous lesions of the urinary bladder, will be of importance in establishing outcome predictions for future patients. A systematic review of the current literature allows us to systematize genetic, morphologic and prognostic factors of such lesions. Moreover, the collected data provide the basis for a proposed diagnostic algorithm which facilitates quick and effective differential diagnoses in cases of non-invasive non-cancerous urinary bladder lesions.



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Cover Image

Thumbnail image of graphical abstract

The cover image, by Erez Shmuel Davidi et al., is based on the Original Article Cisplatin-conjugated gold nanoparticles as a theranostic agent for head and neck cancer, DOI: 10.1002/hed.24935.



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