Comparison of the efficacy and mechanisms of intranasal budesonide, montelukast, and their combination in treatment of patients with seasonal allergic rhinitis

International Forum of Allergy &Rhinology, EarlyView.


https://ift.tt/2o8gSHh

Fronto Ethmoidal Mucocele Associated with Type 4 Kuhn Cells

Abstract

A mucocele is an epithelial lined mucous containing sac completely filling the sinus and capable of expansion. We report a case with unilateral frontoethmoidal mucocele in relation with type IV Kuhn cell. A 26 year old man came to the ENT department at SDUMC, Tamaka, Kolar, presenting complaints of proptosis of left eye since 3 years. After detailed examination and investigations patient was Diagnosed to have mucocele of left frontoethmoidal region. Intraoperatively we found a rare picture of type IV kuhn cells completely seated in the frontal sinus. After externally assisted modified Lothrop's approach, marsupialization of mucocele was done in the nasal cavity and symptoms of the patient relieved. We state that, in cases of frontoethmoidal mucocele, externally assisted modified Lothrop procedure offers an alternative for endoscopic management of frontoethmoidal mucocele for the complete clearance of disease.

https://ift.tt/2P5TgPa

Hearing Improvement in Interposition Ossiculoplasty and Myringostapediopexy

Abstract

Chronic otitis media (COM) may lead to partial or complete loss of tympanic membrane and erosion of the ossicles. Ossicular chain reconstruction may be done by interposition ossiculoplasty or myringostapediopexy. The aim of our study was to determine the hearing outcome in interposition ossiculoplasty and myringostapediopexy using autologous incus or cortical bone graft in intact canal wall tympanoplasty. 64 patients with COM, who underwent interposition ossiculoplasty or myringostapediopexy were included in the study. Audiometric evaluation was done after 3 months after surgery and all patients were followed up for a period of 1 year. The hearing results were compared in terms of mean pre-op and post-op Air conduction thresholds, Air-Bone gap (ABG) and hearing gain or ABG closure. In this study the mean ABG closure for interposition ossiculoplasty and myringostapediopexy was 15.4 dB and 21.8 dB, respectively. Hearing gain with cortical bone graft was higher than hearing gains with incus in both the groups, but not statistically significant. Myringostapediopexy provides marginally better hearing gain compared to interposition ossiculoplasty. Aulogous incus, and cortical bone graft are suitable autologous materials for ossicular reconstruction and provide similar hearing outcome.

https://ift.tt/2MAgX5p

Access to Round Window Niche via Posterior Tympanotomy and Impact of Drilling Its Overhangs: A Cadaveric Descriptive Study

Abstract

We intended to study the morphological parameters of round window region and assess the gain in exposure achieved by drilling the round window niche overhang. The Exposure of the round window membrane (RWM) is of prime importance to carry out atraumatic electrode insertion for cochlear implantation. The anatomy of round window has been a subject of considerable debate in literature. Fifty-one Formalin preserved adult cadaveric temporal bones were micro-dissected to carry out an 'optimal' posterior tympanotomy to expose the round window region. The bony overhangs of round window niche (RWN) were next drilled to achieve maximal possible exposure the RWM without violating the annulus of the same. The exposure was classified as per St Thomas' Hospital classification. The round window could not be visualized in 3 bones (5.9%). The commonest morphology of RWN was dome shaped, found in 18 (37.5%) and that of the RWM was oval shaped, found in 14 (29.2%) bones. Pre drilling 41 bones had a > 50% exposure of RWM while post drilling > 50% exposure could be achieved in all the bones except the 3 bones in which RWN could not be visualized to begin with. The drilling of the RWN overhangs exposed RWM in entirety in 91.7% of bones with a visible morphology of RWN pre drilling. RWN and RWM exhibit varied morphology. Drilling of the round window niche overhangs can considerably enhance the exposure of RWM.

https://ift.tt/2LoW87w

Enhanced Therapeutic Effects of Human Mesenchymal Stem Cells Transduced with Superoxide Dismutase 3 in a Murine Atopic Dermatitis‐Like Skin Inflammation Model

Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2Nh3mw2

Mapping of conformational IgE epitopes of food allergens

Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2PDHooK

Pulmonary function and bronchial reactivity 4 years after the first virus‐induced wheezing

Allergy, Volume 0, Issue ja, -Not available-.


https://ift.tt/2wplMn8