Relation between hysterectomy, oophorectomy and the risk of incident differentiated thyroid cancer: the E3N cohort

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2quRM6x

A new ultrasound nomogram for differentiating benign and malignant thyroid nodules

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2QjJJVt

Activography reveals aberrant proteolysis in desquamating diseases of differing backgrounds

Experimental Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2RBDXix

Mitochondrial dysfunction in affected skin and increased mitochondrial DNA in serum from patients with psoriasis

Experimental Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2Pz11kD

Detection of fluid secretion of three‐dimensional reconstructed eccrine sweat glands by magnetic resonance imaging

Experimental Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2RC16RT

Prevalence of methicillin-resistant Staphylococcus aureus colonization in individuals from the community in the city of Sao Paulo, Brazil.

Related Articles

Prevalence of methicillin-resistant Staphylococcus aureus colonization in individuals from the community in the city of Sao Paulo, Brazil.

Rev Inst Med Trop Sao Paulo. 2018 Oct 22;60:e58

Authors: Bes TM, Martins RR, Perdigão L, Mongelos D, Moreno L, Moreno A, Oliveira GS, Costa SF, Levin AS

Abstract
Staphylococcus aureus (SA) is a commensal habitant of nasal cavities and skin. Colonization by community-acquired methicillin-resistant SA (CA-MRSA) is associated with infections in patients who have not been recently hospitalized. The aim of this study is to determine the prevalence of MRSA colonization in an outpatient population, currently unknown in Brazil. Three-hundred patients or caregivers from two teaching hospitals were included. A questionnaire was applied and nasal swabs were obtained from patients. Swabs were inoculated in brain heart infusion (BHI) with 2.5% NaCl and seeded in mannitol. Suspicious colonies were subjected to MALDI-TOF MS Microflex™ identification. Antimicrobial susceptibility test for oxacillin was performed for SA-positive samples by microdilution. Polymerase chain-reactions for detection of mecA and coA genes were performed for resistant samples. Data about MRSA carriers were compared with non-carriers. There were 127 S. aureus isolates, confirmed by MALDI-TOF. Only seven (2.3%) were MRSA and positive for mecA and coA genes. Factors associated with MRSA carriage were African ethnicity, skin diseases or antibiotic use. The majority of them were from Dermatology clinics. Prevalence of MRSA colonization in individuals from the community was low in our study (2.3%). This finding raises the hypothesis of inter-household transmission of SA, although we did not find any association between MRSA-colonization and the shared use of personal objects. Given the low prevalence of MRSA carriers observed, empirical antimicrobial coverage for MRSA in community-acquired infections should be not necessary.

PMID: 30365641 [PubMed - in process]

https://ift.tt/2PbNvDV

Postpartum Methicillin-Resistant Staphylococcus aureus Toxic Shock Syndrome Caused by a Perineal Infection.

Related Articles

Postpartum Methicillin-Resistant Staphylococcus aureus Toxic Shock Syndrome Caused by a Perineal Infection.

Case Rep Obstet Gynecol. 2018;2018:2670179

Authors: Deguchi Y, Horiuchi Y, Shojima K, Iwahashi N, Ikejima M, Ino K, Furukawa K

Abstract
Although toxic shock syndrome (TSS) is rare, multiorgan failure can occur without early identification and appropriate therapy. In particular, a few cases of postpartum TSS due to methicillin-resistant Staphylococcus aureus (MRSA) have been reported. Here, we describe a rare case in which a 32-year-old Japanese woman had TSS due to MRSA that was caused by a perineal infection after a normal vaginal delivery. Twelve days after giving birth to a healthy child, she was readmitted to our hospital due to a 2-day fever and perineal pain without uterine tenderness. She developed emesis and watery diarrhea on the night of admission. On the second day, a diffuse cutaneous macular rash appeared over her trunk. Laboratory data revealed deteriorated renal function and thrombocytopenia. Her history and clinical results were compatible with a typical course of TSS. Administration of ceftriaxone and clindamycin was started immediately after admission and was effective. The patient recuperated steadily over the next week with desquamation of the skin. MRSA was isolated from her vaginal discharge and was found to produce TSS toxin 1 (TSST-1). Furthermore, since MRSA was not detected in the nasal and vaginal cavity during pregnancy, it suggests that vaginal colonization can also occur postpartum and be the disease source in mothers. Therefore, MRSA infections should be considered when treating for postpartum TSS.

PMID: 30363971 [PubMed]

https://ift.tt/2D3RLxU