Epinephrine dispensings, allergy hospitalisations and the elimination of co‐payments in Sweden

http://bit.ly/2RqMHYf

Is Human Papilloma Virus Infection Linked to Periodontitis? A Narrative Review

Abstract

Purpose of Review

Research suggests that periodontal tissue might serve as a reservoir for oral human papillomavirus (HPV) infection, while another hypothesis is that chronic inflammation of the tissue might perpetuate an infection with oral HPV infection. In this narrative review, we summarize the evidence related to a potential association between oral HPV infection and periodontitis.

Recent Findings

Twelve articles were identified, and their key findings summarized. Studies vary in sample size, study population, study design, and methods for assessment of oral HPV and periodontitis. Although results are conflicting and still inconclusive, various studies have found an association between oral HPV infection and periodontitis, which is supported by biological plausibility.

Summary

Future longitudinal studies should further evaluate this association, using clinical definitions of oral HPV infection and periodontitis, and focusing on high-risk populations for oral HPV infection. Studying this association is important since periodontitis might help identify at-risk individuals for oral HPV infection and potentially HPV-related oropharyngeal cancers.

http://bit.ly/2ThmoW5

Metaplastic basal cell carcinoma developing into syringomatous carcinoma: An enigmatic case report

http://bit.ly/2FYKMsC

Multiple pebble‐like ectopic nails as a subsequent complication of phenol cauterization treatment for onychocryptosis

http://bit.ly/2G8sxjM

Zinc transporters in the epidermis

http://bit.ly/2G98Qbr

Co‐existence of Juvenile dermatomyositis and psoriasis vulgaris with fungal infection: A case report and literature review

Summary

Introduction

The incidence rate of psoriasis vulgaris (PSV) coexisting with Juvenile dermatomyositis (JDM) is low. Through our thorough literature search, we found that PSV arising on JDM with superficial fungal infection of facial skin is rarely reported. So, we hereby, report a case of combination of the above three diseases. Meanwhile, we also reviewed the previous literatures aiming at the related basis, clinical manifestation, diagnosis, and treatment of the diseases. Interestingly, of all cases, this case is the only one in which the symptom of muscle weakness preceded the appearance of rash.

Case Presentation

A 21‐year‐old man diagnosed with JDM 6 years ago came to our inpatient department due to the appearance of new rash. Skin examination showed some sharply demarcated scaly plaques over the head, neck, torso, and bilateral upper limbs with pruritus and scaling. Histological examination and typical clinical manifestation confirmed the diagnosis of PSV for his new rash. Family history was negative for JDM and PSV. The clear erythema located on his face revealed the existence of superficial fungal infection with the help of fungal fluorescence microscopy. He had marked improvement of his symptoms with the treatment given at our department. In the past 3 months, the patient has been on regular follow‐up at our outpatient department, and his condition is stable at present.

Discussion

This paper presents a case of PSV arising on JDM coexisting with superficial fungal infection on the face hoping that this will help clinicians in the better diagnosis of the diseases during literature search.

http://bit.ly/2CPZn5A

Identification and validation of amino acid‐based mild exfoliating agents through a de novo screening method

Summary

Background

Due to internal or external factors, the desquamation (turnover) rate of the stratum corneum slows down, resulting in skin problems. Therefore, adjusting the exfoliation rate through cosmetics is an important issue.

Objective

This report aimed to develop exfoliating agents with lesser adverse effects and higher efficiency through an ex vivo screening method and in vivo turnover rate analysis of human skin.

Methods

Various molecules were evaluated by the ex vivo porcine skin exfoliation method and screened for their potential as effective agents. To confirm the effect and mechanism of each agent found, the exfoliation efficiency was evaluated. Each agent was also applied to the actual human skin to determine its efficacy and side effects.

Results

Despite the pH 6, carnitine and serine, which have similar or better efficiency compared to PHA, were selected. Based on the results, it was confirmed that calcium. And it is nonirritating to the human skin and increases the turnover rate (~130%).

Conclusion

Amino acid‐based exfoliating agents, such as carnitine and serine, were identified and verified to enhance the rate of exfoliation of the stratum corneum. It is expected that the improvement of dullness, mild acne, fine wrinkles, and pores through skin exfoliation in the field of cosmetics can be achieved safely through these agents.

http://bit.ly/2RY26V7