Pentito

I'm sorry I doubted it,and you were right, it waspartially because I'm prone to

http://bit.ly/2tp8fLk

Quality of Life in Prostate Cancer Patients Receiving Hypofractionated vs Conventional Radiotherapy

This phase 3 randomized clinical trial assesses differences in health-related quality of life between men with low-risk prostate cancer who are treated with hypofractionated vs conventional radiotherapy.

http://bit.ly/2GG4p8g

Trends in Smoking and e-Cigarette Use Among US Patients With Cancer, 2014-2017

This cross-sectional study of data from the National Health Interview Survey analyzes the prevalence of e-cigarette use in US patients with cancer.

http://bit.ly/2tm3YIl

Therapeutic Options for Neuroendocrine Tumors

This systematic review and meta-analysis examines randomized clinical trials to assess the safety and efficacy of medications used for patients with gastrointestinal and pancreatic neuroendocrine tumors.

http://bit.ly/2GG49WQ

Role of Monthly High-Dose Vitamin D Supplementation in Cancer Prevention

To the Editor Scragg et al address an issue of major current interest—the role of vitamin D in cancer prevention. We commend the authors for acknowledging several confounding factors in their study that could nullify any association between vitamin D and cancer incidence. These factors include the proportion of participants (approximately 25%) with vitamin D deficiency.

http://bit.ly/2tnFcI0

Role of Monthly High-Dose Vitamin D Supplementation in Cancer Prevention—In Reply

In Reply Peiris and colleagues commented on the null effect of vitamin D supplementation on incident cancer in the ViDA study, which is based primarily on possible differential effects on disease risk between daily vs monthly doses of vitamin D supplementation. In our article, we acknowledged that monthly dosing may be less effective than daily dosing for preventing cancer, and we agree that if this finding is true, increased variability in vitamin D levels associated with monthly dosing would be a possible mechanism. For example, daily or weekly dosing of vitamin D is more effective than bolus dosing (ie, monthly) in preventing acute respiratory infections, particularly in people with vitamin D deficiency. However, the recent null findings for incident cancer reported in the VITAL study, in which a daily dose of vitamin D was administered, suggest that the frequency of dosing is not important for cancer prevention.

http://bit.ly/2GLdDjB

Evaluating Risks and Benefits of Evolving Systemic Treatments of Neuroendocrine Tumors

In recent years, the number of treatments for metastatic, well-differentiated gastrointestinal and pancreatic neuroendocrine tumors (NETs) has expanded significantly. New medications for tumor control as well as symptom control include somatostatin analogues, everolimus, sunitinib, telotristat, and lutetium Lu 177 (¹⁷⁷Lu)-dotatate. These new therapies have been approved based on randomized clinical trials—an effort that has required international cooperation given the relative scarcity of metastatic NETs.

http://bit.ly/2tjZbXW