COVID-19 and anosmia: The story so far

xlomafota13 shared this article with you from Inoreader COVID-19 and anosmia: The story so far Via ear nose throat Ear Nose Throat J. 2021 Sep 29:1455613211048998. doi: 10.1177/01455613211048998. Online ahead of print. ABSTRACT OBJECTIVES: The pandemic has affected over 182 million coronavirus disease 2019 (COVID-19) cases worldwide. Accumulated evidence indicates that anosmia is one of the significant characteristics of COVID-19 with a high prevalence. However, many aspects of COVID-19-induced anosmia are still far from being fully understood. The purpose of this review is to summarize recent developments in COVID-19-induced anosmia to increase awareness of the condition. METHODS: A literature search was carried out using the PubMed, Embase, Web of Science, and Scopus. We reviewed the latest literature on COVID-19-induced anosmia, including mechanisms of pathogenesis, olfactory testing, anosmia as predictive tool, pathological examinations, imaging findings, affected factors, co-existing diseases, treatments, prognosis, hypothesis theories, and future directions. RESULTS: The possible pathogenesis of COVID-19-induced anosmia may involve inflammation of the olfactory clefts and damage to the olfactory epithelium or olfactory central nervous system by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The D614G spike variant may also play a role in the increased number of anosmia patients. Anosmia may also be an essential indicator of COVID-19 spread and an early indicator of the effectiveness of political decisions. The occurrence and develop ment of COVID-19-induced anosmia may be influenced by smoking behaviors and underlying diseases such as type 2 diabetes, gastroesophageal disorders, and rhinitis. Most patients with COVID-19-induced anosmia can fully or partially recover their olfactory function for varying durations. COVID-19-induced anosmia can be treated with various approaches such as glucocorticoids and olfactory training. CONCLUSION: Anosmia is one of the main features of COVID-19 and the underlying disease of the patient may also influence its occurrence and development. The possible pathogenesis of COVID-19-induced anosmia is very complicated, which may involve inflammation of the olfactory clefts and damage to the olfactory epithelium or olfactory central nervous system. PMID:34587819 | DOI:10.1177/01455613211048998 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Continuous Intraoperative Vasopressor Use in Head and Neck Free-Flap Reconstruction

xlomafota13 shared this article with you from Inoreader Continuous Intraoperative Vasopressor Use in Head and Neck Free-Flap Reconstruction Via JAMA Otolaryngology–Head & Neck Surgery Online First This cohort study investigates the association between continu ous vasopressor use and the incidence of reoperation in the early postoperative period for patients undergoing free-flap reconstruction. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Nonsurgical Risk Factors Associated With Pharyngocutaneous Fistula After Laryngectomy

xlomafota13 shared this article with you from Inoreader Nonsurgical Risk Factors Associated With Pharyngocutaneous Fistula After Laryngectomy Via JAMA Otolaryngology–Head & Neck Surgery Online First This multicenter cohort study of adult patients with laryngeal cancer uses data from a national database to identify nonclinical risks associated with the formation of pharyngocutaneous fistula after total laryngectomy. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

An Unusual Case of Bilateral Chylothorax After Neck Dissection

xlomafota13 shared this article with you from Inoreader An Unusual Case of Bilateral Chylothorax After Neck Dissection Via JAMA Otolaryngology–Head & Neck Surgery Online First This case report describes a woman in her 30s who underwent to tal thyroidectomy with modified radical neck dissection due to papillary thyroid cancer and was subsequently diagnosed with bilateral chylothorax secondary to cervical thoracic duct injury. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Levels of Triamcinolone Acetonide in Human Perilymph and Plasma After Intratympanic Application

xlomafota13 shared this article with you from Inoreader Levels of Triamcinolone Acetonide in Human Perilymph and Plasma After Intratympanic Application Via JAMA Otolaryngology–Head & Neck Surgery Online First This randomized clinical trial compares levels of triamcinolon e acetonide in perilymph and plasma after intratympanic injection. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Addressing the safety of hyaluronic acid dermal filler injections during the SARS CoV-2 pandemic worldwide vaccination

xlomafota13 shared this article with you from Inoreader Addressing the safety of hyaluronic acid dermal filler injections during the SARS CoV-2 pandemic worldwide vaccination Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2021 Sep 20:S1748-6815(21)00420-4. doi: 10.1016/j.bjps.2021.08.037. Online ahead of print. NO ABSTRACT PMID:34588152 | DOI:10.1016/j.bjps.2021.08.037 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study

xlomafota13 shared this article with you from Inoreader Clinical value of the Eustachian Tube Function Scoring System T-ETDQ: a prospective diagnostic study Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Sep 29. doi: 10.1007/s00405-021-07108-6. Online ahead of print. ABSTRACT PURPOSE: Tubomanometry (TMM) and the seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) was integrated to establish the Tubomanometry Eustachian Tube Dysfunction Questionnaire (T-ETDQ), and its reliability, potential clinical application, and diagnostic value for Eustachian tube function were investigated. METHODS: This prospective diagnostic study included patients visiting the ENT Department of our Hospital, between April and June 2021. Patients were grouped into Eustachian tube dysfunction (ETD) and control groups according to tympanometry diagnosis results. The diagnostic value of the T-ETDQ was evaluated using receiver-operating characteristic (ROC) curve analysis. RESULTS: There were 48 patients with Obstructive ETD and 24 patients without. The area under the ROC curve (AUC) of T-ETDQ was 0.898 (95% conf idence interval [CI] 0.826-0.969), and the highest sensitivity and specificity were 76.7% and 86.7% respectively when the positive cutoff value was 4.72. The AUC of Eustachian tube score (ETS) was 0.731 (95% CI 0.625-0.837) and the highest sensitivity and specificity were 48.3% and 90.0% respectively when the positive cut-off value was 4.5. The ETS and T-ETDQ had kappa values of 0.311 and 0.585, respectively (P < 0.001 for both), showing both methods were comparable to tympanometry; however, T-ETDQ had more consistent results than ETS. CONCLUSION: T-ETDQ can effectively quantify and evaluate ETD severity in adults, has a higher diagnostic value than ETS, making it a suitable diagnostic tool. PMID:34590179 | DOI:10.1007/s00405-021-07108-6 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.