Tender Nodules and Swollen Red Legs: Challenge

No abstract available

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Short Call Abstracts

Thyroid, Volume 28, Issue S1, Page A-169-A-198, October 2018.


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Short Call Author Abstract Index

Thyroid, Volume 28, Issue S1, Page A-199-A-202, October 2018.


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Chronic Viral Neuroinflammation: Speculation on Underlying Mechanisms

Viral Immunology, Ahead of Print.


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Type I Interferons in NeuroHIV

Viral Immunology, Ahead of Print.


https://ift.tt/2Q9CUFI

Diabetic Pulmopathy: A New Clinical Challenge for Diabetology

Exp Clin Endocrinol Diabetes 2018; 126: 590-591
DOI: 10.1055/a-0715-2743

© Georg Thieme Verlag KG Stuttgart · New York

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Reduced Anterolateral Thigh Flap Donor-Site Morbidity Using Incisional Negative Pressure Therapy

J reconstr Microsurg
DOI: 10.1055/s-0038-1672126

Background Primary closure of the donor-site after harvest of a large anterolateral thigh flap (ALT) is associated with significant morbidity. Incisional negative pressure therapy (INPT) may decrease complications in high-risk incisions. This study assessed if the incidence of complications after primary closure of the ALT flap donor-site decreases with INPT. Methods Retrospective cohort study of a prospectively maintained database including patients who underwent upper and lower limb reconstruction, using an ALT free flap with primary closure of the donor-site. Two groups were defined: primary closure and INPT (study group) and primary closure with traditional dressings (control group). Nonparametric statistics were employed to identify prognostic factors, p < 0,05. Results Fifty-eight free ALT flaps in 58 patients (study group n = 28; control group n = 30) were included. Median flap width and length were 9 cm (range: 5–14) and 25 cm (range: 10–48), respectively. Median follow-up was 19 months (range: 3–78 months). No significant differences in age or flap size were identified in both groups (p > 0.05). The global complication rate was 7.14% (n = 2) in the INPT group, and 37% (n = 11) in the control group (p = 0.007). The study group had a lower dehiscence and skin necrosis rate (p < 0.05). Multivariate logistic regression analysis showed IPNT was associated with a significant reduction of donor-site complications (p = 0.006), especially in patients with defects > 8 cm (p = 0.003). Conclusions In this cohort study the use of INPT significantly reduced the donor-site morbidity after ALT flap harvest.
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