Adolescent Presentation of Nasal Chondromesenchymal Hamartoma

xlomafota13 shared this article with you from Inoreader Adolescent Presentation of Nasal Chondromesenchymal Hamartoma Via JAMA Otolaryngology–Head & Neck Surgery Current Issue This case report describes an adolescent male who presented with a right-sided nasal mass after sustaining a concussion and was subsequantly diagnosed with a nasal chondromesenchymal hamartoma. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The impact and cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine into the paediatric immunisation programme in Iceland—A population-based time series analysis

xlomafota13 shared this article with you from Inoreader The impact and cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine into the paediatric immunisation programme in Iceland—A population-based time series analysis Via Otitis media by Elias Eythorsson, Tinna L. Ásgeirsdóttir, Helga Erlendsdóttir, Birgir Hrafnkelsson, Karl G. Kristinsson, Ásgeir Haraldsson Introduction Streptococcus pneumoniae is a cause of infections that range in severity from acute otitis media (AOM) to pneumonia and invasive pneumococcal disease (IPD). The 10-valent pneumococcal conjugate vaccine (PHiD-CV10) was introduced into the Icelandic paediatric immunisation programme in 2011. The aim was to estimate the population impact and cost-effectiveness of PHiD-CV10 introduction. Methods Data on primary care visits from 2005–2015 and hospitalisations from 2005–2017 were obtained from population-based registries. A Bayesian time series analysis with synthetic controls was employed to estimate the number of cases of AOM, pneumonia and IPD that would have occurred between 2013–2017, had PHiD-CV10 not been introduced. Prevented cases were calculated by subtracting the observed number of cases from this estimate. The cost of the programme was calculated accounting for cost-savings due to prevented cases. Results The introduction of PHiD-CV10 prevented 13,767 (95% credible interval [CI] 2,511–29,410) visits for AOM from 2013–2015, and prevented 1,814 (95%CI -523-4,512) hospitalisations for pneumonia and 53 (95%CI -17-177) admissions for IPD from 2013–2017. Visits for AOM decreased both among young children and among children 4–19 years of age, with rate ratios between 0.72–0.89. Decreases were observed in both pneumonia hospitalisations (rate ratios between 0.67–0.92) and IPD (rate ratios between 0.27–0.94). The total cost of implementing PHiD-CV10 in Iceland was -7,463,176 United States Dollars (USD) (95%CI -16,159,551–582,135) with 2.1 USD (95%CI 0.2–4.7) saved for every 1 USD spent. Conclusions The introduction of PHiD-CV10 was associated with large decreases in visits and hospitalisations for infections commonly caused by pneumococcus and was cost-saving during the first five years of the immunisation programme. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Surgical Removal of Hearing Aid Earmold Impression Material in the Middle Ear

xlomafota13 shared this article with you from Inoreader Surgical Removal of Hearing Aid Earmold Impression Material in the Middle Ear Via ear nose throat Ear Nose Throat J. 2021 Apr 8:1455613211009129. doi: 10.1177/01455613211009129. Online ahead of print. ABSTRACT When fitting hearing aids, patients are required to make an earmold impression material for device fixation. It usually causes no problems, although in rare cases, the earmold passes through the middle ear through tympanic membrane perforations.1-3 Foreign bodies may cause a delayed inflammatory reaction and deterioration of aeration, especial ly in the Eustachian tube. Herein, we report a rare case of earmold impression material as a foreign body in the middle ear that required surgical removal. PMID:33829882 | DOI:10.1177/01455613211009129 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Paranasal Mass in a Healthy Male Toddler

xlomafota13 shared this article with you from Inoreader Paranasal Mass in a Healthy Male Toddler Via ear nose throat Ear Nose Throat J. 2021 Apr 8:1455613211007944. doi: 10.1177/01455613211007944. Online ahead of print. ABSTRACT Head and neck tumors are rare in pediatric patients but should be kept in the differential when a patient presents with a new swelling or mass. One of these tumors is a myxoma, which is an insidiously growing, benign mass originating from the mesenchyme. They most commonly arise in the myocardium but can also develop in facial structures, particularly in the maxill a and mandible. When arising in facial structures, ocular, respiratory, and digestive systems can be affected based on local invasion. Complete surgical resection is curative but can lead to significant morbidity as well. Here, we present a case of a 15-month-old toddler presenting with a paranasal mass, which was ultimately diagnosed as a maxillary myxoma. This tumor is very rare in the pediatric population, especially in the toddler age-group, reminding clinicians to broaden the differential diagnosis when a patient's course is atypical. PMID:33829881 | DOI:10.1177/01455613211007944 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Frequent Recurrence of Sinonasal Inverted Papilloma With Carcinoma In Situ in a Multifocal Attachment Pattern: A Case Report and Review of the Literature

xlomafota13 shared this article with you from Inoreader Frequent Recurrence of Sinonasal Inverted Papilloma With Carcinoma In Situ in a Multifocal Attachment Pattern: A Case Report and Review of the Literature Via ear nose throat Ear Nose Throat J. 2021 Apr 8:145561321991344. doi: 10.1177/0145561321991344. Online ahead of print. ABSTRACT Sinonasal inverted papilloma (SIP) is a benign tumor originating from the nasal cavity and paranasal sinuses. Sinonasal inverted papilloma is characterized by local infiltration, high recurrence, and malignant transformation, and its associated dysplasia ranges from mild, moderate, severe, carcinoma in situ (CIS) to invasive squamous cell carcinoma. Sinonasal inverte d papilloma with carcinoma in situ (IPwCIS) is the highest degree of dysplasia, which is a stage of malignant transformation of IP. Surgical excision and proper adjuvant therapy can help reduce recurrence rates and suppress further deterioration. In this study, we present a patient with IPwCIS who developed 3 recurrences with a multifocal attachment pattern in less than 18 months. We report the clinical manifestations, development, and treatment process in detail. We also performed a literature review to analyze the characteristics of the disease. Despite comprehensive treatment methods, tumor recurrence and further deterioration of IPwCIS persist. PMID:33829884 | DOI:10.1177/0145561321991344 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Management of Multiple Head and Neck Paragangliomas With Assistance of a 3-D Model

xlomafota13 shared this article with you from Inoreader Management of Multiple Head and Neck Paragangliomas With Assistance of a 3-D Model Via ear nose throat Ear Nose Throat J. 2021 Apr 8:1455613211009441. doi: 10.1177/01455613211009441. Online ahead of print. ABSTRACT INTRODUCTION: Extirpation of multiple head and neck paragangliomas carries challenge due to close anatomic relationships with critical neurovascular bundles. OBJECTIVES: This study aims to assess whether the application of 3-D models can assist with surgical planning and treatment of these paragangliomas, decrease surgically related morbidity and mortality. METHODS: Fourteen patients undergoing surgical resection of multiple head and neck paragangliomas were enrolled in this study. A preoperative 3-D model was created based on radiologic data, and relevant critical anatomic relationships were preoperatively assessed and intraoperatively validated. RESULTS: All 14 patients presented with multiple head and neck paragangliomas, including bilateral carotid body tumors (CBT, n = 9), concurrent CBT with glomus jugulare tumors (GJT, n = 4), and multiple vagal paragangliomas (n = 1). Ten patients underwent genomic analysis and all harbored succinate dehydrogenase complex subunit D (SDHD) mutations. Under guidance of the 3-D model, the internal carotid artery (ICA) was circumferentially encased by tumor on 5 of the operated sides, in 4 (80%) of which the tumor was successfully dissected out from the ICA, whereas ICA reconstruction was required on one side (20%). Following removal of CBT, anterior rerouting of the facial nerve was avo ided in 3 (75%) of 4 patients during the extirpation of GJT with assistance of a 3-D model. Two patients developed permanent postoperative vocal cord paralysis. There was no vessel rupture or mortality in this study cohort. CONCLUSION: The 3-D model is beneficial for establishment of a preoperative strategy, as well as planning and guiding the intraoperative procedure for resection of multiple head and neck paragangliomas. PMID:33829883 | DOI:10.1177/01455613211009441 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Nasal Septum Glomus Tumor: A Rare Cause of Unilateral Nasal Obstruction

xlomafota13 shared this article with you from Inoreader Nasal Septum Glomus Tumor: A Rare Cause of Unilateral Nasal Obstruction Via ear nose throat Ear Nose Throat J. 2021 Apr 8:1455613211007948. doi: 10.1177/01455613211007948. Online ahead of print. NO ABSTRACT PMID:33829885 | DOI:10.1177/01455613211007948 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.