Profiling Long Noncoding RNA Expression Using Custom-Designed Microarray.

Profiling Long Noncoding RNA Expression Using Custom-Designed Microarray.

Methods Mol Biol. 2016;1402:33-41

Authors: Zhang X, Lopez-Berestein G, Sood AK, Calin GA

Abstract
Long noncoding RNAs (lncRNAs) are an important class of pervasive genes involved in a variety of biological functions. The abnormal expression of lncRNAs has been implicated in a range of many human diseases, including cancer. But only a small number of functional lncRNAs have been well characterized to date. lncRNA expression profiling may help to identify useful molecular biomarkers and targets for novel therapeutic approaches in the future. In this chapter, we describe a highly efficient lncRNA expression profiling method using a custom-designed microarray.

PMID: 26721482 [PubMed - in process]

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