Background: Complex periorbital subunit reconstruction is challenging because the goals of effective reconstruction vary from one individual to another. The purpose of this article is to explore the indications and anatomic feasibility of periorbital transplantation by reviewing our institutional repository of facial injury. Methods: Institutional review board approval was obtained at the R Adams Cowley Shock Trauma Center for a retrospective chart review conducted on patients with periorbital defects. Patient history, facial defects, visual acuity, and periorbital function were critically reviewed to identify indications for periorbital or total face (incorporating the periorbital subunit) vascularized composite allotransplantation. Cadaveric allograft harvest was then designed and performed for specific patient defects to determine anatomic feasibility. Disease conditions not captured by our patient population warranting consideration were reviewed. Results: A total of 7 facial or periorbital transplant candidates representing 6 different etiologies were selected as suitable indications for periorbital transplantation. Etiologies included trauma, burn, animal attack, and tumor, whereas proposed transplants included isolated periorbital and total face transplants. Allograft recovery was successfully completed in 4 periorbital subunits and 1 full face. Dual vascular supply was achieved in 5 of 6 periorbital subunits (superficial temporal and facial vessels). Conclusions: Transplantation of isolated periorbital structures or full face transplantation including periorbital structures is technically feasible. The goal of periorbital transplantation is to re-establish protective mechanisms of the eye, to prevent deterioration of visual acuity, and to optimize aesthetic outcomes. Criteria necessary for candidate selection and allograft design are identified by periorbital defect, periorbital function, ophthalmologic evaluation, and defect etiology.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- The metabolic vascular syndrome – guide to an indi...
- SC: Any proof that smoking causes cancer? – Times ...
- When does chronic migraine strike? A clinical comp...
- IJERPH, Vol. 13, Pages 302: Meta-Analysis of Cardi...
- Nanomaterials, Vol. 6, Pages 46: Formation and Con...
- Mitteilungen der GfH
- Modified Hotz Procedure Combined with Modified Z-E...
- Usability Evaluation of a Clinical Decision Suppor...
- A Simple New Technique for Treatment of Tarsal Kin...
- Designs for Evaluating the Community-Level Impact ...
- Translating Inhibitory Fc Receptor Biology into No...
- Aging of perennial cells and organ parts according...
- Stromal β-catenin overexpression contributes to th...
- Multiple myeloma exosomes establish a favorable bo...
- Toll-like receptor signalling in regenerative myog...
- Altered ratios of pro- and anti-angiogenic VEGF-A ...
- Catalog of genetic progression of human cancers: n...
- When does chronic migraine strike? A clinical comp...
- SC: Any proof that smoking causes cancer? – Times ...
- IJERPH, Vol. 13, Pages 302: Meta-Analysis of Cardi...
- Optimizing Reconstruction with Periorbital Transpl...
- Reconstruction of an Entire Thumb Metacarpal: A Ca...
- Predicting Cellular Rejection With a Cell-Based As...
- Outcomes From Pancreatic Transplantation in Donati...
- Long-term Follow-up of Kidney Transplant Recipient...
- Biomarkers of Transplant Tolerance: A Provisional ...
- Liver microRNA Profile of Induced Allograft Tolera...
- Midodrine Dependence: Transplantation Barrier or O...
- Pretransplant Midodrine Use: A Newly Identified Ri...
- Optimizing Reconstruction with Periorbital Transpl...
- Reconstruction of an Entire Thumb Metacarpal: A Ca...
- Predicting Cellular Rejection With a Cell-Based As...
- Outcomes From Pancreatic Transplantation in Donati...
- Long-term Follow-up of Kidney Transplant Recipient...
- Biomarkers of Transplant Tolerance: A Provisional ...
- Liver microRNA Profile of Induced Allograft Tolera...
- Midodrine Dependence: Transplantation Barrier or O...
- Pretransplant Midodrine Use: A Newly Identified Ri...
- Burden of disease and patient-reported outcomes in...
- Solid-type primary intraosseous squamous-cell carc...
- A Unique Ocular Presentation of Extragenital Liche...
- IJMS, Vol. 17, Pages 349: MicroRNAs in Osteoclasto...
- Modified Hotz Procedure Combined with Modified Z-E...
- A Survey on Hong Kong Secondary School Students’ K...
- Diagnostic Radiation Exposure of Injury Patients i...
- Optimizing indomethacin-loaded chitosan nanopartic...
- Variations in Concentration and Distribution of Se...
- Effectiveness of Educational Poster on Knowledge o...
- Antioxidant activity of Inonotus obliquus polysacc...
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