Huntington disease (HD) has a protracted course that imparts substantial personal and economic burden.1 Disease rates vary by geographic location. In Western countries, prevalence approximates 5.7/100,000; rates are tenfold lower in Asia.2 Epidemiologic studies from the United States report on mostly white populations.2 Few studies give rates of HD among minorities, and there are no comprehensive descriptions of HD in American Indians. Better understanding of how the disease affects discrete populations could produce hypotheses for new approaches to treatment.
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