Σφακιανάκης Αλέξανδρος
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Δευτέρα 13 Ιουνίου 2016

Adenocarcinoma of the Lung Metastasizing to the Mandible


Publication date: Available online 12 June 2016
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Sibel Elif Gultekin, Burcu Senguven, Ipek Isik Gonul, Begum Okur, Reinhard Buettner
Lung cancer is the most frequent cause of cancer-related death worldwide. Metastases of non-small cell lung carcinoma to the oral and maxillofacial region are rare. Thus, the diagnosis of a metastatic lesion in the oral cavity is challenging, both to the clinician and to the pathologist. We present a case of a 72-year-old male patient with metastatic lung adenocarcinoma located in the posterior mandibular region. Next-generation sequencing analysis revealed no significant mutations in the relevant genes except in the TP53 tumor suppressor gene.


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