Ειδοποίηση Μελετητή:[ Melanoma ]
CD271 downregulation promotes melanoma progression and invasion in 3-dimensional models and in zebrafish
A Saltari, F Truzzi, M Quadri, R Lotti, E Palazzo… - Journal of Investigative …, 2016
Abstract CD271 is a neurotrophin receptor variably expressed in melanoma. While
contradictory data are reported on its role as a marker of tumor initiating cells, little is known
on its function in tumor progression. CD271 expression was higher in spheroids derived ...
contradictory data are reported on its role as a marker of tumor initiating cells, little is known
on its function in tumor progression. CD271 expression was higher in spheroids derived ...
Extensive surgery and lymphadenectomy do not improve survival in primary melanoma of the anorectum: results from analysis of a large database (SEER)
A Ciarrocchi, R Pietroletti, F Carlei, G Amicucci - Colorectal Disease, 2016
Aim Primary anorectal melanoma is a rare disease with a dismal prognosis due to early
distant metastasis. The prognostic value of positive loco-regional lymph nodes and the
impact of lymphadenectomy on overall survival is unclear. We have investigated this by ...
distant metastasis. The prognostic value of positive loco-regional lymph nodes and the
impact of lymphadenectomy on overall survival is unclear. We have investigated this by ...
Promoter structures and differential responses to viral and non-viral inducers of chicken melanoma differentiation-associated gene 5
WX Zhang, EW Zuo, Y He, DY Chen, X Long, MJ Chen… - Molecular Immunology, 2016
Abstract Melanoma differentiation-associated gene 5 (MDA5) is a member of the retinoic
acid-inducible gene I (RIG-I)-like receptors (RLRs) family and plays a pivotal role in the anti-
viral innate immune response. As RIG-I is absent in chickens, MDA5 is hypothesized to be ...
acid-inducible gene I (RIG-I)-like receptors (RLRs) family and plays a pivotal role in the anti-
viral innate immune response. As RIG-I is absent in chickens, MDA5 is hypothesized to be ...
The role of aberrant AKT activation in melanoma growth and metastasis
JH Cho - 2016
Abstract: Melanoma is the most deadly skin malignancy and one of the most rapidly
increasing cancers. Like other cancers, melanoma is known to exploit specific signaling
pathways for growth and disease progression. The AKT pathway is aberrantly activated in ...
increasing cancers. Like other cancers, melanoma is known to exploit specific signaling
pathways for growth and disease progression. The AKT pathway is aberrantly activated in ...
Malignant Melanoma of the Syrinx and Liver in an African Grey Parrot (Psittacus erithacus erithacus)
TC Shrader, JW Carpenter, AG Cino-Ozuna… - Journal of Avian Medicine …, 2016
Abstract A 20-year-old, female African grey parrot (Psittacus erithacus erithacus) was
examined because of ataxia and weakness. Radiographs were unremarkable, and results of
a complete blood cell count revealed leukocytosis and heterophilia. Because of poor ...
examined because of ataxia and weakness. Radiographs were unremarkable, and results of
a complete blood cell count revealed leukocytosis and heterophilia. Because of poor ...
Collagenous colitis (First report) complicated by hypokalaemia and weight loss: case report
B Baroudjian - Reactions, 2016
... The woman with the diagnosis of left maxillary sinus melanoma was started on pembrolizumab
2 mg/kg infusion every 3 weeks, in August 2014. ... Reference. Baroudjian B, et al. Anti-PD1-induced
collagenous colitis in a melanoma patient. Melanoma Research 26: 308-311, No. ...
2 mg/kg infusion every 3 weeks, in August 2014. ... Reference. Baroudjian B, et al. Anti-PD1-induced
collagenous colitis in a melanoma patient. Melanoma Research 26: 308-311, No. ...
Dermatologic Manifestations of the Lower Extemity, an Issue of Clinics in Podiatric Medicine and Surgery
TC Vlahovic - 2016
... 355 367 385 397 Page 10. Contents ix Melanoma of the Foot Ivan Bristow and Chris Bower
Melanoma is a rare form of skin cancer that is responsible for most skin cancer deaths globally.
Tumors arising on the foot continue to be a particular challenge. ...
Melanoma is a rare form of skin cancer that is responsible for most skin cancer deaths globally.
Tumors arising on the foot continue to be a particular challenge. ...
Computer Assisted Diagnosis of Basal Cell Carcinoma Using Z-transform Features
N Noroozi, A Zakerolhosseini - Journal of Visual Communication and Image …, 2016
... Basal cell carcinoma (BCC) is the most common form of skin cancer and accounts for
approximately 70% of non-melanoma skin cancers [1] and [2]. This epithelial malignant tumor
consists of cells which look like the basal layer of the epidermis with a rather chaotic arrangement ...
approximately 70% of non-melanoma skin cancers [1] and [2]. This epithelial malignant tumor
consists of cells which look like the basal layer of the epidermis with a rather chaotic arrangement ...
Ipilimumab/nivolumab/vemurafenib
FC Fierz - Reactions, 2016
... requires intervention to prevent permanent impairment or damage. Three men, aged 43−57 years,
were described who developed uveitis during treatment with ipilimumab, nivolumab and/or
vemurafenib [routes and dosages not stated] for cutaneous Melanoma. ...
were described who developed uveitis during treatment with ipilimumab, nivolumab and/or
vemurafenib [routes and dosages not stated] for cutaneous Melanoma. ...
[HTML] Localized Field External Beam Radiation Therapy after Metastasectomy of Solitary Brain Lesion
AA El-Aziz Ghannam, RA El-Ghany Khedr, MF Ibrahim… - Neuro-Oncology: Open …, 2016
... of these diseases. However, melanoma is the third in frequency to metastasize to
brain irrespective to its low incidence [1]. This selectivity may be attributed to the
special microenvironment of the brain [3]. Patients with single ...
brain irrespective to its low incidence [1]. This selectivity may be attributed to the
special microenvironment of the brain [3]. Patients with single ...
Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated …
M Kostine, AHG Cleven, NFCC de Miranda, A Italiano… - Modern Pathology, 2016
... of ipilimumab, an anticytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) antibody, followed
by nivolumab and pembrolizumab, two anti-programmed death 1 (anti-PD-1) antibodies,
represented a considerable progress in the treatment of metastatic melanoma and non-small ...
by nivolumab and pembrolizumab, two anti-programmed death 1 (anti-PD-1) antibodies,
represented a considerable progress in the treatment of metastatic melanoma and non-small ...
Acne inversa-like skin lesions: case report
A Thiem - Reactions, 2016
... A 50-year-old woman developed acne inversa-like skin lesions following vemurafenib therapy.
The woman, who was diagnosed with stage IV BRAF V600E-mutated melanoma, started
receiving vemurafenib at a dose of 960mg twice daily [route not stated]. ...
The woman, who was diagnosed with stage IV BRAF V600E-mutated melanoma, started
receiving vemurafenib at a dose of 960mg twice daily [route not stated]. ...
Integumentary Disorders Including Cutaneous Neoplasia in Older Horses
DC Knottenbelt - Veterinary Clinics of North America: Equine Practice, 2016
... Primary neoplastic disorders of the skin of older horses. Melanoma. Summary. Melanoma is a
tumor that arises from naturally occurring melanocytes, which are the pigment-producing cells
in the skin and other parts of the body. ... Anaplastic Malignant Melanoma. Summary. ...
tumor that arises from naturally occurring melanocytes, which are the pigment-producing cells
in the skin and other parts of the body. ... Anaplastic Malignant Melanoma. Summary. ...
Recollections from a Pioneer Who Provided the Foundation for the Success of Gene Therapy in Treating Severe Combined Immune Deficiencies
JM Wilson - Human Gene Therapy Clinical Development, 2016
... Mike was now also in the NCI working with another of my colleagues two floors below my lab,
Steve Rosenberg. Steve's group was using lymphocytes as therapeutic weapons in cancer
immunotherapy and had worked on ways of growing lymphocytes from melanoma tumors. ...
Steve Rosenberg. Steve's group was using lymphocytes as therapeutic weapons in cancer
immunotherapy and had worked on ways of growing lymphocytes from melanoma tumors. ...
Primary Care of Adult Women
CD Conditions - Primary Care of Adult Women, an Issue of Obstetrics …, 2016
... 29 MELANOMA Epidemiology Melanoma is a malignant tumor that arises from
melanocytes and is most commonly of cutaneous origin, but can also arise from the
oral, conjunctival, and vagina mucosa. The lifetime risk of melanoma ...
melanocytes and is most commonly of cutaneous origin, but can also arise from the
oral, conjunctival, and vagina mucosa. The lifetime risk of melanoma ...
Intratumoral expression of programmed death ligand 1 (PD-L1) in patients with clear cell renal cell carcinoma (ccRCC)
M Abbas, S Steffens, M Bellut, H Eggers, A Großhennig… - Medical Oncology, 2016
... Legend: CI, confidence interval. Discussion. Clinical phase I trials with anti-PD1/PD-L1 agents
showed durable objective responses in refractory melanoma and RCC patients [22]. ... Safety and
tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. ...
showed durable objective responses in refractory melanoma and RCC patients [22]. ... Safety and
tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. ...
A comparison of functional fragrant components of Cymbidium (oriental orchid) species.
K SungMin, J EuJean, H JongWon, S SungHo… - Korean Journal of …, 2016
... cells (HepG2), inhibits the growth of Streptococcus mutans and babesiosis, and has antibacterial
properties, are common substances produced by C. goeringii L. Nerolidol and β-bisabolene,
which is cytotoxic and suppresses the growth of malignant melanoma cells (B16-F10 ...
properties, are common substances produced by C. goeringii L. Nerolidol and β-bisabolene,
which is cytotoxic and suppresses the growth of malignant melanoma cells (B16-F10 ...
Sarcoid-like syndrome: case report
K Meinhof - Reactions, 2016
... A 59-year-old man developed sarcoid-like syndrome following treatment with ipilimumab.
The man received 4 cycles of combination treatment with ipilimumab [dosage and route
not stated] and talimogene laherparepvec for metastatic melanoma. ...
The man received 4 cycles of combination treatment with ipilimumab [dosage and route
not stated] and talimogene laherparepvec for metastatic melanoma. ...
Adjuvant Combinations of NKT Activator, CD40 Agent, CD40 Agonist, and Optional Antigen, the Use Through Inducing Synergistic Cellular Immunity
C Ahonen, R Noelle - US Patent 20,160,158,348, 2016
... FIG. 3 contains an experiment in mice immunized with melanoma cells showing that
CD40/TLR* vaccination therapeutically intervenes in systemic melanoma. FIG. ... 2). Example
3. CD40/TLR* Vaccination Therapeutically Intervenes in Systemic Melanoma. ...
CD40/TLR* vaccination therapeutically intervenes in systemic melanoma. FIG. ... 2). Example
3. CD40/TLR* Vaccination Therapeutically Intervenes in Systemic Melanoma. ...
Primary Care of Adult Women, an Issue of Obstetrics and Gynecology Clinics of North America
JN Woodruff, AK Blanchard - 2016
... treatment of common skin conditions. This article provides an overview of acne,
rosacea, melasma, vitiligo, alopecia, non- melanoma and melanoma skin cancer,
dermatitis, and lichen sclerosus. Clinical Management of Obesity ...
rosacea, melasma, vitiligo, alopecia, non- melanoma and melanoma skin cancer,
dermatitis, and lichen sclerosus. Clinical Management of Obesity ...
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