Abstract
Squamous cell carcinoma of the head and neck region (HNSCC) including oral cavity, oropharynx, larynx and hypopharynx is the 6th most common cancer in the world. In 2012, 690.000 new cases of head neck cancer were diagnosed worldwide thus accounting for 4.9% of all malignant tumors (Braakhuis et al., 2014). Recent estimates showed 100.000 new cases of cancer of the oral cavity and the pharynx in Europe every year (Ferlay et al., 2013).
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