Closure of Skin Incision by Dual Wavelength (980&1064 nm) Laser Application.
J Cosmet Laser Ther. 2016 Oct 24;:1-13
Authors: Uba AI, Tabakoglu HO, Abdullahi UA, Sani MM
Abstract
Thermal effect of dual wavelength (980 & 1064nm) laser application in skin incision closure was assessed on 18 male and female Wister rats. 1cm-long Incisions were made on the shaved dorsal region of 220-250g animals. The incisions were closed by laser irradiation at 1W and exposure time, 5 seconds in Continuous wave mode (CW) and 1W and exposure time, 10 seconds in pulsed mode to deliver a total energies, 5J and 10J per spot onto the incisions respectively. Animals from each group were sacrificed at 0th, 4th and 7th days and the skin samples of the weld area were excised for histological analysis using H&E Stain. Mean thermally altered area (TAA) of CW mode laser treated groups was found to increase significantly (p<0.05) compared with pulsed mode laser treated group at 0(th) and 4(th) days post-irradiation while no significant difference (p>0.05) was statistically found at 7th day post-irradiation. Moreover, tighter closure was observed with CW group at 7th day post-irradiation. We thus conclude that 1W, 5J for 5 seconds CW mode laser application of 980 & 1064nm combined beam form in skin incision closure was found to have absolute wound healing capability with minimal thermal alteration.
PMID: 27775451 [PubMed - as supplied by publisher]
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