Immune modules shared by innate lymphoid cells and T cells

Publication date: November 2016
Source:Journal of Allergy and Clinical Immunology, Volume 138, Issue 5
Author(s): Michelle L. Robinette, Marco Colonna
In recent years, innate lymphoid cells (ILCs) have emerged as innate correlates to T cells. The similarities between ILCs and T cells indicate that lymphocytes of fundamentally distinct lineages can share core "immune modules" that encompass transcriptional circuitry and effector functions while using nonredundant complementary mechanisms of pattern recognition to enact these functions. We review modules currently recognized to be shared between ILCs and T cells.



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