Quality of life changes following concurrent septoplasty and/or inferior turbinoplasty during endoscopic pituitary surgery.

Quality of life changes following concurrent septoplasty and/or inferior turbinoplasty during endoscopic pituitary surgery.

World Neurosurg. 2016 Nov 9;:

Authors: Lee DD, Peris-Celda M, Butrymowicz A, Kenning T, Pinheiro-Neto CD

Abstract
OBJECTIVES/ HYPOTHESIS: Endoscopic endonasal transsphenoidal surgery (EETS) is a widely accepted technique for sellar tumors. Common findings during pre-operative assessment include septal deviations and turbinate hypertrophy. This study aims to evaluate quality of life changes following a concurrent septoplasty and/or inferior turbinoplasty during EETS.
STUDY DESIGN: A retrospective review of a prospectively collected database including all patients receiving ETTS at our institution from 2014-2016.
METHODS: Patients were divided into a septoplasty / inferior turbinoplasty group (SIG) and a no septoplasty / inferior turbinoplasty group (NSIG). Quality of life outcome measures were evaluated using the Sino-Nasal Outcome Test (SNOT-22). Mean pre-operative scores were compared to 1 and 3 month post-operative scores within each cohort. The SNOT-22 was also reorganized into five distinct subdomains. Average subdomain scores were calculated and preoperative, 1 and 3 month subdomain scores were compared within each cohort. A paired t-student test was utilized. P values were considered statistically significant if they measured less than 0.05.
RESULTS: All 24 patients met inclusion criteria by completing pre and post-operative SNOT-22 surveys. In the SIG, pre-operative and 3 month post-operative scores showed a clinically significant difference (p=0.047). The SIG specifically showed a significant difference in the psychiatric and sleep SNOT-22 subdomains when comparing pre-operative to 3 month post-operative scores (p=0.03, p=0.01).
CONCLUSION: Patients who underwent a concurrent septoplasty and/or turbinoplasty in association with EETS had a significantly improved quality of life compared to preoperative assessment, specifically with psychological and sleep symptoms.

PMID: 27838428 [PubMed - as supplied by publisher]

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