Cardiovascular pre-clinical imaging.

Cardiovascular pre-clinical imaging.

Q J Nucl Med Mol Imaging. 2016 Dec 16;

Authors: Nekolla SG, Rischpler C, Paschali A, Anagnostopoulos C

Abstract
Non-invasive imaging in the form of SPECT, PET, CT, echocardiography or MRI is a very useful tool for cardiovascular research as it allows assessment of biological processes in vivo. Nuclear imaging with SPECT and PET offers the advantage of high sensitivity, the potential for serial imaging, and reliable quantification. Currently a wide range of established as well as innovative agents is available and can be imaged with dedicated preclinical and clinical SPECT and PET imaging systems. These scanners can be equipped with CT and MRI components to form hybrid imaging systems. This review provides an outline on SPECT and PET as capable tools for translational research in cardiology as part of a "workflow" similar to the one used in clinical imaging illustrating the concept from "bench to bedside".

PMID: 27982544 [PubMed - as supplied by publisher]

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