Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

Publication date: Available online 8 December 2016
Source:Data in Brief
Author(s): Christian Meinert, Franziska Kohse, Ilka Böhme, Florian Gembardt, Anja Tetzner, Thomas Wieland, Barry Greenberg, Thomas Walther
In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1h, 3h, 6h, and 9h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.



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