Primary cutaneous CD30+ anaplastic large cell lymphoma treated with radiotherapy and methotrexate with development of xanthomas at the sites of prior disease.

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Primary cutaneous CD30+ anaplastic large cell lymphoma treated with radiotherapy and methotrexate with development of xanthomas at the sites of prior disease.

J Cutan Pathol. 2016 Apr;43(4):400-5

Authors: Turrión-Merino L, Perez-Gala S, Hermosa-Zarza E, Urech-García-de-la-Vega M, Carrillo-Guijón R, Jaén-Olasolo P

Abstract
Primary cutaneous anaplastic large cell lymphoma is a rare type of cutaneous T-cell lymphoma, and the involvement of the ocular adnexa is extremely rare. Secondary xanthoma-like changes after radiation therapy or chemotherapy have been rarely reported in association with large-cell T-cell anaplastic lymphoma. We report one case of a primary C-anaplastic large cell lymphoma affecting the eyelid with fast progression with multiple nodules in various anatomic sites and development of xanthoma-like lesions after treatment.

PMID: 26695345 [PubMed - indexed for MEDLINE]

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