Cardiac Shear Wave Velocity Detection in the Porcine Heart

Publication date: Available online 5 January 2017
Source:Ultrasound in Medicine & Biology
Author(s): Hendrik J. Vos, Bas M. van Dalen, Ilkka Heinonen, Johan G. Bosch, Oana Sorop, Dirk J. Duncker, Antonius F.W. van der Steen, Nico de Jong
Cardiac muscle stiffness can potentially be estimated non-invasively with shear wave elastography. Shear waves are present on the septal wall after mitral and aortic valve closure, thus providing an opportunity to assess stiffness in early systole and early diastole. We report on the shear wave recordings of 22 minipigs with high-frame-rate echocardiography. The waves were captured with 4000 frames/s using a programmable commercial ultrasound machine. The wave pattern was extracted from the data through a local tissue velocity estimator based on one-lag autocorrelation. The wave propagation velocity was determined with a normalized Radon transform, resulting in median wave propagation velocities of 2.2 m/s after mitral valve closure and 4.2 m/s after aortic valve closure. Overall the velocities ranged between 0.8 and 6.3 m/s in a 95% confidence interval. By dispersion analysis we found that the propagation velocity only mildly increased with shear wave frequency.



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