Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids

Publication date: 5 January 2017
Source:Cell Stem Cell, Volume 20, Issue 1
Author(s): Christopher R. Schlieve, Tracy C. Grikscheit
The enteric nervous system (ENS) regulates numerous gastrointestinal functions, including epithelial barrier permeability and motility. In a recent Nature Medicine study, Workman et al. (2016) propose a method for introducing human pluripotent stem cell-derived enteric neural crest cells into developing human intestinal organoids, thereby restoring ENS cell types and contractile function.

Teaser

The enteric nervous system (ENS) regulates numerous gastrointestinal functions, including epithelial barrier permeability and motility. In a recent Nature Medicine study, Workman et al. (2016) propose a method for introducing human pluripotent stem cell-derived enteric neural crest cells into developing human intestinal organoids, thereby restoring ENS cell types and contractile function.


http://ift.tt/2iOOZmu