Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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! # Ola via Alexandros G.Sfakianakis on Inoreader

Η λίστα ιστολογίων μου

Τετάρτη 8 Μαρτίου 2017

A European subset analysis from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) shows country-specific features: Results from psoriasis patients in Spain

Abstract

Background

The Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) survey data were not analysed to account for cultural and healthcare system differences across European countries (EC).

Objective

Utilize MAPP data to characterize psoriasis in Spanish patients, including severity assessment and Dermatology Life Quality Index (DLQI).

Methods

MAPP was conducted between June and August 2012. This analysis included 1700 patients with self-reported psoriasis (without psoriatic arthritis) from France (n=349), Germany (n=311), Italy (n=359), Spain (n=354) and the United Kingdom (n=327).

Results

Patients from Spain versus other EC self-reported higher mean body mass index (26.9 vs. 25.6, P≤0.001), lower prevalence of depression (6% vs. 12%, P=0.002) and higher mean self-perceived psoriasis severity at its worst (5.92 vs. 5.33, P<0.001) despite lower estimated body-surface-area involvement. Overall, patients from Spain versus other EC had lower mean global DLQI scores (4.70 vs. 6.06, P=0.001) and mean scores for each DLQI dimension (all P<0.001, except leisure [P=0.002], treatment [P=0.002], and work and school [P=0.005]). Higher DLQI values were inversely associated with age and directly correlated with perceived severity. Palmoplantar, nail and scalp psoriasis were reported less frequently in Spanish patients (P≤0.026) and were associated with higher DLQI values (P<0.01). Spanish patients were more likely to have seen multiple healthcare providers (HCPs, P<0.001) and achieve therapeutic goals (P<0.001), but current treatments were similar to patients in other EC.

Conclusions

In the MAPP survey, Spanish patients differed from other EC in several characteristics, including comorbidities, extent and distribution of psoriasis lesions, perception of severity and impact on quality-of-life. Their perception of psoriasis severity was higher despite a lower estimated extent, and DLQI scores were significantly lower. Spanish patients had more HCP visits and a higher rate of therapeutic goal achievement. These differences might be attributed to cultural factors, phenotypical variation and differences in HCP access.

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