Abstarct
Clinical outcomes for patients with oral squamous cell carcinoma are, in large part, related to the tumor stage at diagnosis (Warnakulasuriya, 2009). In particular, loco-regional spread is a key predictor of poor prognosis. Knowledge of the molecular events that contribute to oral tumorigenesis is considerable (Agrawal et al., 2011, Hunter et al., 2005, Leemans et al., 2011, Stransky et al., 2011); yet, the processes that contribute to metastasis of primary oral tumor cells are poorly understood.
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