Colonic Schwannoma: A Case Study and Literature Review of a Rare Entity and Diagnostic Dilemma.

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Colonic Schwannoma: A Case Study and Literature Review of a Rare Entity and Diagnostic Dilemma.

Am Surg. 2016 Dec 01;82(12):1183-1186

Authors: Uhr A, Singh AP, Munoz J, Aka A, Sion M, Jiang W, Goldstein SD, Rosato EL

Abstract
An asymptomatic 73-year-old woman was found to have a submucosal mass in the descending colon on routine colonoscopy. A CT scan revealed a 31 × 28 × 31 mm lesion in the same location. Previous biopsy proved to be nondiagnostic, and the patient underwent a laparoscopic descending colon resection. Histologic evaluation of the tumor revealed a low grade spindle cell neoplasm with strong, diffuse positivity for S-100 protein by immunohistochemistry, leading to the diagnosis of schwannoma. A review of the literature revealed intestinal schwannoma to be a rare disease entity, with only about 50 cases previously reported.

PMID: 28234182 [PubMed - indexed for MEDLINE]

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