Publication date: Available online 9 March 2017
Source:Revista Española de Medicina Nuclear e Imagen Molecular
Author(s): B. González García, A.M. García Vicente, G.A. Jiménez Londoño, F.J. Pena Pardo, M.E. Bellón Guardia, M.P. Talavera Rubio, A. Palomar Muñoz, P. Gómez Herrero, Á.M. Soriano Castrejón
ObjetivoInvestigar la relación del valor máximo estandarizado de captación (SUVmáx) de la lesión ovárica con el subtipo histopatológico (I/II) y su implicación en la respuesta al tratamiento y en el pronóstico de las pacientes con carcinoma epitelial de ovario (CEO).Material y métodosAnálisis retrospectivo de 31 pacientes con CEO y 18F-FDG-PET/TC previo al tratamiento, determinándose el SUVmáx de la lesión ovárica y realizándose diagnóstico histopatológico del tumor y seguimiento clínico-radiológico.Se estudió la relación del SUVmáx con el tipo histológico (tipos I y II) y el estadio tumoral, así como la implicación de este y otros parámetros (histología, estadio) en la evolución de las pacientes (respuesta completa [RC], supervivencia global [SG], supervivencia libre de enfermedad [SLE], estado libre de enfermedad a los 12 meses [LE12m] y a los 24 meses [LE24m]).ResultadosEl SUVmáx medio en lesiones tipo I fue menor que en las tipo II (6,3 y 9,3, respectivamente; p=0,03). Se obtuvo un valor de corte de SUVmáx de 7,1 en la identificación del CEO tipo II (sensibilidad: 77,8%; especificidad: 69,2%; AUC=0,748; p=0,02). No se halló relación significativa entre SUVmáx y estadio tumoral.Alcanzar RC fue más frecuente en estadios precoces; riesgo relativo (RR) de 1,64; p=0,003, en tumores tipo I y en los de menor SUVmáx.El estadio tumoral fue determinante en la SLE (p=0,04), en el LE24m (p=0,07) y en la SG (p=0,08). Observamos SLE más prolongadas y mayor porcentaje de pacientes LE24m en tumores tipo I (RR: 1,32; p=0,26).ConclusionesEl SUVmáx se relacionó con el tipo histológico del CEO. No se encontró relación entre la actividad glucolítica del tumor primario con la respuesta y el pronóstico.ObjectiveTo investigate the relationship between maximum standardised uptake value (SUVmax) of ovarian lesions and histopathology subtypes, and their involvement in the response and prognosis of patients with epithelial ovarian carcinoma (EOC).Material and methodsA retrospective analysis of 31 patients with EOC and 18F-FDG-PET/CT before treatment, including an assessment of the SUVmax of ovarian lesion. Histopathological diagnosis and follow-up was performed.A study was made on the relationship between the SUVmax and histological type (type I and II) and tumour stage, as well as the role of various parameters (SUVmax, histology, stage) on the patient outcomes (complete response [CR], overall survival [OS], disease-free survival [DFS], and disease-free [DF] status, at 12 and 24 months).ResultsThe medium SUVmax in type I lesions was lower than in type II (6.3 and 9.3, respectively; P=.03). A 7.1 cut-off was set for SUVmax in order to identify type II EOC (sensitivity: 77.8%, specificity: 69.2%; AUC=0.748; P=.02). No significant relationship was found between tumour stage and SUVmax.CR was more common in early stages; relative risk (RR) of 1.64; P=.003, as well as in type I tumours and a lower SUVmax.Tumour stage was decisive in DFS (P=.04), LE24m (0.07) and OS (P=.08). Longer DFS and a higher percentage of DF 24m were observed in type I tumours (RR: 1.32; P=.26).ConclusionsSUVmax was related to EOC histology, so could predict the response and prognosis of these patients. No association was found between glycolytic activity of the primary tumor with the response and prognosis.
http://ift.tt/2mLlt2Y
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
►
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
▼
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
-
▼
Μαρτίου
(11966)
-
▼
Μαρ 09
(457)
- Voice outcomes for early laryngeal cancer.
- Social and quality of life impact using a voice pr...
- Dysphagia management in tracheostomized patients: ...
- Voice and swallowing outcomes for adults undergoin...
- The use of practice guidelines in the management o...
- Self-reported postoperative recovery in children a...
- Foreign body aspiration in children: Focus on the ...
- Anti-angiogenic treatment for breast cancer?
- The role of drug-drug interactions in prostate can...
- Incidental Findings on Pediatric Abdominal Magneti...
- Dosimetric Analysis of Liver Toxicity Post Liver M...
- Outcomes and Toxicity following High-Dose Radiatio...
- Persistent nasal carriers of Acinetobacter baumann...
- A New Keystone Flap “Plus” Design: Case Series and...
- Failure to Diagnose an Incompetent Cervix,Prematur...
- Permanent prostate brachytherapy pubic arch evalua...
- Assessment of clinical and radiologic differences ...
- Use of hepatobiliary phase images in Gd-EOB-DTPA-e...
- Unusual ultrasound appearance of small bowel intus...
- Contrast-enhanced ultrasound and computed tomograp...
- Neocortical and hippocampal TREM2 protein levels d...
- Engineering intravaginal vaccines to overcome muco...
- Islet encapsulation with polyphenol coatings decre...
- Tolerability, usability and acceptability of disso...
- TANTIGEN: a comprehensive database of tumor T cell...
- Murine Th17 cells utilize IL-2 receptor gamma chai...
- Acoustic Context Alters Vowel Categorization in Pe...
- Verrucarin A and roridin E produced on spinach by ...
- Withdrawing ASV therapy in clinical practice: tria...
- Risk of developing obstructive sleep apnea among w...
- Natural course and potential prognostic factors fo...
- The Transient Receptor Potential Melastatin 7 Chan...
- Reactivating p53 and Inducing Tumor Apoptosis (RIT...
- Noninvasive Bioluminescence Imaging of AKT Kinase ...
- Emergency cricothyrotomy: temporary measure or def...
- Foreign body aspiration in children: Focus on the ...
- Close surgical margin after conservative parotidec...
- Our auditory results using the Vibrant Soundbridge...
- The clinical manifestations of vestibular migraine...
- Comparing performance of Fastrach ILMA vs flexible...
- Targeting BMI1+ Cancer Stem Cells Overcomes Chemor...
- PRC2 Facilitates the Regulatory Topology Required ...
- Mex3a Marks a Slowly Dividing Subpopulation of Lgr...
- New in vivo model to analyse the expression of ang...
- Stimuli-responsive shell cross-linked micelles fro...
- Novel endodontic sealers induce cell cytotoxicity ...
- Root canal morphology and variations in mandibular...
- Lipid parameters in obese and normal weight patien...
- Odontogenic differentiation potential of human den...
- Integrative Proteomics and Phosphoproteomics Profi...
- Concentration-dependent alterations in gene expres...
- Iron-based adsorbent prepared from Litchi peel bio...
- Amelioration of boron toxicity in sweet pepper as ...
- Effect of foliar application of plant growth regul...
- Withered on the stem: is bamboo a seasonally limit...
- Frequencies of erythrocyte nuclear abnormalities a...
- Using early life stages of marine animals to scree...
- Toxic effect of nonylphenol on the marine macroalg...
- Unique characteristics of algal dissolved organic ...
- Precipitation and air temperature control the vari...
- The death of the circulatory system diseases in Ch...
- Slow-release formulations of the herbicide piclora...
- Migration of nitrate, nitrite, and ammonia through...
- Investigations of temperature and pH variations on...
- Enhancing filterability of activated sludge from l...
- Enhanced heterogeneous photo-Fenton process modifi...
- Characterization of ferromagnetic sludge-based act...
- High contribution of the particulate uptake pathwa...
- Estimation of decrease in cancer risk by biodegrad...
- Methyl acrylate modified apple pomace as promising...
- Editorial Board
- Identification of novel autoantigens via mass spec...
- Synaptic proteome changes in the hypothalamus of m...
- Earwax: A neglected body secretion or a step ahead...
- Broken Heart Syndrome – An intra operative complic...
- Our auditory results using the Vibrant Soundbridge...
- Addiction: an underestimated problem in psoriasis ...
- The clinical manifestations of vestibular migraine...
- Our auditory results using the Vibrant Soundbridge...
- The clinical manifestations of vestibular migraine...
- Hypofractionated radiotherapy in older patients wi...
- Hypofractionated radiotherapy in older patients wi...
- Vitamin D supplementation in pregnancy, prenatal 2...
- Three-dimensional cardiac microtissues composed of...
- Engineering intravaginal vaccines to overcome muco...
- G protein-coupled calcium-sensing receptor is a cr...
- Tolerability, usability and acceptability of disso...
- Surface engineering of semiconducting polymer nano...
- Incidence of hidradenitis suppurativa in the Unite...
- Calciphylaxis: Comparison of radiologic imaging an...
- Pediatric Stevens-Johnson syndrome and toxic epide...
- Histopathological changes in morphea and their cli...
- Proximal upper limb jerking: important clinical si...
- Graphene oxide functionalized long period grating ...
- Quantum-dots-based photoelectrochemical bioanalysi...
- Label-free identification of activated T lymphocyt...
- Nanosphere-based one-step strategy for efficient a...
- DNA-mediated inhibition of peroxidase-like activit...
- Multiplex detection of extensively drug resistant ...
- A highly sensitive electrochemical immunosensor fo...
-
▼
Μαρ 09
(457)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Πέμπτη 9 Μαρτίου 2017
PET/TC con 18F-FDG como predictor de la biología tumoral y del pronóstico en el cáncer epitelial ovárico
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
►
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
▼
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
-
▼
Μαρτίου
(11966)
-
▼
Μαρ 09
(457)
- Voice outcomes for early laryngeal cancer.
- Social and quality of life impact using a voice pr...
- Dysphagia management in tracheostomized patients: ...
- Voice and swallowing outcomes for adults undergoin...
- The use of practice guidelines in the management o...
- Self-reported postoperative recovery in children a...
- Foreign body aspiration in children: Focus on the ...
- Anti-angiogenic treatment for breast cancer?
- The role of drug-drug interactions in prostate can...
- Incidental Findings on Pediatric Abdominal Magneti...
- Dosimetric Analysis of Liver Toxicity Post Liver M...
- Outcomes and Toxicity following High-Dose Radiatio...
- Persistent nasal carriers of Acinetobacter baumann...
- A New Keystone Flap “Plus” Design: Case Series and...
- Failure to Diagnose an Incompetent Cervix,Prematur...
- Permanent prostate brachytherapy pubic arch evalua...
- Assessment of clinical and radiologic differences ...
- Use of hepatobiliary phase images in Gd-EOB-DTPA-e...
- Unusual ultrasound appearance of small bowel intus...
- Contrast-enhanced ultrasound and computed tomograp...
- Neocortical and hippocampal TREM2 protein levels d...
- Engineering intravaginal vaccines to overcome muco...
- Islet encapsulation with polyphenol coatings decre...
- Tolerability, usability and acceptability of disso...
- TANTIGEN: a comprehensive database of tumor T cell...
- Murine Th17 cells utilize IL-2 receptor gamma chai...
- Acoustic Context Alters Vowel Categorization in Pe...
- Verrucarin A and roridin E produced on spinach by ...
- Withdrawing ASV therapy in clinical practice: tria...
- Risk of developing obstructive sleep apnea among w...
- Natural course and potential prognostic factors fo...
- The Transient Receptor Potential Melastatin 7 Chan...
- Reactivating p53 and Inducing Tumor Apoptosis (RIT...
- Noninvasive Bioluminescence Imaging of AKT Kinase ...
- Emergency cricothyrotomy: temporary measure or def...
- Foreign body aspiration in children: Focus on the ...
- Close surgical margin after conservative parotidec...
- Our auditory results using the Vibrant Soundbridge...
- The clinical manifestations of vestibular migraine...
- Comparing performance of Fastrach ILMA vs flexible...
- Targeting BMI1+ Cancer Stem Cells Overcomes Chemor...
- PRC2 Facilitates the Regulatory Topology Required ...
- Mex3a Marks a Slowly Dividing Subpopulation of Lgr...
- New in vivo model to analyse the expression of ang...
- Stimuli-responsive shell cross-linked micelles fro...
- Novel endodontic sealers induce cell cytotoxicity ...
- Root canal morphology and variations in mandibular...
- Lipid parameters in obese and normal weight patien...
- Odontogenic differentiation potential of human den...
- Integrative Proteomics and Phosphoproteomics Profi...
- Concentration-dependent alterations in gene expres...
- Iron-based adsorbent prepared from Litchi peel bio...
- Amelioration of boron toxicity in sweet pepper as ...
- Effect of foliar application of plant growth regul...
- Withered on the stem: is bamboo a seasonally limit...
- Frequencies of erythrocyte nuclear abnormalities a...
- Using early life stages of marine animals to scree...
- Toxic effect of nonylphenol on the marine macroalg...
- Unique characteristics of algal dissolved organic ...
- Precipitation and air temperature control the vari...
- The death of the circulatory system diseases in Ch...
- Slow-release formulations of the herbicide piclora...
- Migration of nitrate, nitrite, and ammonia through...
- Investigations of temperature and pH variations on...
- Enhancing filterability of activated sludge from l...
- Enhanced heterogeneous photo-Fenton process modifi...
- Characterization of ferromagnetic sludge-based act...
- High contribution of the particulate uptake pathwa...
- Estimation of decrease in cancer risk by biodegrad...
- Methyl acrylate modified apple pomace as promising...
- Editorial Board
- Identification of novel autoantigens via mass spec...
- Synaptic proteome changes in the hypothalamus of m...
- Earwax: A neglected body secretion or a step ahead...
- Broken Heart Syndrome – An intra operative complic...
- Our auditory results using the Vibrant Soundbridge...
- Addiction: an underestimated problem in psoriasis ...
- The clinical manifestations of vestibular migraine...
- Our auditory results using the Vibrant Soundbridge...
- The clinical manifestations of vestibular migraine...
- Hypofractionated radiotherapy in older patients wi...
- Hypofractionated radiotherapy in older patients wi...
- Vitamin D supplementation in pregnancy, prenatal 2...
- Three-dimensional cardiac microtissues composed of...
- Engineering intravaginal vaccines to overcome muco...
- G protein-coupled calcium-sensing receptor is a cr...
- Tolerability, usability and acceptability of disso...
- Surface engineering of semiconducting polymer nano...
- Incidence of hidradenitis suppurativa in the Unite...
- Calciphylaxis: Comparison of radiologic imaging an...
- Pediatric Stevens-Johnson syndrome and toxic epide...
- Histopathological changes in morphea and their cli...
- Proximal upper limb jerking: important clinical si...
- Graphene oxide functionalized long period grating ...
- Quantum-dots-based photoelectrochemical bioanalysi...
- Label-free identification of activated T lymphocyt...
- Nanosphere-based one-step strategy for efficient a...
- DNA-mediated inhibition of peroxidase-like activit...
- Multiplex detection of extensively drug resistant ...
- A highly sensitive electrochemical immunosensor fo...
-
▼
Μαρ 09
(457)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου