Platelet rich plasma for treatment of nonscarring hair loss: systematic review of literature.

Platelet rich plasma for treatment of nonscarring hair loss: systematic review of literature.

J Dermatolog Treat. 2017 Mar 08;:1-23

Authors: Ayatollahi A, Hosseini H, Gholami J, Mirminachi B, Firooz F, Firooz A

Abstract
BACKGROUND: Although there are many studies showing the role of platelet rich plasma (PRP) in bone grafts, teeth osteosynthesis, and wound healing, there have been little peer reviewed studies about the safety and efficacy of PRP application in the treatment of hair loss.
MATERIALS AND METHODS: In this systematic review, we searched Ovid Medline, Scopus and Web of Knowledge till November 2015 for human studies evaluating the efficacy of PRP for the treatment of noncicatricial alopecia.
RESULTS: Among 704 papers retrieved in first search, 18 papers matched our inclusion criteria, 14 for androgenic alopecia and 4 for alopecia areata. They included 2 case reports, 8 case series, 6 controlled clinical trials, and only 2 randomized controlled trials.
CONCLUSION: Most of the available evidence has shown low quality and controversial results about the efficacy of PRP in treating non cicatricial alopecias, including androgenetic alopecia and alopecia areata. Further randomized controlled studies with more sample size and standard protocols regarding the number and interval of treatment sessions, number of platelets, method of activation, etc, are required to investigate the efficacy and safety of PRP in treating hair loss.

PMID: 28271918 [PubMed - as supplied by publisher]

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