Comparing the sensitivity of auramine-rhodamine fluorescence to polymerase chain reaction in the detection of Mycobacterium leprae in Fite-negative tissue sections

To the Editor: Twenty-three skin biopsy specimens from 18 patients with leprosy that were Fite-negative but positive by polymerase chain reaction studies were stained with auramine-rhodamine (AR) and examined under a fluorescent microscope. The clinical features and details of armadillo exposure have been described in a separate report. The current study focused on the utility of AR staining in these patients.

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