Optimal needle length for epinephrine prefilled syringe in children

Patients with a history of anaphylaxis have a strong indication for the use of epinephrine auto-injectors (EAIs).1 However, EAIs are available in only 59.1% of countries according to a recent report from the World Allergy Organization.2 Appropriate EAI needle length for delivering epinephrine into intramuscular tissues has been studied in adults3–5 and children.6–8 EAIs also require a pressure trigger for delivery of epinephrine, which compresses the subcutaneous tissues and thus shortens the skin-to-muscle depth (STMD).

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